Reserpine-Induced Complete Heart Block

1998 ◽  
Vol 6 (1) ◽  
pp. 64-65
Author(s):  
Mandeep Singh ◽  
Manoj Kumar Agarwala ◽  
Rajnish Juneja

Reserpine is an adrenergic neuron blocking agent that acts by depleting the stores of catecholamines. Its use as an antihypertensive has declined recently because of frequent undesirable side-effects. The side-effects are primarily extracardiac and occur at high dosages. Cardiovascular side-effects are rare and include a decrease in atrioventricular conduction, potentiation of digitalis toxicity, and possible precipitation of ventricular ectopics. We report a case of reseprine-induced complete heart block requiring a temporary pacemaker for a few days.

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 1243
Author(s):  
Andrianto Andrianto ◽  
Eka Prasetya Budi Mulia ◽  
Denny Suwanto ◽  
Dita Aulia Rachmi ◽  
Mohammad Yogiarto

Metastatic tumors of the heart presenting with complete heart block (CHB) is an extremely uncommon case. There are no available guidelines in managing CHB in terminal cancer. Permanent pacemaker implantation in such cases is a challenge in terms of clinical utility and palliative care. We report a case of a 24-year-old man suffering from tongue cancer presenting with CHB. An intracardiac mass and moderate pericardial effusion were present, presumed as the metastatic tumor of tongue cancer. We implanted a temporary pacemaker for his symptomatic heart block and cardiogenic shock, and pericardiocentesis for his massive pericardial effusion. We decided that a permanent pacemaker would not be implanted based on the low survival rate and significant comorbidities. Multiple studies report a variable number of cardiac metastasis incidence ranging from 2.3% to 18.3%. It is rare for such malignancies to present with CHB. The decision to implant a permanent pacemaker is highly specific based on the risks and benefits of each patient. It needs to be tailored to the patient’s functional status, comorbid diseases, prognosis, and response to conservative management.


Author(s):  
Nurul Iftida Basri ◽  
Shuhaila Ahmad

Abstract Complete heart block (CHB) is infrequently encountered during pregnancy. Its management requires a multidisciplinary approach involving the obstetrician, cardiologist, anesthetist and neonatologist. It varies from conservative, temporary or permanent pacemaker (PPM) insertion (either during the antenatal, intrapartum or postpartum period). We present the case of a 30-year-old, gravida 2 para 1 at the 36-week period of amenorrhea (POA) with congenital CHB. She was asymptomatic throughout her pregnancy despite having a pulse rate between 40 and 50 beats per minute. She delivered a healthy boy via cesarean section due to breech presentation after a failed external cephalic version. A temporary pacemaker was inserted prior to delivery. However, she required permanent insertion of pacemaker during the postpartum period.


2017 ◽  
Vol 02 (02) ◽  
pp. 042-045
Author(s):  
K. Prasad ◽  
K. Lavanya

AbstractCardiac glycosides are widely available in botanic products and other naturally occurring substances worldwide. Accidental consumption of it leads to digitalis toxicity with varied systemic manifestations. We describe a case of consumption of extract of leaves of the Indian rubber vine plant (Crytostegia grandi flora) which led to gastrointestinal, cardiac, electrolyte, and hematological disturbances.


Author(s):  
Dhanang Ali Yafi ◽  
Cloudia Noviani ◽  
Rahmi Eka Saputri ◽  
Adi Purnawarman ◽  
Mohd. Andalas ◽  
...  

Background: Complete heart block occurs due to various pathological conditions that cause an infiltration, fibrosis, or lose the connection from a part of the cardiac conduction system. Complete heart  block in pregnancy is often caused by congenital anomalies. Around 30% cases, complete heart block remain asymptomatic and not detected until adulthood and may present in pregnancy state and puerperium. When the reversible cause of the AV Block cannot be found, the permanent pacemaker or temporary pacemaker may be indicated when the patients show the symptoms. Case Illusration: A-21 year old female, G2P0A1 preterm pregnancy (27-28 weeks) with bradycardia. From electrocardiograph examination revealed Total AV Block with junctional escape rhytym. Transthoracic echocardiogram shows massive tricuspid regurgitation, early phase of peripartum cardiomyopathy and ejection fraction 36-40%. Caesarean section was peformed due to PPROM. A male baby was born with birth weight of 1100 grams, 32 centimeters of body length and APGAR score of 7/9. The baby was died in NICU on day care 4th, with suspected respiratory problem. Conclusion: Complete heart block in pregnancy is a rare condition. This condition could remain asymptomatic and not detected until pregnancy. Multidisciplinary approach, close monitoring of the symptoms and cardiac functions are needed for patients with CHB.


1982 ◽  
Vol 75 (5) ◽  
pp. 601-603 ◽  
Author(s):  
MARTIN A. ALPERT ◽  
JAY D. DIX ◽  
PETER C. HAMEL ◽  
LIEM C. VU

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Jan M. Van Keer

Background. Cannabis (marijuana) is the most widely consumed illicit drug in Europe. However, many are unaware of its potential cardiovascular side effects. Case Report. A 19-year-old man presented to the emergency department with palpitations and presyncope after smoking cannabis. A third-degree atrioventricular block (complete heart block) was diagnosed. We believe cannabis exposure to have been the likely cause. Extensive work-up—including Borrelia and auto-immune serology, CT coronary angiography, magnetic resonance imaging, and electrophysiological study—was negative. The patient was initially treated with IV isoprenaline. Within one day, the bradycardia spontaneously resolved. The patient was advised to quit using cannabis. No further therapy was initiated. We discuss the clinical presentation, pathophysiology, and evidence from the literature linking cannabis exposure to bradycardia. Conclusion. We describe a case of third-degree atrioventricular block after cannabis use. Emergency physicians should be aware of the potential cardiovascular side effects of this drug.


2017 ◽  
Vol 13 (4) ◽  
pp. 372-374 ◽  
Author(s):  
L. Dubey ◽  
S. Guruprasad ◽  
R. Battacharya ◽  
G. Subramanyam

Ventricular tachyarrhythmias are common in hypertrophic cardiomyopathy that may lead to syncope and sudden death. Bradyarrhythmia such as atrioventricular conduction disturbance, a relatively rare complication associated with hypertrophic cardiomyopathy, may also cause syncope and sudden death in hypertrophic cardiomyopathy. We report a 28-year old man who was diagnosed as a case of hypertrophic cardiomyopathy presented with syncope and complete heart block. Subsequently, a permanent pacemaker was implanted to the patient.


Heart Rhythm ◽  
2017 ◽  
Vol 14 (12) ◽  
pp. 1786-1792 ◽  
Author(s):  
Erich L. Kiehl ◽  
Tarek Makki ◽  
Ralph M. Matar ◽  
Douglas R. Johnston ◽  
John W. Rickard ◽  
...  

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