Study on the Immediate Effect of Passive Motion in Patients with Hemiplegia Based on Brain Functional Magnetic Resonance Imaging

2020 ◽  
Vol 10 (7) ◽  
pp. 1693-1703
Author(s):  
Jian Tao ◽  
Weili Hu

In order to explore the immediate effect of passive motion in patients with hemiplegia based on brain functional magnetic resonance imaging (fMRI), a total of 100 patients, who were diagnosed as stroke hemiplegia and underwent fMRI examination at a hospital designated by this study from December 2016 to December 2018, were chose as study subjects and were divided into observation group and control group according to the random number table method with 50 cases of patients in each group. The fMRI examinations were performed in the 2 groups of patients within 1 week after treatment; 10 voxels were taken as effective activating voxels to obtain statistical parameter maps for region of interest analysis; and bilateral cerebral hemispheres, sensorimotor cortex and supplementary motor area were selected as the region of interest to calculate the number of activated voxels respectively; the clinical neurological deficit scale, simplified motor function scale, and functional independence assessment table are used for the evaluation of the 2 groups of patients at the beginning and after 8 weeks of treatment. The results show that all patients’ fMRI examinations are characterized by motor function area cerebral infarction or corresponding corticospinal tract cerebral infarction; the healthy side finger movement function area is basically normal in the brain function imaging examination; the cortical signal regions are concentrated in the vicinity of the central frontal first motion zone and the central posterior proprioception zone with strong repeatability when the active, passive and resistance-inducing active movements are respectively performed on the healthy side; and the contralateral sensorimotor cortex and bilateral auxiliary exercise areas were activated. The hemiplegia patients had increased activation of the hemisphere during hand movement, and the fMRI results were basically the same as those of the normal subjects. Therefore, the fMRI examination can provide imaging data for cortical functional zone localization of active and passive movements of the fingers, and provide assistance for clinical rehabilitation and prognosis assessment. The results of this study provide a reference for further researches on the immediate effects of passive motion in patients with hemiplegia based on brain functional magnetic resonance imaging.

2016 ◽  
Vol 125 (5) ◽  
pp. 861-872 ◽  
Author(s):  
Andreas Ranft ◽  
Daniel Golkowski ◽  
Tobias Kiel ◽  
Valentin Riedl ◽  
Philipp Kohl ◽  
...  

Abstract Background The neural correlates of anesthetic-induced unconsciousness have yet to be fully elucidated. Sedative and anesthetic states induced by propofol have been studied extensively, consistently revealing a decrease of frontoparietal and thalamocortical connectivity. There is, however, less understanding of the effects of halogenated ethers on functional brain networks. Methods The authors recorded simultaneous resting-state functional magnetic resonance imaging and electroencephalography in 16 artificially ventilated volunteers during sevoflurane anesthesia at burst suppression and 3 and 2 vol% steady-state concentrations for 700 s each to assess functional connectivity changes compared to wakefulness. Electroencephalographic data were analyzed using symbolic transfer entropy (surrogate of information transfer) and permutation entropy (surrogate of cortical information processing). Functional magnetic resonance imaging data were analyzed by an independent component analysis and a region-of-interest–based analysis. Results Electroencephalographic analysis showed a significant reduction of anterior-to-posterior symbolic transfer entropy and global permutation entropy. At 2 vol% sevoflurane concentrations, frontal and thalamic networks identified by independent component analysis showed significantly reduced within-network connectivity. Primary sensory networks did not show a significant change. At burst suppression, all cortical networks showed significantly reduced functional connectivity. Region-of-interest–based thalamic connectivity at 2 vol% was significantly reduced to frontoparietal and posterior cingulate cortices but not to sensory areas. Conclusions Sevoflurane decreased frontal and thalamocortical connectivity. The changes in blood oxygenation level dependent connectivity were consistent with reduced anterior-to-posterior directed connectivity and reduced cortical information processing. These data advance the understanding of sevoflurane-induced unconsciousness and contribute to a neural basis of electroencephalographic measures that hold promise for intraoperative anesthesia monitoring.


2021 ◽  
Vol 11 (6) ◽  
pp. 1761-1770
Author(s):  
Ding Zhang ◽  
Gang Liu ◽  
Liemi Huang ◽  
Lun Zhang ◽  
Xinghua Gui ◽  
...  

Through functional magnetic resonance imaging (fMRI) technology, it is planned to use complex brain network technology to track brain functional imaging tracking treatment of stroke hemiplegia with scalp acupuncture. Functional magnetic resonance imaging (fMRI) can continuously monitor the rehabilitation process of motor nerve function in patients with stroke and upper limb hemiplegia, and explore the mechanism of brain plasticity changes at different levels of neural function cortex, motor function neural circuit, and behavior level. First, the fMRI test uses a block design, and the subjects complete the movement of the thumb and index finger. After completing the dysfunction assessment, fMRI data collection was performed on the patient before the CIMT treatment using a magnetic resonance apparatus, and a second fMRI data collection was performed 2 weeks after the CIMT treatment; only one fMRI data collection was performed on the volunteers. The functional magnetic resonance data was processed using the AFNI software package, and the functional scores of subjects were calculated using SPSS software. Second, studying the remodeling of residual brain tissue and functional compensation pathways can help to further clarify the recovery mechanism of motor function after stroke hemiplegia. Finally, compulsory exercise therapy can effectively improve upper limb motor dysfunction in stroke patients. The forced use of upper extremities during treatment induces the reorganization and compensation of cerebral cortical functional areas. This change in brain functional areas is consistent with the increase of upper extremity movement and improvement of motor function, fMRI can provide neuronal reorganization after exercise therapy evidence with compensation.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Adnan A. S. Alahmadi

Abstract Objectives Traditionally, the superior parietal lobule (SPL) is usually investigated as one region of interest, particularly in functional magnetic resonance imaging (fMRI) studies. However, cytoarchitectonic analysis has shown that the SPL has a complex, heterogeneous topology that comprises more than seven sub-regions. Since previous studies have shown how the SPL is significantly involved in different neurological functions—such as visuomotor, cognitive, sensory, higher order, working memory and attention—this study aims to investigate whether these cytoarchitecturally different sub-regions have different functional connectivity to different functional brain networks. Methods This study examined 198 healthy subjects using resting-state fMRI and investigated the functional connectivity of seven sub-regions of the SPL to eight regional functional networks. Results The findings showed that most of the seven sub-regions were functionally connected to these targeted networks and that there are differences between these sub-regions and their functional connectivity patterns. The most consistent functional connectivity was observed with the visual and attention networks. There were also clear functional differences between Brodmann area (BA) 5 and BA7. BA5, with its three sub-regions, had strong functional connectivity to both the sensorimotor and salience networks. Conclusion These findings have enhanced our understanding of the functional organisations of the complexity of the SPL and its varied topology and also provide clear evidence of the functional patterns and involvements of the SPL in major brain functions.


Sign in / Sign up

Export Citation Format

Share Document