Postoperative Systemic Acyclovir in Juvenile-Onset Recurrent Respiratory Papillomatosis: The Outcome

A prospective observational study was conducted consisting of 21 patients of Juvenile-onset recurrent respiratory papillomatosis, attending the Department of Otorhinolaryngology and Head Neck Surgery at our institution, who underwent surgical excision of the papillomas followed by oral acyclovir postoperatively. The study was aimed to observe the effect of systemic acyclovir on postoperative outcomes in children having recurrent respiratory papillomatosis undergoing primary surgical excision. It was observed that the mean interval between surgeries as well as the number of surgical interventions required was significantly lesser when acyclovir was used as a postoperative adjuvant than when surgery was done alone. Hence, the interval between successive surgeries, or in other words, the time interval between relapse of the disease could be prolonged significantly with the use of postoperative systemic acyclovir. Thus, the disease could be controlled for longer periods and repeated surgeries avoided.

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Hypocalcaemic Tetany After Total Thyroidectomy

Faridpur Medical College Journal ◽

10.3329/fmcj.v10i2.30272 ◽

2016 ◽

Vol 10 (2) ◽

pp. 59-62

Author(s):

Nripendra Nath Biswas ◽

Wazir Ahmed Chaudhury ◽

Jahangir Alam Khan ◽

Akhil Chandra Biswas ◽

Khan Mohammad Arif ◽

...

Keyword(s):

Total Thyroidectomy ◽

Thyroid Function Test ◽

Neck Surgery ◽

Time Interval ◽

College Hospital ◽

Medical College ◽

Post Operative Period ◽

Function Test ◽

Head Neck Surgery ◽

Head Neck

Hypocalcaemic tetany is one the commonest complication after total thyroidectomy. It may cause significant morbidity. Early detection and treatment have better out come. The main objective of the study is to find the incidence of hypcalcaemic tetany in post operative period after total thyroidectomy and average interval period of hypocalcaemia following surgery. This was an observational study conducted in the department of Otolaryngology & head-Neck Surgery Sylhet M.A.G. Osmani Medical College Hospital during 1st January 2006 to 31st December 2007. Pre-operative routine investigation, Thyroid Function test, Ultrasonography thyroid gland and cytological evaluation by FNAC were done in all patients. Ten patient developed hypocalcaemia after surgery. Among them only one suffered from permanent hypocalcaemia. Most of the patient developed symptoms about 48 hours after surgery. The Incidence and time interval of development of hypocalcaemic tetany after total thyroidectomy found in the series fully coincides with the results of other researchers globally.Faridpur Med. Coll. J. Jul 2015;10(2): 59-62

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Evaluation of Post-Hemithyroidectomy hypothyroidism

Bangladesh Journal of Otorhinolaryngology ◽

10.3329/bjo.v26i2.50608 ◽

2020 ◽

Vol 26 (2) ◽

pp. 95-101

Author(s):

SM Abdul Awual ◽

Syeda Marufa Hasan ◽

Suhel Al Muzahid Reza ◽

Md Shahriar Islam ◽

Utpaul Kumar Sarkar ◽

...

Keyword(s):

Risk Factors ◽

Thyroid Function ◽

Neck Surgery ◽

Thyroid Stimulating Hormone ◽

Thyroid Antibodies ◽

Medical College ◽

The Mean ◽

A Prospective Study ◽

Head Neck Surgery ◽

Head Neck

Objective: To evaluate the incidence of post-hemithyroidectomy hypothyroidism and identify possible risk factors that indicates which patients require thyroid function monitoring after surgery. Methods: A prospective study of patients with benign, non-toxic thyroid disease undergoing hemithyroidectomy between January 2017 and July 2019 in the Department of Otolaryngology and Head-Neck Surgery, Sir Salimullah Medical College Mitford Hospital, Dhaka. All patients were in euthyroid state preoperatively.Thyroid specimens were examined for pathological diagnosis and thyroid function was evaluated again six weeks after surgery. Results: All had normal preoperative thyroid function. Six weeks after surgery, 10 (22.22%) of the cases developed hypothyroidism (6.66% overt or symptomatic hypothyroidism and 15.56% subclinical hypothyroidism). The mean preoperative TSH level was significantly higher in the hypothyroid group than in the euthyroid group (2.1±1.1 vs 1.3±0.7mIU/L, p<0.01).Seven of patients with preoperative thyroid stimulating hormone (TSH) level more than or equal to 2 mIU/L developed hypothyroidism in comparison to only 3 of those with preoperative TSH <2 mIU/L (odds ratio 11.3). Conclusion: Ten (22.22%) patients in the present study developed hypothyroidism after hemithyroidectomy. Preoperative TSH more than or equal 2 mIU/L, elevation of thyroid antibodies and thyroiditiswarrant post-operative close TSH monitoring. Awareness of such risk factors for post-operative hypothyroidism would improve patients care and reduce complications. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 95-101

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