scholarly journals Biometric Factors Associated With Acute Primary Angle Closure: Comparison of the Affected and Fellow Eye

2016 ◽  
Vol 57 (13) ◽  
pp. 5320 ◽  
Author(s):  
Eray Atalay ◽  
Monisha E. Nongpiur ◽  
Mani Baskaran ◽  
Sourabh Sharma ◽  
Shamira A. Perera ◽  
...  
Keyword(s):  
Angle Closure ◽  
Fellow Eye ◽  
Acute Primary Angle Closure ◽  
Factors Associated ◽  
Primary Angle Closure

Blindness short after treatment of acute primary angle closure in China

2020 ◽  
pp. bjophthalmol-2020-316259
Author(s):  
Shuning Li ◽  
Guangxian Tang ◽  
Su Jie Fan ◽  
Gang Zhai ◽  
Jianhua Lv ◽  
...  
Keyword(s):  
Risk Factors ◽  
Time Window ◽  
Case Series ◽  
Critical Time ◽  
Education Level ◽  
Angle Closure ◽  
Retrospective Case ◽  
Acute Primary Angle Closure ◽  
Factors Associated ◽  
Primary Angle Closure

AimsTo study the risk factors associated with blindness after treatment of acute primary angle closure (APAC), and to identify the critical time window to decrease rate of blindness.MethodsIn this multicentre retrospective case series, 1030 consecutive subjects (1164 eyes) with APAC in China were recruited. The rates of blindness were analysed up to 3 months after treatment of APAC. A logistic regression was used to identify the risk factors associated with blindness, including age, gender, distance to hospital, rural or urban settings, treatment method, education level, time from symptom to treatment (TST, hours) and presenting intraocular pressure (IOP). The critical time window associated with a blindness rate of ≤1% was calculated based on a cubic function by fitting TST to the rate of blindness at each time point.ResultsThe rate of blindness after APAC was 12.54% after treatment. In multivariate regression, education level, TST and presenting IOP were risk factors for blindness (p=0.022, 0.004 and 0.001, respectively). The critical time window associated with a blindness rate of ≤1% was 4.6 hours.Conclusions and relevanceEducation level, TST and presenting IOP were risk factors for blindness after APAC. Timely medical treatment is key in reducing blindness after APAC.

scholarly journals Evaluation of Anterior Segment Parameters of First-Time Acute Primary Angle Closure Eye and the Fellow Eye: A Cross-Sectional Study

2018 ◽  
Author(s):  
Di Chen ◽  
Shunhua Zhang ◽  
Ailing Bian ◽  
Yang Zhang ◽  
Jialiang Zhao
Keyword(s):  
Logistic Regression ◽  
Anterior Chamber ◽  
Conditional Logistic Regression ◽  
Anterior Segment ◽  
Angle Closure ◽  
Fellow Eye ◽  
Acute Primary Angle Closure ◽  
Primary Angle Closure ◽  
Anterior Segment Parameters ◽  
First Time

Abstract Background: To evaluate the anterior segment parameters of first-time acute primary angle closure(APAC) eye and the fellow eye (primary angle closure suspect, PACS) with anterior segment optical coherence tomography (AS-OCT) and analyze the possible factors associated with the attack of APAC. Methods: Thirty patients with first-time unilateral APAC (APAC 30eyes, PACS 30eyes) were collected from August 2013 to August 2014 in the ophthalmology department of Peking Union Medical College Hospital. Central cornea thickness (CCT), pupil diameter (PD), anterior chamber depth (ACD), lens vault (LV), anterior chamber width (ACW), angle open distance at 500μmand 750μm from the sclera spur (AOD500, AOD750), trabecular iris area at 500μmand 750μm from the sclera spur(TISA500, TISA750), sclera spur angle (SSA) of both eyes were measured by AS-OCT. Paired t-test was applied to find the differences and conditional logistic regression analysis was performed to find the associatedfactors with the prediction of APAC. Results: Compared with the fellow PACS eyes, first-time APAC eyes showed significantlarger CCT (522.7±31.3vs557.3±42.7mm,P=0.000), PD (2.90±1.19vs3.78±1.29mm, P=0.000) and LV (1.08±0.36vs1.24±0.42mm, P=0.006),smaller ACD (1.81±0.45vs1.64±0.44mm,P=0.001), AOD500 (0.097±0.065vs0.059±0.039,P=0.004), AOD750 (0.157±0.10vs0.120±0.068mm,P=0.017), TISA500 (0.036±0.021vs0.020±0.016mm2, P=0.001), TISA750 (0.065and 0.041mm2, P=0.018) and SSA (11.13±6.92and 6.68±4.43°, P=0.001). The results of conditional logistic regression analysisshowed greater LV(OR=40.259[1.021,1779.193],P=0.014) hadthe strongest correlation with the attack of APAC. Conclusions: Greater LV is the most significant factor associated withfirst-time APACcompared with the fellow PACS eye and may play a critical role in the progression of PACS to APAC.

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