Synthesis and fluorescence of novel complexes of tricyano-dihydrofuran and ofloxacin

2021 ◽  
Vol 11 (11) ◽  
pp. 1781-1785
Author(s):  
Huizhu Zhang ◽  
Liang Ming ◽  
Tao Zhang ◽  
Baohui Guo ◽  
Yuguang Lv
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Infrared Spectroscopy ◽  
Charge Transfer ◽  
Fluorescent Probe ◽  
Charge Transfer Complex ◽  
Fluorescence Spectrophotometry ◽  
Fluorescent Nanoprobe ◽  
First Time

Quinolones are widely used, but there are few reports on the application of fluorescent probe analysis. In this paper, we synthesized a tricyano-dihydrofuran (DCDHF-2-V) electron acceptor, and a (DCDHF-2-V)-quinolone fluorescent nanoprobe was designed. Its structure was characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR) and ultraviolet (UV). A novel tricyano-dihydrofuran-ofloxacin fluorescent nanoprobe was established for the first time by fluorescence spectrophotometry. A novel fluorescent nanoprobe was obtained and used in the determination of ofloxacin in vitro. The results showed that tricyano-dihydrofuran can form stable charge transfer complex with ofloxacin, and it can be used for the determination of ofloxacin in drugs as a fluorescent probe. While important experimental steps are for the first time achieved in this study for future Quinolone fluorescent nanoprobe implementations, this method is simple and sensitive.

Carbon dots derived from Fusobacterium nucleatum for intracellular determination of Fe3+ and bioimaging both in vitro and in vivo

2021 ◽  
Author(s):  
Lijuan Liu ◽  
Shengting Zhang ◽  
Xiaodan Zheng ◽  
Hongmei Li ◽  
Qi Chen ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fusobacterium Nucleatum ◽  
Living Cells ◽  
First Time ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Fusobacterium nucleatum has been employed for the first time to synthesize fluorescent carbon dots which could be applied for the determination of Fe3+ ions in living cells and bioimaging in vitro and in vivo with excellent biocompatibility.

scholarly journals DETERMINATION OF TRIMETHOPRIM BY CHARGE-TRANSFER COMPLEX FORMATION

1994 ◽  
Vol 3 (2) ◽  
pp. 132-141
Author(s):  
Mohamed El Balkiny ◽  
Gamal Ragab ◽  
Magda Ayad
Keyword(s):  
Charge Transfer ◽  
Complex Formation ◽  
Charge Transfer Complex

Feasibility of near Infrared Spectroscopy Determination of Haemoglobin-Related Blood Levels of Cattle: An in vitro Study

NIR news ◽  
2012 ◽  
Vol 23 (6) ◽  
pp. 13-14 ◽  
Author(s):  
Akifumi Ikehata ◽  
Kunio Sashida ◽  
Shanji Park ◽  
Tsutomu Okura ◽  
Yutaka Terada
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
In Vitro Study ◽  
Vitro Study ◽  
Blood Levels

scholarly journals Sensitive Spectrophotometric Determinations of Paracetamol and Protriptyline HCl Using 3-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Kumble Divya ◽  
Badiadka Narayana ◽  
Majal Sapnakumari
Keyword(s):  
Charge Transfer ◽  
Spectrophotometric Method ◽  
Charge Transfer Complex ◽  
Limit Of Detection ◽  
Pharmaceutical Formulations ◽  
Molar Absorptivity ◽  
Pharmaceutical Samples ◽  
Chromogenic Reagent ◽  
Detection And Quantification

A new spectrophotometric method is developed for the determination of Paracetamol (PCT) and protriptyline HCl (PTP) in pure forms and in pharmaceutical formulations. The experiment involves the use of 3-chloro-7-hydroxy-4-methyl-2H-chromen-2-one as a novel chromogenic reagent for the determination of PCT and PTP. The method is based on the formation of charge transfer complex between the drugs and chromogenic reagent. Beer's law is obeyed in the concentration ranges 10.00–60.00 µg mL−1 for PCT at 545 nm and 40.00–160.00 µg mL−1 for PTP at 468 nm. The molar absorptivity, Sandell, sensitivity, and limit of detection and quantification are also calculated. The method has been successfully applied for the determination of both PCT and PTP in pharmaceutical samples with acceptable results.

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