Pretreatment Pathologic Prognostic Factors in Head and Neck Squamous Cell Carcinoma

1997 ◽  
Vol 106 (11) ◽  
pp. 983-988 ◽  
Author(s):  
Kenneth O. Devaney ◽  
Alfio Ferlito ◽  
Brian C. Hunter ◽  
Alessandra Rinaldo

Squamous carcinomas of the head and neck region are a common problem for the otolaryngologist; surgeons are obliged to draw together disparate lines of evidence — from physical examination, pathology, and radiology — to plan optimal therapy for their patients. This article explores some of the ways in which pathologic analysis of a biopsy specimen in the past (determination of extent of invasion and degree of differentiation), present (including an analysis of the pattern of infiltration and the tumor's DNA content), and, perhaps, the future (possibilities including cytogenetics and analysis of discrete steps in the cell cycle) plays a role in this process.

2021 ◽  
Vol 77 (7) ◽  
pp. 700-709
Author(s):  
Naoya Hayashi ◽  
Ryotaro Tokorodani ◽  
Shuji Kenda ◽  
Daisuke Ogasawara ◽  
Fumika Yabe ◽  
...  

1993 ◽  
Vol 107 (12) ◽  
pp. 1171-1173 ◽  
Author(s):  
Izumi Mochimatsu ◽  
Mamoru Tsukuda ◽  
Shigeru Furukawa ◽  
Shuji Sawaki

Metastatic tumours involving the head and neck region are rare. Over the past 18 years, seven such cases were treated at our clinic. Of those, four were in one of the paranasal sinuses, three had arisen from a primary hepatocellular carcinoma and one from an osteogenic fibrosarcoma of the leg. In the remaining three cases, metastases to the larynx, the tonsil, and the parotid gland arose from a primary renal cell carcinoma, a thyroid carcinoma, and a breast carcinoma, respectively. In metastatic tumours, the primary site can often be identified by the histopathological features. Accordingly, when malignant head and neck tumours are suspected of being metastatic in character, it is important to search carefully for the primary site.


Author(s):  
C. J. Timna ◽  
D. Chandrika

<p class="abstract">Benign calcifying epithelioma of Malherbe or pilomatricoma is rare benign skin tumours, typically seen in head and neck region. This is supposed to arise from hair follicle matrix cells. Though head and neck is the commonest area involved by this tumour, only 4.5% cases have been reported in the pinna. Neck is most commonly involved followed by cheek, scalp, pre auricular and peri orbital areas. Here we report a case of pilomatricoma over medial surface of pinna in a 20 years old female. She had the swelling which was gradually increasing for the past 5 years. Histopathological examination following excision biopsy confirmed the diagnosis.</p><p class="abstract"> </p>


1997 ◽  
Vol 106 (6) ◽  
pp. 526-532 ◽  
Author(s):  
Kenneth O. Devaney ◽  
Alfio Ferlito ◽  
Mathew J. Putzi ◽  
Alessandra Rtnaldo

Among the potential sites of involvement by Langerhans cell histiocytosis (LCH), the head and neck region is the most commonly cited. Though principally a pediatric disease, LCH can affect any age group. It can be unifocal (skeletal) or multifocal (skeletal and/or visceral); it appears as though the presence of visceral lesions is more common in the youngest patients, and may be associated in some with a rapidly progressive course resulting in death. Head and neck manifestations may mimic such varied entities as eczema, otitis media, osteomyelitis, and cholesteatoma. Current approaches to therapy are less aggressive than they were in the past, and are particularly intended to monitor for and treat any complicating secondary infections (which may develop in the youngest patients with multifocal disease including visceral involvement). The prognosis is very good for unifocal skeletal system disease, and poor for multifocal disease with involvement of tissues other than bone.


Author(s):  
Jameel N. Alswaiheb ◽  
Mohammad Ali Motiwala ◽  
Muhammad Wasi Ahmed ◽  
Tala Fawwaz Beidas

<p class="abstract">In developing countries, head and neck penetrating injuries from construction nails are rare can be dangerous or fatal. The use of nail guns in the construction industry gained popularity during the 1990s and is now widespread. In majority of nail gun injuries, the extremities are involved, although injuries to the head and neck region have also been described with approximately 45 cases of cranium penetrating nail gun injuries published in the literature. The management of such cases includes a neurological examination, systemic physical examination, and determination of the optimal surgical method to approach and remove the foreign body. we report a case of penetrating skull base injury caused by a nail gun in a 46-year-old man that was successfully managed by a transnasal endoscopic approach. The patient recovered completely and was discharged. To prevent complications and achieve the best outcomes in such cases, careful diagnosis and assessment are necessary.</p>


Author(s):  
Prasetyanugraheni Kreshanti ◽  
Nandya Titania Putri ◽  
Valencia Jane Martin ◽  
Chaula Luthfia Sukasah

Author(s):  
Gonca Cinkara ◽  
Ginger Beau Langbroek ◽  
Chantal M. A. M. van der Horst ◽  
Albert Wolkerstorfer ◽  
Sophie E. R. Horbach ◽  
...  

2021 ◽  
Vol 2021 (4) ◽  
Author(s):  
Geoffrey Williams ◽  
Carlos Neblett ◽  
Jade Arscott ◽  
Sheena McLean ◽  
Shereika Warren ◽  
...  

Abstract Kimura disease (KD) is a chronic, inflammatory, benign disorder endemic to Asia that typically manifests as a triad of painless masses in the head and neck region, elevated eosinophils and serum immunoglobulin. It usually affects young men in their second and third decades of life and is rarely seen outside of the orient. This is a report of a case of KD in a young man of African descent who presented with a cheek mass. KD was not included in our differential diagnosis, and this report highlights the need to consider this entity, which can be easily missed due to its rarity in the Western world. There is no cure for the disease, and management includes medical and surgical modalities, but local recurrence or relapse is not uncommon.


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