Central Venous Access in the Home Parenteral Nutrition Population–You PICC

2005 ◽  
Vol 29 (6) ◽  
pp. 425-428 ◽  
Author(s):  
Mark H. DeLegge ◽  
Gregory Borak ◽  
Nicole Moore
Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1165 ◽  
Author(s):  
Jessica Noelting ◽  
Brian Jurewitsch ◽  
Johane Allard

Patients on home parenteral nutrition (HPN) are dependent on central venous access for long-term sustenance, and catheter-related bloodstream infections (CRBSIs) are a major cause of morbidity and mortality in this patient population. As such, there is much interest in finding new methods for preventing CRBSIs in patients on HPN. As it is thought that these infections are preceded by microbial colonization of the catheter, one approach is to use antimicrobial catheter lock solutions. Although antibiotic catheter lock solutions have been present for decades, their use has been mostly limited to the treatment of CRBSIs due to concern for promoting microbial resistance. Recently, however, with the advent of non-antibiotic antimicrobial catheter lock solutions, this approach is gaining popularity as a promising method to decrease rates of CRBSI in HPN patients.


2020 ◽  
pp. 112972982094691
Author(s):  
Jocelyn Hill ◽  
Rachel Garner

Introduction: A functioning and reliable central venous access device is fundamental for home parenteral nutrition patients to administer essential nutrition. Complications of central venous access devices including occlusion, microbial colonization, and biofilm formation are problematic and sometimes life-threatening. A novel lock solution, 4% tetrasodium ethylenediaminetetraacetic acid, has properties that may reduce such complications. Purpose: The aim of this study was to determine the safety, efficacy, and cost implications of implementing 4% tetrasodium ethylenediaminetetraacetic acid to prevent catheter-related complications in home parenteral nutrition patients. Methods: A pre- and post-intervention study was carried over 36 months (12 months pre; 24 months post) by the British Columbia Home Parenteral Nutrition Program in Vancouver, Canada, where 4% tetrasodium ethylenediaminetetraacetic acid was implemented for patients at high risk for central venous access device occlusion and catheter-related infection. Patients were included in the study if they had previous central venous access device complications. The outcomes evaluated were central line-associated bloodstream infection, catheter occlusion requiring thrombolytic treatment, and catheter replacements. Results: In total, 22 out of 105 patients met the inclusion criteria. Two patients were excluded from analyses due to non-adherence and concomitant use of other lock solutions. Post intervention, 20 home parenteral nutrition patients experienced significant reduction in the central line-associated bloodstream infection rate (pre = 1.918/1000 catheter days; post = 0.563/1000 catheter days; p = 0.04) There were no occlusion events reported post intervention. Conclusion: For home parenteral nutrition patients, 4% tetrasodium ethylenediaminetetraacetic acid lock solution effectively reduces the risk of central venous access device complications including occlusions and catheter-related infections.


2007 ◽  
Vol 31 (5) ◽  
pp. 382-387 ◽  
Author(s):  
Robert DeChicco ◽  
Douglas L. Seidner ◽  
Carlos Brun ◽  
Ezra Steiger ◽  
Judy Stafford ◽  
...  

2020 ◽  
Vol 25 (7) ◽  
pp. 1-4
Author(s):  
Delphine Le Chevallier

Placing a central venous jugular catheter is a valuable technique. The method used is the modified Seldinger technique (over the wire), which is also used to place chest drains. While intravenous catheterisation of a peripheral vein is common practice in veterinary medicine, critically ill patients may require central venous access if peripheral access is not possible. This is also useful when large volumes of fluid are required, for example for administration of irritant drugs or for parenteral nutrition, or for regular blood sampling.


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