Socio-demographic development and burden of mental, substance use disorders, and self-harm: An ecological analysis using the Global Burden of Disease study 2019

2021 ◽  
pp. 000486742110667
Author(s):  
Guillaume Barbalat ◽  
Sze Liu
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Demographic Development ◽  
Disability Adjusted Life ◽  
Geographical Regions ◽  
Self Harm ◽  
Disease Study

Objectives: Whether a country’s level of development is associated with an increased or decreased burden of mental and behavioural problems is an important yet unresolved question. Here, we examined the association between the burden of mental and substance use disorders and self-harm with socio-demographic development along temporal and geographical dimensions. Methods: We collected data from the Global Burden of Disease study 2019, which uses robust statistical modelling techniques to calculate disease burden estimates where data are sparse or unavailable. We extracted age-standardized Disability Adjusted Life Year rates as a measure of disease burden for 204 countries and territories, as well as the Socio-Demographic Index, a measure of development reflecting income per capita, fertility rate and level of education. We tested the association between Socio-Demographic Index and Disability Adjusted Life Years for mental and substance use disorders and self-harm, between 1990 and 2019, and across six geographical regions as defined by the World Health Organization. Results: The association between Socio-Demographic Index and Disability Adjusted Life Years was heterogeneous across world regions for all mental and behavioural conditions. For substance use disorders and self-harm, these regional variations were further moderated by time period. Our findings were robust to down-weighing outlier observations, as well as controlling for other socio-demographic variables, and the number of data sources available in each country. Conclusion: Based on data from the Global Burden of Disease study 2019, we demonstrated that the association between mental and substance use disorders and self-harm with socio-demographic development is dependent on geographical regions and temporal periods. This heterogeneity is likely related to geographical and temporal variations in socio-cultural norms, attitudes towards mental problems, as well as health care and social policies. Better knowledge of this spatial and temporal heterogeneity is crucial to ensure that countries do not develop at the expense of a higher burden of mental and behavioural conditions.

The prevalence and burden of mental and substance use disorders in Australia: Findings from the Global Burden of Disease Study 2015

2018 ◽  
Vol 52 (5) ◽  
pp. 483-490 ◽  
Author(s):  
Liliana G Ciobanu ◽  
Alize J Ferrari ◽  
Holly E Erskine ◽  
Damian F Santomauro ◽  
Fiona J Charlson ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Years Of Life Lost ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Disease Study ◽  
Years Lived With Disability

Objectives: Timely and accurate assessments of disease burden are essential for developing effective national health policies. We used the Global Burden of Disease Study 2015 to examine burden due to mental and substance use disorders in Australia. Methods: For each of the 20 mental and substance use disorders included in Global Burden of Disease Study 2015, systematic reviews of epidemiological data were conducted, and data modelled using a Bayesian meta-regression tool to produce prevalence estimates by age, sex, geography and year. Prevalence for each disorder was then combined with a disorder-specific disability weight to give years lived with disability, as a measure of non-fatal burden. Fatal burden was measured as years of life lost due to premature mortality which were calculated by combining the number of deaths due to a disorder with the life expectancy remaining at the time of death. Disability-adjusted life years were calculated by summing years lived with disability and years of life lost to give a measure of total burden. Uncertainty was calculated around all burden estimates. Results: Mental and substance use disorders were the leading cause of non-fatal burden in Australia in 2015, explaining 24.3% of total years lived with disability, and were the second leading cause of total burden, accounting for 14.6% of total disability-adjusted life years. There was no significant change in the age-standardised disability-adjusted life year rates for mental and substance use disorders from 1990 to 2015. Conclusion: Global Burden of Disease Study 2015 found that mental and substance use disorders were leading contributors to disease burden in Australia. Despite several decades of national reform, the burden of mental and substance use disorders remained largely unchanged between 1990 and 2015. To reduce this burden, effective population-level preventions strategies are required in addition to effective interventions of sufficient duration and coverage.

Mental and substance use disorders in Peru: a systematic analysis of the Global Burden of Disease study

2020 ◽  
Author(s):  
Carlos Alva-Diaz ◽  
Andrely Huerta-Rosario ◽  
Roberto A. Molina ◽  
Kevin Pacheco-Barrios ◽  
Wilfor Aguirre-Quispe ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Systematic Analysis ◽  
Disease Study

scholarly journals The Burden Attributable to Mental and Substance Use Disorders as Risk Factors for Suicide: Findings from the Global Burden of Disease Study 2010

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e91936 ◽  
Author(s):  
Alize J. Ferrari ◽  
Rosana E. Norman ◽  
Greg Freedman ◽  
Amanda J. Baxter ◽  
Jane E. Pirkis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disease Study ◽  
Risk Factors For Suicide

scholarly journals The Global Burden of Mental, Neurological and Substance Use Disorders: An Analysis from the Global Burden of Disease Study 2010

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0116820 ◽  
Author(s):  
Harvey A. Whiteford ◽  
Alize J. Ferrari ◽  
Louisa Degenhardt ◽  
Valery Feigin ◽  
Theo Vos
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disease Study

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

The Lancet ◽  
2013 ◽  
Vol 382 (9904) ◽  
pp. 1575-1586 ◽  
Author(s):  
Harvey A Whiteford ◽  
Louisa Degenhardt ◽  
Jürgen Rehm ◽  
Amanda J Baxter ◽  
Alize J Ferrari ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disease Study

The global burden of mental and substance use disorders

2018 ◽  
pp. 35-44
Author(s):  
Alize J. Ferrari ◽  
Holly E. Erskine ◽  
Fiona J. Charlson ◽  
Damian F. Santomauro ◽  
Janni Leung ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Substance Use ◽  
Substance Use Disorders ◽  
Burden Of Disease ◽  
Health Impacts ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Disease Study ◽  
Over Time

The Global Burden of Disease Study (GBD) uses a scientific framework to quantify health loss due to diseases, injuries, and risk factors by location, age, sex, and year. This work has been central in revealing the global health impacts of mental and substance use disorders. In this chapter, the global burden of mental and substance use disorders, based on findings from the Global Burden of Disease Study 2015 (GBD 2015), is presented. The methods used to estimate the burden of mental and substance use disorders and how that has evolved over time; the key analytical considerations for the accurate interpretation of burden findings; the accessibility of GBD data; and the applicability of GBD data in other areas of public health are summarized.

scholarly journals Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017

2020 ◽  
Vol 26 (Supp 1) ◽  
pp. i12-i26 ◽  
Author(s):  
Juanita A Haagsma ◽  
Spencer L James ◽  
Chris D Castle ◽  
Zachary V Dingels ◽  
Jack T Fox ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Interpersonal Violence ◽  
Development Spectrum ◽  
Global Burden Of Disease ◽  
Global Burden ◽  
Global Pattern ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Self Harm ◽  
Disease Study

BackgroundThe epidemiological transition of non-communicable diseases replacing infectious diseases as the main contributors to disease burden has been well documented in global health literature. Less focus, however, has been given to the relationship between sociodemographic changes and injury. The aim of this study was to examine the association between disability-adjusted life years (DALYs) from injury for 195 countries and territories at different levels along the development spectrum between 1990 and 2017 based on the Global Burden of Disease (GBD) 2017 estimates.MethodsInjury mortality was estimated using the GBD mortality database, corrections for garbage coding and CODEm—the cause of death ensemble modelling tool. Morbidity estimation was based on surveys and inpatient and outpatient data sets for 30 cause-of-injury with 47 nature-of-injury categories each. The Socio-demographic Index (SDI) is a composite indicator that includes lagged income per capita, average educational attainment over age 15 years and total fertility rate.ResultsFor many causes of injury, age-standardised DALY rates declined with increasing SDI, although road injury, interpersonal violence and self-harm did not follow this pattern. Particularly for self-harm opposing patterns were observed in regions with similar SDI levels. For road injuries, this effect was less pronounced.ConclusionsThe overall global pattern is that of declining injury burden with increasing SDI. However, not all injuries follow this pattern, which suggests multiple underlying mechanisms influencing injury DALYs. There is a need for a detailed understanding of these patterns to help to inform national and global efforts to address injury-related health outcomes across the development spectrum.

Sign in / Sign up

Export Citation Format

Share Document