Acoustic Radiation Force Impulse (ARFI) Imaging of the Gastrointestinal Tract

2005 ◽  
Vol 27 (2) ◽  
pp. 75-88 ◽  
Author(s):  
Mark L. Palmeri ◽  
Kristin D. Frinkley ◽  
Liang Zhai ◽  
Marcia Gottfried ◽  
Rex C. Bentley ◽  
...  
Keyword(s):  
Radiation Treatment ◽  
Acoustic Radiation ◽  
Ex Vivo ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
High Intensity Focused Ultrasound ◽  
Acoustic Radiation Force Impulse ◽  
Gi Tract ◽  
Small Bowel Tumors ◽  
Arfi Imaging

The evaluation of lesions in the gastrointestinal (GI) tract using ultrasound can suffer from poor contrast between healthy and diseased tissue. Acoustic Radiation Force Impulse (ARFI) imaging provides information about the mechanical properties of tissue using brief, high-intensity, focused ultrasound to generate radiation force and ultrasonic correlation-based methods to track the resulting tissue displacement. Using conventional linear arrays, ARFI imaging has shown improved contrast over B-mode images when applied to solid masses in the breast and liver. The purpose of this work is to (1) investigate the potential for ARFI imaging to provide improvements over conventional B-mode imaging of GI lesions and (2) demonstrate that ARFI imaging can be performed with an endocavity probe. ARFI images of an adenocarcinoma of the gastroesophageal (GE) junction, status-post chemotherapy and radiation treatment, demonstrate better contrast between healthy and fibrotic/malignant tissue than standard B-mode images. ARFI images of healthy gastric, esophageal, and colonic tissue specimens differentiate normal anatomic tissue layers (i.e., mucosal, muscularis and adventitial layers), as confirmed by histologic evaluation. ARFI imaging of ex vivo colon and small bowel tumors portray interesting contrast and structure that are not as well defined in B-mode images. An endocavity probe created ARFI images to a depth of over 2 cm in tissue-mimicking phantoms, with maximum displacements of 4 μm. These findings support the clinical feasibility of endocavity ARFI imaging to guide diagnosis and staging of disease processes in the GI tract.

Observations of Tissue Response to Acoustic Radiation Force: Opportunities for Imaging

2002 ◽  
Vol 24 (3) ◽  
pp. 129-138 ◽  
Author(s):  
Kathryn Nightingale ◽  
Rex Bentley ◽  
Gregg Trahey
Keyword(s):  
Acoustic Radiation ◽  
Ex Vivo ◽  
Ultrasonic Transducer ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Tissue Response ◽  
Acoustic Radiation Force Impulse ◽  
Ex Vivo Tissues ◽  
Force Excitation ◽  
Arfi Imaging

Acoustic Radiation Force Impulse (ARFI) imaging is a method for characterizing local variations in tissue mechanical properties. In this method, a single ultrasonic transducer array is used to both apply temporally short localized radiation forces within tissue and to track the resulting displacements through time. In an ongoing study of the response of tissue to temporally short radiation force excitation, ARFI datasets have been obtained of ex vivo tissues under various focal configurations. The goal of this paper is to report observations of the response of tissue to radiation force and discuss the implications of these results in the construction of clinical imaging devices.

Breast Lesions Evaluated by Color-Coded Acoustic Radiation Force Impulse (ARFI) Imaging

2016 ◽  
Vol 42 (7) ◽  
pp. 1464-1472 ◽  
Author(s):  
JianQiao Zhou ◽  
ZhiFang Yang ◽  
WeiWei Zhan ◽  
JingWen Zhang ◽  
Na Hu ◽  
...  
Keyword(s):  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Breast Lesions ◽  
Arfi Imaging

Clinical application of Acoustic Radiation Force Impulse Imaging with Virtual Touch IQ in breast ultrasound: diagnostic performance and reproducibility of a new technique

2016 ◽  
Vol 58 (2) ◽  
pp. 140-147 ◽  
Author(s):  
Panagiotis Kapetas ◽  
Katja Pinker-Domenig ◽  
Ramona Woitek ◽  
Paola Clauser ◽  
Maria Bernathova ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Clinical Setting ◽  
Diagnostic Performance ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Breast Lesions ◽  
Cutoff Value ◽  
Arfi Imaging

Background Virtual Touch IQ (VTIQ) is a novel technique of quantitative sonoelastography that applies acoustic radiation force impulse (ARFI). Purpose To evaluate breast ARFI imaging with VTIQ in the clinical setting, with regard to reproducibility and diagnostic performance, and to specify cutoff limits for the differentiation of benign and malignant lesions. Material and Methods This retrospective study included 83 patients with 85 breast lesions (51 benign, 34 malignant) who received ARFI imaging with VTIQ. Two independent ARFI measurements of each lesion were performed and shear wave velocities (SWV) of the lesion and the adjacent tissues were measured. A lesion-to-fat velocity ratio (L/F Ratio) was calculated for each lesion. Diagnostic performance of SWV measurements and L/F Ratios was evaluated with receiver operating curve (ROC) analysis. The intraclass correlation coefficient and Bland–Altman plots were used to evaluate measurement reproducibility. Results All measurements showed equal diagnostic performance, as measured by the area under the ROC curve (0.853 for SWV, 0.882 for the L/F Ratio). At a cutoff value of 3.23 m/s, sensitivity and specificity were 82.4% and 80.4%, respectively. An L/F Ratio cutoff value of 2.23 revealed a sensitivity and specificity of 89.7% and 76.5%. The reproducibility of the SWV measurements was moderate (limits of agreement, 40.3–44.4%) and higher than that of the L/F Ratios (54.5–60.2%). Conclusion ARFI imaging with VTIQ is a novel, moderately reproducible, quantitative elastography technique, which provides useful information for the differentiation of benign and malignant breast lesions in the clinical setting.

Acoustic Radiation Force Impulse (ARFI) imaging for the distinction between benign and malignant thyroid nodules

2015 ◽  
Vol 120 (6) ◽  
pp. 579-583 ◽  
Author(s):  
Cihad Hamidi ◽  
Cemil Göya ◽  
Salih Hattapoğlu ◽  
Ömer Uslukaya ◽  
Memik Teke ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
Arfi Imaging

scholarly journals Role of Ultrasound Acoustic Radiation Force Impulse in Differentiating Benign from Malignant Superficial Lymph Nodes

2020 ◽  
Vol 10 ◽  
pp. 18
Author(s):  
Reettika Chanda ◽  
Madhavi Kandagaddala ◽  
Vinu Moses ◽  
Elanthenral Sigamani ◽  
Shyamkumar Nidugala Keshava ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Diagnostic Performance ◽  
Acoustic Radiation ◽  
Radiation Force ◽  
Area Ratio ◽  
Acoustic Radiation Force ◽  
Acoustic Radiation Force Impulse ◽  
The Mean ◽  
Malignant Lymph Nodes ◽  
Arfi Imaging

Objective: The purpose of this study was to evaluate the diagnostic performance of acoustic radiation force impulse (ARFI) imaging in differentiating benign from malignant peripheral lymphadenopathy. Materials and Methods: This was a prospective study approved by the Institutional Review Board with financial grant for the same. Ultrasound and ARFI imaging of peripheral lymph nodes were performed and correlated with pathological results, which were used as the reference standard. The virtual touch tissue imaging and virtual touch tissue quantification parameters of ARFI were analyzed in 86 lymph nodes, of which 78 were included in the study. Using receiver operating characteristic curve analysis, the diagnostic usefulness of ARFI values were evaluated with respect to their sensitivity, specificity, and area under the curve. Results: The mean area ratio of benign lymph nodes was 0.88 (±0.2) and that of malignant lymph nodes was 1.17 (±0.14). The mean shear wave velocities (SWV) of benign and malignant lymph nodes were 2.02 m/s (±0.94) and 3.7 m/s (±2.27), respectively. The sensitivity and specificity of virtual touch imaging area ratio in differentiating benign from malignant lymph nodes was 97% and 77%, of SWV was 71% and 70%, and of SWV ratio was 68% and 79%, respectively. Conclusion: As ARFI was found to have a superior diagnostic performance over conventional ultrasound and color Doppler in the characterization of lymph nodes, we recommend its routine use in differentiating benign from malignant nodes.

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