Delayed Endolymphatic Hydrops

1978 ◽  
Vol 87 (6) ◽  
pp. 743-748 ◽  
Author(s):  
Harold F. Schuknecht
Keyword(s):  
Hearing Loss ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Ménière’S Disease ◽  
Disease Entity ◽  
Profound Hearing Loss ◽  
Episodic Vertigo ◽  
Delayed Endolymphatic Hydrops ◽  
Ménière's Disease ◽  
Fluctuating Hearing Loss

Delayed endolymphatic hydrops is a disease entity that can be differentiated from Meniere's disease. Typically it occurs in patients who have sustained a profound hearing loss in one ear, usually from infection or trauma, and then after a prolonged period of time develop either episodic vertigo from the same ear (ipsilateral delayed endolymphatic hydrops) or fluctuating hearing loss, also sometimes with episodic vertigo, in the opposite ear (contralateral delayed endolymphatic hydrops). The ipsilateral form of the disease may be treated by labyrinthectomy but no satisfactory therapy is available for the contralateral form of the disease.

scholarly journals Meniere Disease: A Case Report

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Edfina Rahmarini ◽  
Hanik Badriyah Hidayati
Keyword(s):  
Hearing Loss ◽  
Meniere’S Disease ◽  
Pharmacological Therapy ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Episodic Vertigo ◽  
Ménière's Disease ◽  
Fluctuating Hearing Loss

Background: Meniere’s disease is a clinical disorder defined as the idiopathic syndrome of endolymphatic hydrops. Meniere’s disease has a prevalence of about 200 cases per 100,000 people in the United States. Prevalence increases linearly with increasing age, especially over 60 years. Men and women are estimated to be proportional in the number of cases. The etiology of Meniere’s disease is currently known to be caused by intrinsic factors and extrinsic factors. Symptoms of Meniere’s disease include recurrent spontaneous episodic vertigo, fluctuating hearing loss, ear fullness, and tinnitus. Treatment of Meniere’s disease can be divided into pharmacological therapy and non-pharmacological therapy. In some cases, complaints can be reduced to 80-90 percent. Case Report: A woman, aged 65 years, complained of constant ringing in her right ear, feeling full and accompanied by decreased hearing in the right ear, spinning dizziness that is not related to changing position, especially when she is tired, ringing in the ear, a feeling of fullness in the ear since 3 months ago. Head MRI results were normal. The patient was treated with HCT 1×50 mg, prednisone 1×80 mg for 7 days, KSR 3×1 tablet, betahistine 2×24 mg. Patients experience improvement in complaints even though the complaints do not disappear completely Conclusion: The diagnosis of Meniere’s disease is established by clinical symptoms, namely recurrent spontaneous episodic vertigo, fluctuating hearing loss, ear fullness, and tinnitus. Appropriate therapy in Meniere’s disease can reduce complaints and improve the patient’s quality of life.

scholarly journals Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear

2019 ◽  
Vol 23 (02) ◽  
pp. 218-220
Author(s):  
Pedro L. Mangabeira Albernaz
Keyword(s):  
Inner Ear ◽  
Carbohydrate Metabolism ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Delayed Endolymphatic Hydrops ◽  
Ménière's Disease

Introduction Menière’s disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an inadequate absorption of the endolymph. A milder type of endolymphatic hydrops results from an altered chemical composition of the endolymph, due to disorders of the carbohydrate metabolism. Objective To describe the association of both types of hydrops in patients with Menière disease. Methods This was a retrospective study of 98 patients with Menière’s disease, 62 of whom also presented disorders of the carbohydrate metabolism, and 5 patients with delayed endolymphatic hydrops, 2 of whom also presented disorders of the carbohydrate metabolism. Results The follow-up of these patients showed that the correction of the metabolic disorders may help in the clinical treatment of Menière’s disease and of delayed endolymphatic hydrops, but this does not happen in the more severe types of the diseases. Conclusion Patients with Menière’s disease may present simultaneous disorders of the carbohydrate metabolism, affecting the inner ear. The correction of these disorders helps the clinical treatment but does not preclude the progression of the more severe cases of Menière disease.

Fluctuating hearing loss in West African and West Indian racial groups: yaws, syphilis or Menière's disease?

1982 ◽  
Vol 96 (9) ◽  
pp. 847-855 ◽  
Author(s):  
R. J. Black ◽  
W. P. R. Gibson ◽  
J. W. R. Capper
Keyword(s):  
Hearing Loss ◽  
Meniere’S Disease ◽  
West African ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Racial Groups ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Fluctuating Hearing Loss

Four cases of fluctuating hearing loss in West African and West Indian racial groups are presented. Two are Menière's disease, and the authors are unaware of any report in English publications describing Menière's disease in these racial groups. One is late syphilitic hearing loss and the other is idiopathic. The possible role of yaws is presented and long-held beliefs questioned.

scholarly journals MENIERE’S DISEASE

2021 ◽  
Vol 2 (1) ◽  
pp. 18-21
Author(s):  
Helena Era Millennie ◽  
Badrul Munir ◽  
Zamroni Afif ◽  
Ria Damayanti ◽  
Shahdevi Nandar Kurniawan
Keyword(s):  
Inner Ear ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Vestibular Evoked Myogenic Potentials ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Episodic Vertigo ◽  
Ménière's Disease

Meniere’s disease is a disorder of the inner ear resulting in symptoms of episodic vertigo, tinnitus, hearing loss and aural pressure. Although the exact etiology is uncertain, it is associated with raised pressure in the endolymph of the inner ear (endolymphatic hydrops). The diagnosis of Meniere's disease is based on the clinical setting of the patient. This disease usually presents with unilateral ear symptoms but can be also bilateral. Meniere's disease attacks are usually random and episodic (approximately 6-11 per year), with periods of remission that can last from months to years. Investigations are audiometry, electronystagmogram, vestibular evoked myogenic potentials (VEMPs) and imaging.The management consist pharmacological and non pharmacological. Meniere's disease is initially progressive but fluctuates unexpectedly. It is difficult to distinguish natural resolutions from treatment effects.

Outcomes in the use of intra-tympanic gentamicin in the treatment of Ménière's disease

2005 ◽  
Vol 120 (2) ◽  
pp. 98-102 ◽  
Author(s):  
Sean Flanagan ◽  
Payal Mukherjee ◽  
John Tonkin
Keyword(s):  
Hearing Loss ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
High Rate ◽  
Response To Treatment ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease

The pathogenesis of Ménière's disease is associated with a disorder of ionic homeostasis, with the pathologic correlate being endolymphatic hydrops. Despite uncertainty as to its particular mode of action, it is accepted wisdom that intra-tympanic gentamicin has a definite therapeutic role in the control of symptoms in patients who fail to respond to medical therapy. This study reports an evaluation of the efficacy of intra-tympanic gentamicin in the treatment of Ménière's disease and also presents a simple, reliable, safe method of administering gentamicin for this purpose.A retrospective review of 56 patients undergoing intra-tympanic gentamicin treatment for Ménière's disease was conducted. Response to treatment was analysed using a patient survey and examination of pure-tone averages. An overall significant improvement in vertigo symptoms of 81.3 per cent was found. There was a 21.4 per cent rate of significant hearing loss, defined as greater than 10 dB, with an average loss in this group of 18.5 dB. A single dose of gentamicin applied directly to the round window resulted in a high rate of control of vertigo, with acceptably low rates of hearing loss.

More drugs for meniere’s disease

1971 ◽  
Vol 9 (11) ◽  
pp. 42-43
Keyword(s):  
Hearing Loss ◽  
Endolymphatic Hydrops ◽  
Meniere’S Disease ◽  
Menière’S Disease ◽  
Meniere's Disease ◽  
Ménière’S Disease ◽  
Menière's Disease ◽  
Ménière's Disease ◽  
Demyelinating Disorders ◽  
Orally Active

Ménière’s syndrome is paroxysmal vertigo with tinnitus and sensorineural (perceptive) hearing loss. The hearing loss may be slowly progressive, fluctuating or sudden. Where no organic cause can be discovered the condition is called Ménière’s disease. The syndrome is found in patients with bone disease involving the otic capsule such as otosclerosis, osteitis deformans or late syphilis. It may also follow labyrinthine trauma or be associated with a wide variety of diseases interfering with the blood supply to the brainstem or inner ear. Endolymphatic hydrops has been demonstrated in all these conditions, and it is believed that it may occur also in Ménière’s disease. Other causes of the syndrome include inflammatory or demyelinating disorders or tumours involving the eighth nerve. Many drugs have been used to treat Ménière’s disease, but with little success. Drugs investigated in recent years include cinnarizine (an antihistamine which has been used for vertigo and motion sickness), betahistine (an orally active histamine analogue) and hydrochlorothiazide.

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