Benefits of Low-Intensity Pain-Free Treadmill Exercise on Functional Capacity of Individuals Presenting with Intermittent Claudication Due to Peripheral Arterial Disease

Angiology ◽  
2008 ◽  
Vol 60 (4) ◽  
pp. 477-486 ◽  
Author(s):  
Sharon Barak ◽  
Christine Boyd Stopka ◽  
Coleen Archer Martinez ◽  
Eli Carmeli
Keyword(s):  
Energy Expenditure ◽  
Peripheral Arterial Disease ◽  
Intermittent Claudication ◽  
Functional Capacity ◽  
Treadmill Exercise ◽  
Arterial Disease ◽  
Walking Distance ◽  
Metabolic Equivalent ◽  
Low Intensity ◽  
Peripheral Arterial

Patients with intermittent claudication due to peripheral arterial disease (PAD) experience muscle aching during walking secondary to ischemia. The purpose of this study was to examine the effects of low-intensity pain-free exercise (LIPFE) on functional capacity of individuals with PAD. A total of 12 participants with PAD underwent training on treadmill for 6 weeks, twice a week, for about 45 minutes. Outcome measures included walking distance (WDI), walking duration (WDU), mean walking rate (WR), estimated oxygen consumption (EVO2), metabolic equivalent (MET), estimated total energy expenditure (ETEE), and estimated rate of energy expenditure (EREE). Mean improvement of WDI, WDU, and MWR were 104% (an addition of 1.0 km), 55% (an addition of 13.3 minutes), and 41% (0.9 km/h faster), respectively. Mean improvement of EVO2, MET, ETEE, and EREE, were 20%, 20%, 80%, and 20%, respectively. In conclusion, it appears that LIPFE training is an effective intervention for individuals presenting with PAD.

Pain-free treadmill exercise for patients with intermittent claudication: Are there gender differences?

Vascular ◽  
2015 ◽  
Vol 24 (3) ◽  
pp. 304-314 ◽  
Author(s):  
Krishna Dipnarine ◽  
Sharon Barak ◽  
Coleen A Martinez ◽  
Eliezer Carmeli ◽  
Christine B Stopka
Keyword(s):  
Peripheral Arterial Disease ◽  
Lower Extremity ◽  
Intermittent Claudication ◽  
Pain Threshold ◽  
Treadmill Exercise ◽  
Arterial Disease ◽  
Walking Distance ◽  
Common Symptom ◽  
Positive Outcomes ◽  
Peripheral Arterial

Intermittent claudication, a common symptom of peripheral arterial disease, results in insufficient blood flow and oxygen supply to lower extremity muscles. Compared to men, women with peripheral arterial disease have a higher rate of mobility loss with peripheral arterial disease due to poorer lower extremity functioning. This study evaluates the effect of supervised pain-free treadmill exercise on improving performance in women with intermittent claudication due to peripheral arterial disease in comparison to men. A total of 26 participants (women, n = 9, 34.62%; mean age = 67.58 ± 5.59 years; averaging 23.46 ± 3.91 visits and 10.46 ± 0.99 weeks in the program) diagnosed with peripheral arterial disease, with symptoms of intermittent claudication, partook in a 45 min treadmill walk, twice per week, below the participant’s minimal pain threshold. Female participants’ change scores showed 752%, 278% and 115% improvement in mean walking distance, duration and rate, respectively. Men improved 334%, 149% and 80%, respectively. Significant differences (p < 0.05) in pre and post measurements within each group support positive outcomes. No significant differences between groups were observed (Cohen’s d effect size > 0.80). Our results suggest that women reap similar benefits from this low-intensity treadmill program in comparison to men.

scholarly journals Treadmill Exercise and Resistance Training in Patients With Peripheral Arterial Disease With and Without Intermittent Claudication

JAMA ◽  
2009 ◽  
Vol 301 (2) ◽  
pp. 165 ◽  
Author(s):  
Mary M. McDermott ◽  
Philip Ades ◽  
Jack M. Guralnik ◽  
Alan Dyer ◽  
Luigi Ferrucci ◽  
...  
Keyword(s):  
Resistance Training ◽  
Peripheral Arterial Disease ◽  
Intermittent Claudication ◽  
Treadmill Exercise ◽  
Arterial Disease ◽  
Peripheral Arterial

scholarly journals Effect of Creatine Supplementation on Functional Capacity and Muscle Oxygen Saturation in Patients with Symptomatic Peripheral Arterial Disease: A Pilot Study of a Randomized, Double-Blind Placebo-Controlled Clinical Trial

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 149
Author(s):  
Wagner Jorge Ribeiro Domingues ◽  
Raphael Mendes Ritti-Dias ◽  
Gabriel Grizzo Cucato ◽  
Nelson Wolosker ◽  
Antônio Eduardo Zerati ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Oxygen Saturation ◽  
Functional Capacity ◽  
Maintenance Phase ◽  
Arterial Disease ◽  
Calf Muscle ◽  
Walking Distance ◽  
Double Blind ◽  
Muscle Oxygen ◽  
Peripheral Arterial

The aim of the study was to verify the effects of creatine (Cr) supplementation on functional capacity (walking capacity; primary outcome) and calf muscle oxygen saturation (StO2) (secondary outcome) in symptomatic peripheral arterial disease (PAD) patients. Twenty-nine patients, of both sexes, were randomized (1:1) in a double-blind manner for administration of placebo (PLA, n = 15) or creatine monohydrate (Cr, n = 14). The supplementation protocol consisted of 20 g/day for 1 week divided into four equal doses (loading phase), followed by single daily doses of 5 g in the subsequent 7 weeks (maintenance phase). Functional capacity (total walking distance) was assessed by the 6 min walk test, and calf muscle StO2 was assessed through near infrared spectroscopy. The measurements were collected before and after loading and after the maintenance phase. The level of significance was p < 0.05. No significant differences were found for function capacity (total walking distance (PLA: pre 389 ± 123 m vs. post loading 413 ± 131 m vs. post maintenance 382 ± 99 m; Cr: pre 373 ± 149 m vs. post loading 390 ± 115 m vs. post maintenance 369 ± 115 m, p = 0.170) and the calf muscle StO2 parameters (p > 0.05). Short- and long-term Cr supplementation does not influence functional capacity and calf muscle StO2 parameters in patients with symptomatic PAD.

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