scholarly journals A Sweet Voice: Acute Febrile Neutrophilic Dermatosis of the Larynx

2021 ◽  
pp. 014556132110220
Author(s):  
Brian A. Walker ◽  
Lindsey B. Stull ◽  
J. Peyton Hines

Significance Statement Acute febrile neutrophilic dermatosis (Sweet syndrome) is a rare idiopathic condition characterized by fever and whole-body rash of tender erythematous plaques of unknown etiology. Otorhinolaryngologic manifestations of the disease can be severe, yet they are sparsely reported in the literature. We present the first documented case of laryngeal involvement of Sweet syndrome.

1995 ◽  
Vol 14 (2) ◽  
pp. 173-178 ◽  
Author(s):  
W.P. Daniel Su ◽  
Debra L. Fett ◽  
Lawrence E. Gibson ◽  
Mark R. Pittelkow

2021 ◽  
Vol 13 (1) ◽  
pp. 216-221
Author(s):  
Joseph Mishal ◽  
Igor Viner ◽  
Alexandro Livoff ◽  
Shlomo Maayan ◽  
Eli Magen

Syphilis has received its classical designation as one of “the great imitators,” reflecting a wide variety of symptoms and presentations, which can cause difficulties in diagnosis. Here we report an unusual case of secondary syphilis in a person with acute necrotizing tonsillitis and Sweet syndrome. A 33-year-old female presented with fever, bilateral cervical lymphadenopathy, tonsillar enlargements with ulcerated pus-filled lesions on the right tonsil, and multiple pseudovesicular, mammillated, edematous plaques on her neck, face, and extremities. Syphilis serology was positive and a skin biopsy demonstrated a neutrophil-rich dermatitis characteristic of Sweet syndrome. The association of <i>Treponema pallidum</i> infection with Sweet syndrome may be a coincidence; nevertheless, our case serves as a reminder that secondary syphilis should remain in the differential diagnosis of the acute febrile neutrophilic dermatosis.


2017 ◽  
Vol 23 (4) ◽  
Author(s):  
Ashley K Clark ◽  
Annahita K Sarcon ◽  
Maxwell A Fung A Fung ◽  
Thomas Konia ◽  
Erik G Laurin ◽  
...  

2012 ◽  
Vol 16 (2) ◽  
pp. 128-130 ◽  
Author(s):  
Ashley O'toole ◽  
Maureen O'malley

Background: Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membranes. Sweet syndrome is an uncommon reactive neutrophilic dermatosis. Objective: This case report describes the rare presentation of a 58-year-old female patient with newly diagnosed pemphigus vulgaris who later presented with erythematous plaques and leukocytosis highly suggestive of Sweet syndrome. Methods: Review of the literature using the PubMed and Medline databases. Results: The clinical presentation of new-onset Sweet syndrome in a patient with pemphigus has been reported in the literature only on one other occasion. Conclusion: The observation of an association between Sweet syndrome and autoimmune diseases, such as pemphigus vulgaris, may ultimately lead to better understanding of the pathophysiology of this disease.


2009 ◽  
Vol 20 ◽  
pp. S46
Author(s):  
Fatma Alıbaz Öner ◽  
Nesrın Ünalan ◽  
Mehmet Emın Pışkınpaşa ◽  
Mecdı Ergüney

2021 ◽  
Vol 5 (2) ◽  
pp. 174-177
Author(s):  
Zainab Jafri ◽  
Lydia Shedlofsky ◽  
Andrew Newman ◽  
Travis Lam ◽  
Yebabe Mengesha

Acute Febrile Neutrophilic Dermatosis, also known as Sweet Syndrome, is an uncommon inflammatory disorder. Though the exact etiology is unclear, it has been presented in association with various entities. The majority of cases present following upper respiratory infections or viral gastroenteritis. Other causes include drug-induced reactions, pregnancy-related manifestations, or in association with specific hematologic or solid tumors. Rarely, it has been associated with Coccidioidomycosis, a prevalent fungus endemic to the Southwestern regions of the United States with a literature review revealing only three previous cases of Coccidioidomycosis-associated Sweet Syndrome. Here we report two new cases in individuals residing in Arizona.


2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Elgin Hoffmann ◽  
Christian Boßelmann ◽  
Stephan Forchhammer ◽  
Holger Lerche ◽  
Tobias Freilinger

AbstractAcute febrile neutrophilic dermatosis (Sweet‘s syndrome) is a dermatological entity, which may be associated with malignancies, drugs, and infections and which is characterized by high fever, elevated neutrophils, and tender erythematous skin lesions. Involvement of the nervous system – Neuro-Sweet syndrome (NSS) - is rare, manifesting most commonly with an encephalitic syndrome in addition to fever and dermal lesions. Here, we report an unusual case of NSS in a Caucasian male patient in the setting of B-cell-lymphocytosis, with encephalitis preceding dermal lesions. Symptoms resolved completely in response to corticoids.NSS is a rare, but important differential diagnosis in the work-up of febrile aseptic meningoencephalitis unresponsive to anti-infectious treatment. Due to its rarity and clinical variability, diagnosis of NSS might be challenging. Knowledge of this entity may facilitate proper diagnosis and differentiation from conditions with similar clinical presentation, especially Neuro-Behçet‘s disease. It may further lead to early detection of a potentially underlying malignancy and help in initiating adequate therapy.


2019 ◽  
Vol 114 (1) ◽  
pp. S1156-S1156
Author(s):  
Afeefa Shahnawaz ◽  
Sheikh A. Saleem ◽  
Bishnu Sapkota

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