scholarly journals Profile of Interstitial Lung Disease at the University of Nigeria Teaching Hospital Enugu, Nigeria

2020 ◽  
Author(s):  
N.I. Nwosu ◽  
V. Uduma ◽  
P. Nlewedim ◽  
K.N. Ukwaja ◽  
C. Onyedum ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Teaching Hospital ◽  
Nigeria Teaching Hospital ◽  
The University

scholarly journals Experience and perception of virtual clinical conferencing during COVID-19 pandemic by doctors at the university of Nigeria Teaching Hospital Enugu, Nigeria

2021 ◽  
Vol 30 (5) ◽  
pp. 567
Author(s):  
JohnpaulEjikeme Nnagbo ◽  
CyrilChukwudi Dim ◽  
EkeomaO Nwosu ◽  
EmmanuelOnyebuchi Ugwu ◽  
ObinnaDonatus Onodugo
Keyword(s):  
Teaching Hospital ◽  
Nigeria Teaching Hospital ◽  
The University

An audit of the first three years of mammography and sono-mammography at the University of Nigeria Teaching Hospital, Enugu, Nigeria.

2013 ◽  
Vol 17 (2) ◽  
pp. 39
Author(s):  
P Okere ◽  
A Aderibigbe ◽  
N Iloanusi ◽  
DB Olusina ◽  
D Itanyi ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Nigeria Teaching Hospital ◽  
The University

scholarly journals Peripheral blood leucocyte telomere length is associated with progression of interstitial lung disease in systemic sclerosis

Thorax ◽  
2021 ◽  
pp. thoraxjnl-2020-215918
Author(s):  
Shuo Liu ◽  
Melody P Chung ◽  
Brett Ley ◽  
Sarah French ◽  
Brett M Elicker ◽  
...  
Keyword(s):  
Systemic Sclerosis ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Telomere Length ◽  
San Francisco ◽  
Longitudinal Analysis ◽  
Peripheral Blood ◽  
Peripheral Blood Leucocyte ◽  
Increased Risk ◽  
The University

BackgroundPeripheral blood leucocyte telomere length (PBL-TL) is associated with outcomes in patients with idiopathic pulmonary fibrosis. Whether PBL-TL is associated with progression of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is unknown.MethodsA retrospective observational cohort study was performed using prospectively collected data from 213 patients with SSc followed at the University of California San Francisco (UCSF) Scleroderma Center. PBL-TL was measured by quantitative PCR of DNA isolated from peripheral blood. Associations between PBL-TL and pulmonary function test trends in patients with SSc-ILD were assessed by longitudinal analysis using Generalised Linear Mixed Models. Findings were validated in a cohort of 61 patients with SSc-ILD enrolled in the Stanford University Scleroderma Center database.ResultsPatients with UCSF SSc with ILD were found to have shorter PBL-TL compared with those without ILD (6554±671 base pairs (bp) vs 6782±698 bp, p=0.01). Shorter PBL-TL was associated with the presence of ILD (adjusted OR 2.1 per 1000 bp TL decrease, 95% CI [1.25 to 3.70], p=0.006). PBL-TL was shorter in patients with SSc-ILD lacking SSc-specific autoantibodies compared with seropositive subjects (6237±647 bp vs 6651±653 bp, p=0.004). Shorter PBL-TL was associated with increased risk for lung function deterioration with an average of 67 mL greater loss in per year for every 1000 bp decrease in PBL-TL in the combined SSc-ILD cohorts (longitudinal analysis, adjusted model: 95% CI −104 mL to −33 mL, p<0.001).ConclusionsThese findings suggest that telomere dysfunction may be associated with SSc-ILD progression and that PBL-TL measurement may be useful for stratifying risk for SSc-ILD progression.

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