Transient Receptor Potential Vanilloid 4 (TRPV4) Regulates the Host Defense Response to Bacterial Pneumonia Through a MAPK Molecular Switch

Receptor Potential ◽

Molecular Switch ◽

Host Defense Response ◽

Transient Receptor Potential Vanilloid 4 (TRPV4) Protects the Lung from Bacterial Pneumonia via MAPK Molecular Switching

10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7704 ◽

2020 ◽

Author(s):

R.G. Scheraga ◽

S. Abraham ◽

L. Grove ◽

B.D. Southern ◽

J. Crish ◽

...

Keyword(s):

Bacterial Pneumonia ◽

Receptor Potential ◽

Molecular Switching ◽

Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.8b00734 ◽

2018 ◽

Vol 61 (18) ◽

pp. 8255-8281 ◽

Cited By ~ 4

Author(s):

Aniello Schiano Moriello ◽

Silvia López Chinarro ◽

Olalla Novo Fernández ◽

Jordi Eras ◽

Pietro Amodeo ◽

...

Keyword(s):

Receptor Potential ◽

Molecular Switch ◽

Hydrophobic Chain ◽

Transient Receptor ◽

Endogenous Lipids

Faculty Opinions recommendation of Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047186.497222 ◽

2006 ◽

Author(s):

Alastair Ferguson

Keyword(s):

Receptor Potential ◽

Lamina Terminalis ◽

Organum Vasculosum Lamina Terminalis ◽

Organum Vasculosum ◽

Faculty Opinions recommendation of Transient receptor potential vanilloid 1 is required for intrinsic osmoreception in organum vasculosum lamina terminalis neurons and for normal thirst responses to systemic hyperosmolality.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047186.497108 ◽

2006 ◽

Author(s):

Bernd Nilius

Keyword(s):

Receptor Potential ◽

Lamina Terminalis ◽

Organum Vasculosum Lamina Terminalis ◽

Organum Vasculosum ◽

Faculty Opinions recommendation of Somatostatin modulates the transient receptor potential vanilloid 1 (TRPV1) ion channel.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1052995.504951 ◽

2006 ◽

Author(s):

Marcos Milla

Keyword(s):

Ion Channel ◽

Receptor Potential ◽

Faculty Opinions recommendation of A specific subset of transient receptor potential vanilloid-type channel subunits in Caenorhabditis elegans endocrine cells function as mixed heteromers to promote neurotransmitter release.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1063770.516694 ◽

2007 ◽

Author(s):

Oliver Hobert

Keyword(s):

Caenorhabditis Elegans ◽

Neurotransmitter Release ◽

Endocrine Cells ◽

Receptor Potential ◽

Specific Subset ◽

Faculty Opinions recommendation of Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1100237.558108 ◽

2008 ◽

Author(s):

Rodolfo Testa

Keyword(s):

Receptor Potential ◽

Faculty Opinions recommendation of Design and synthesis of peripherally restricted transient receptor potential vanilloid 1 (TRPV1) antagonists.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108621.564704 ◽

2008 ◽

Author(s):

Rodolfo Testa

Keyword(s):

Receptor Potential ◽

Design And Synthesis ◽

Faculty Opinions recommendation of The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7001.464490 ◽

2006 ◽

Author(s):

Gyongyi Horvath

Keyword(s):

Ion Channel ◽

Inflammatory Mediators ◽

Receptor Potential ◽

Mouse Colon ◽

Afferent Fibers ◽

Faculty Opinions recommendation of Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718012518.793477186 ◽

2013 ◽

Author(s):

Arpad Szallasi

Keyword(s):

Receptor Potential ◽

Inflammatory Hyperalgesia ◽