scholarly journals Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic–induced necroptosis

JCI Insight ◽  
2020 ◽  
Vol 5 (23) ◽  
Author(s):  
Burak Uzunparmak ◽  
Meng Gao ◽  
Antje Lindemann ◽  
Kelly Erikson ◽  
Li Wang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Caspase 8 ◽  
Smac Mimetic

scholarly journals LCL161, a SMAC-mimetic, Preferentially Radiosensitizes Human Papillomavirus–negative Head and Neck Squamous Cell Carcinoma

2019 ◽  
Vol 18 (6) ◽  
pp. 1025-1035 ◽  
Author(s):  
Linlin Yang ◽  
Bhavna Kumar ◽  
Changxian Shen ◽  
Songzhu Zhao ◽  
Dukagjin Blakaj ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Smac Mimetic

Abstract 2055: The SMAC-mimetic Debio 1143 efficiently enhanced chemo and radiotherapy in head and neck squamous cell carcinoma models.

2013 ◽  
Author(s):  
David Viertl ◽  
Florence Perillo-Adamer ◽  
Stefania Rigotti ◽  
Jean-Luc Muralti ◽  
Hélène Maby-El Hajjami ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Smac Mimetic

Abstract 04: Caspase-8 is a novel candidate driver gene in head and neck squamous cell carcinoma

2017 ◽  
Author(s):  
Burak Uzunparmak ◽  
Antje Lindemann ◽  
Mitchell J. Frederick ◽  
Jeffrey N. Myers ◽  
Curtis R. Pickering
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Driver Gene ◽  
Caspase 8

The radiosensitizing activity of the SMAC-mimetic, Debio 1143, is TNFα-mediated in head and neck squamous cell carcinoma

2015 ◽  
Vol 116 (3) ◽  
pp. 495-503 ◽  
Author(s):  
Oscar Matzinger ◽  
David Viertl ◽  
Pelagia Tsoutsou ◽  
Linda Kadi ◽  
Stefania Rigotti ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Neck Squamous Cell Carcinoma ◽  
Smac Mimetic
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