Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E.

Journal of Clinical Investigation ◽

10.1172/jci1124 ◽

1998 ◽

Vol 102 (2) ◽

pp. 386-394 ◽

Author(s):

J Osuga ◽

M Yonemoto ◽

N Yamada ◽

H Shimano ◽

H Yagyu ◽

...

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Cholesterol Lowering ◽

Density Lipoprotein Receptor

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Transbilayer Distribution of Cholesterol Is Modified in Brain Synaptic Plasma Membranes of Knockout Mice Deficient in the Low-Density Lipoprotein Receptor, Apolipoprotein E, or Both Proteins

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1997.69041661.x ◽

1997 ◽

Vol 69 (4) ◽

pp. 1661-1667 ◽

Author(s):

Urule Igbavboa ◽

Nicolai A. Avdulov ◽

Svetlana V. Chochina ◽

W. Gibson Wood

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Plasma Membranes ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Synaptic Plasma Membranes ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Ticlopidine attenuates progression of atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

European Journal of Pharmacology ◽

10.1016/j.ejphar.2006.11.028 ◽

2007 ◽

Vol 556 (1-3) ◽

pp. 129-135 ◽

Author(s):

Jacek Jawien ◽

Gabor Csanyi ◽

Mariusz Gajda ◽

Lukasz Mateuszuk ◽

Magdalena Lomnicka ◽

...

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Double Knockout ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor ◽

Progression Of Atherosclerosis

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The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.91.10.4431 ◽

1994 ◽

Vol 91 (10) ◽

pp. 4431-4435 ◽

Author(s):

S. Ishibashi ◽

J. Herz ◽

N. Maeda ◽

J. L. Goldstein ◽

M. S. Brown

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Receptor Model ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Total body proteoglycan 4 (Prg4) deficiency increases atherosclerosis susceptibility in apolipoprotein E knockout and low-density lipoprotein receptor knockout mice

Atherosclerosis ◽

10.1016/j.atherosclerosis.2018.06.883 ◽

2018 ◽

Vol 278 ◽

pp. 315-316 ◽

Author(s):

Joya E. Nahon ◽

Menno Hoekstra ◽

Miranda Van Eck

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Proteoglycan 4 ◽

Density Lipoprotein Receptor ◽

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Lecithin:Cholesterol Acyltransferase Deficiency Increases Atherosclerosis in the Low Density Lipoprotein Receptor and Apolipoprotein E Knockout Mice

Journal of Biological Chemistry ◽

10.1074/jbc.m109883200 ◽

2001 ◽

Vol 277 (5) ◽

pp. 3511-3519 ◽

Author(s):

James W. Furbee ◽

Janet K. Sawyer ◽

John S. Parks

Keyword(s):

Apolipoprotein E ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Lecithin:Cholesterol Acyltransferase ◽

Low Density Lipoprotein Receptor ◽

Apolipoprotein E Knockout Mice ◽

Density Lipoprotein Receptor

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Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

British Journal of Pharmacology ◽

10.1038/sj.bjp.0704160 ◽

2001 ◽

Vol 133 (7) ◽

pp. 1005-1012 ◽

Author(s):

Tsuyoshi Chiwata ◽

Katsumi Aragane ◽

Koji Fujinami ◽

Kazuhiro Kojima ◽

Shun Ishibashi ◽

...

Keyword(s):

Apolipoprotein E ◽

Direct Effect ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Double Knockout ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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A nonexchangeable apolipoprotein E peptide that mediates binding to the low density lipoprotein receptor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)32027-6 ◽

1994 ◽

Vol 269 (32) ◽

pp. 20539-20547 ◽

Author(s):

M.P. Mims ◽

A.T. Darnule ◽

R.W. Tovar ◽

H.J. Pownall ◽

D.A. Sparrow ◽

...

Keyword(s):

Apolipoprotein E ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus

Neurobiology of Disease ◽

10.1016/j.nbd.2004.01.015 ◽

2004 ◽

Vol 16 (1) ◽

pp. 212-219 ◽

Author(s):

Monique Mulder ◽

Paula J Jansen ◽

Ben J.A Janssen ◽

Wilma D.J van de Berg ◽

Hans van der Boom ◽

...

Keyword(s):

Spatial Memory ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Synaptic Density ◽

Density Lipoprotein Receptor

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Low-Density Lipoprotein Receptor Knockout Mice Exhibit Exaggerated Microvascular Responses to Inflammatory Stimuli

Circulation Research ◽

10.1161/01.res.81.2.274 ◽

1997 ◽

Vol 81 (2) ◽

pp. 274-281 ◽

Author(s):

Dwight D. Henninger ◽

Mary E. Gerritsen ◽

D. Neil Granger

Keyword(s):

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Inflammatory Stimuli ◽

Density Lipoprotein Receptor

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Non-redundant roles for LXRα and LXRβ in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice

The Journal of Lipid Research ◽

10.1194/jlr.m900096-jlr200 ◽

2009 ◽

Vol 51 (5) ◽

pp. 900-906 ◽

Author(s):

Eric D. Bischoff ◽

Chris L. Daige ◽

Mary Petrowski ◽

Harry Dedman ◽

Jennifer Pattison ◽

...

Keyword(s):

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

Download Full-text