Effects of Continuous Positive Airway Pressure on Exhaled Transforming Growth Factor ß and Vascular Endothelial Growth Factor in Patients with Obstructive Sleep Apnea

2019 ◽  
Author(s):  
C.-C. Lin ◽  
M.-W. Lin ◽  
C.-H. Chiu
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Obstructive Sleep Apnea ◽  
Growth Factor ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Transforming Growth Factor ◽  
Positive Airway Pressure ◽  
Vascular Endothelial ◽  
Obstructive Sleep ◽  
Endothelial Growth Factor

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

Blood ◽  
2001 ◽  
Vol 98 (4) ◽  
pp. 1255-1257 ◽  
Author(s):  
Shigehiko Imagawa ◽  
Yuji Yamaguchi ◽  
Masato Higuchi ◽  
Tomohiro Neichi ◽  
Yuichi Hasegawa ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Obstructive Sleep ◽  
A Minor ◽  
Endothelial Growth Factor ◽  
Hypopnea Syndrome ◽  
Serum Erythropoietin

To better understand how humans adapt to hypoxia, the levels of hemoglobin (Hb), serum erythropoietin (Epo), and vascular endothelial growth factor (VEGF) were measured in 106 patients with severe obstructive sleep apnea-hypopnea syndrome. The results indicated that temporal hypoxic stimulation increases Hb. Furthermore, a minor increase in Epo and a substantial increase in VEGF were found. The induction in patients with severe sleep apnea was greater than that reported in other types of hypoxia.

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