Abnormal Lung Function in Adults With Congenital Heart Disease: Prevalence, Relation to Cardiac Anatomy, and Association With Survival

Arrhythmias in adult CHD patients represent the leading cause of morbidity and hospitalization, resulting in a major increase in ablation and device-related procedures in these patients. These procedures are often complex, not only because of underlying congenital anatomic variations but also because of the effects of prior surgical repair that can modify the arrhythmic substrate leading to an increased likelihood of multiple types of arrhythmias, even in the same patient. To optimize both success and safety with these procedures, the electrophysiologist must be thoroughly familiar with the underlying cardiac anatomy, prior cardiac surgical history, and known variants of both the pathology and surgical techniques. The purpose of this chapter is to outline the salient concepts and principles pertinent to arrhythmia and device management in patients with CHD.

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Inspiratory muscle dysfunction and restrictive lung function impairment in congenital heart disease: Association with immune inflammatory response and exercise intolerance

International Journal of Cardiology ◽

10.1016/j.ijcard.2020.06.055 ◽

2020 ◽

Vol 318 ◽

pp. 45-51

Author(s):

Jens Spiesshoefer ◽

Stefan Orwat ◽

Carolin Henke ◽

Hans-Joachim Kabitz ◽

Stratis Katsianos ◽

...

Keyword(s):

Congenital Heart Disease ◽

Heart Disease ◽

Lung Function ◽

Congenital Heart ◽

Disease Association ◽

Exercise Intolerance ◽

Muscle Dysfunction ◽

Function Impairment ◽

Lung Function Impairment ◽

Restrictive Lung Function

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Lung function test in children with left-to-right shunt congenital heart disease

Paediatrica Indonesiana ◽

10.14238/pi58.4.2018.165-9 ◽

2018 ◽

Vol 58 (4) ◽

pp. 165-9

Author(s):

Carolina Kurniawan ◽

Indah Kartika Murni ◽

Sasmito Nugroho ◽

Noormanto Noormanto ◽

Roni Naning

Keyword(s):

Congenital Heart Disease ◽

Pulmonary Hypertension ◽

Heart Disease ◽

Lung Function ◽

Congenital Heart ◽

Vital Capacity ◽

Septal Defect ◽

Forced Expiratory Volume ◽

Significant Difference ◽

Restrictive Lung Function

Background Increased pulmonary blood flow may lead to abnormal lung function in children with left-to-right (L to R) shunt congenital heart disease. This condition has been linked to considerable mortality and morbidity, including reduced lung function. Objective To assess for lung function abnormality in children with L to R shunt congenital heart disease. Methods We conducted a cross-sectional study involving children aged 5-18 years and diagnosed with L to R shunt congenital heart disease at Dr. Sardjito Hospital from March to May 2017. Subjects underwent spirometry tests to measure forced expiratory volume-1 (FEV-1), forced vital capacity (FVC), and forced expiratory volume-1 (FEV-1)/forced vital capacity (FVC). Results Of 61 eligible subjects, 30 (49.2%) children had atrial septal defect (ASD), 25 (41%) children had ventricular septal defect (VSD), and 6 (9.8%) children had patent ductus arteriosus (PDA). Spirometry revealed lung function abnormalities in 37 (60.7%) children. Restrictive lung function was documented in 21/37 children, obstructive lung function in 11/37 children, and mixed pattern of lung function abnormality in 5/37 children. Pulmonary hypertension was found in 21 children. There was no significant difference in lung function among children with and without pulmonary hypertension (P=0.072). Conclusion Abnormal lung function is prevalent in 60.7% of children with L to R shunt congenital heart disease, of which restrictive lung function is the most common. There was no significant difference in lung function among children with and without pulmonary hypertension.

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