scholarly journals Introduction to Radioactive Materials

2014 ◽  
Vol 3 (3) ◽  
pp. 59 ◽  
Author(s):  
Askari Mohammad Bagher
Keyword(s):  
Radioactive Materials

Discussion on “The Sir Alfred Herbert paper, 1953. The industrial applications of radioactive materials”

1953 ◽  
Vol 32 (10) ◽  
pp. 450
Author(s):  
F.E. Simon ◽  
John Cockcroft ◽  
Henry Seligman ◽  
Burton Foringer ◽  
A.O'B Brandon ◽  
...  
Keyword(s):  
Industrial Applications ◽  
Radioactive Materials

APPLICATION OF ESCA AND AES TO HIGHLY RADIOACTIVE MATERIALS

1984 ◽  
Vol 45 (C2) ◽  
pp. C2-841-C2-844 ◽  
Author(s):  
J. R. Naegele
Keyword(s):  
Radioactive Materials

STUDIES ON THYROIDAL COLLOID PINOCYTOSIS USING A DOUBLE ISOTOPE TECHNIQUE

1972 ◽  
Vol 70 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Mario A. Pisarev ◽  
Noe Altschuler ◽  
Leslie J. DeGroot
Keyword(s):  
Acid Phosphatase ◽  
Thyroid Hormone ◽  
Trichloroacetic Acid ◽  
Specific Activity ◽  
Acid Precipitation ◽  
Solvent System ◽  
Blood Stream ◽  
Radioactive Materials ◽  
Isotope Technique ◽  
Double Isotope

ABSTRACT The process of secretion of the thyroid hormone involves several steps: pinocytosis of thyroglobulin, fusion of the colloid droplets with the lysosomes, digestion of thyroglobulin by a cathepsin, dehalogenation of tyrosines and release of thyronines into the blood stream. The present paper describes a double isotope technique for studying the first two steps. Thyrotrophin (TSH) administration to rats increased the radioactivity present in all fractions, specially in the 15 000 × g pellet. When the subcellular distribution of acid phosphatase was determined, the highest specific activity was found in this fraction, thus indicating the presence of lysosomes. The content of radioactive materials in the 15 000 × g pellet was analyzed by trichloroacetic acid precipitation and by ascending paper chromatography using n-butanol:ethanol:ammonium hydroxide (5:1:2;v/v) as solvent system. The results obtained showed that 90% of the radioactivity was protein bound and strongly suggest that this material is thyroglobulin.

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