A Perspective on Tests Predicting Chemical Mutagens/Carcinogens in Man

1982 ◽  
Vol 10 (2) ◽  
pp. 44-69
Author(s):  
Diana Anderson
Keyword(s):  
Chemical Mutagens

scholarly journals THIRD-CHROMOSOME MUTAGEN-SENSITIVE MUTANTS OF DROSOPHILA MELANOGASTER

Genetics ◽  
1981 ◽  
Vol 97 (3-4) ◽  
pp. 607-623 ◽  
Author(s):  
J B Boyd ◽  
M D Golino ◽  
K E S Shaw ◽  
C J Osgood ◽  
M M Green
Keyword(s):  
Drosophila Melanogaster ◽  
Genetic Map ◽  
Nitrogen Mustard ◽  
Chromosome 3 ◽  
Methyl Methanesulfonate ◽  
Dna Metabolism ◽  
Genetic Analyses ◽  
Chemical Mutagens ◽  
Complementation Groups ◽  
Biochemical Analyses

ABSTRACT A total of 34 third chromosomes of Drosophila melanogaster that render homozygous larvae hypersensitive to killing by chemical mutagens have been isolated. Genetic analyses have placed responsible mutations in more than eleven complementation groups. Mutants in three complementation groups are strongly sensitive to methyl methanesulfonate, those in one are sensitive to nitrogen mustard, and mutants in six groups are hypersensitive to both mutagens. Eight of the ten loci mapped fall within 15% of the genetic map that encompasses the centromere of chromosome 3. Mutants from four of the complementation groups are associated with moderate to strong meiotic effects in females. Preliminary biochemical analyses have implicated seven of these loci in DNA metabolism.

scholarly journals Suppression of SOS-Inducing Activity of Chemical Mutagens by Yakuchinone A from Alpinia oxyphylla in the Salmonella typhimurium TA1535/pSK1002 umu Test.

2001 ◽  
Vol 50 (6) ◽  
pp. 485-489
Author(s):  
Mitsuo MIYAZAWA ◽  
Yuji NAKAMURA ◽  
Katsuhisa SAKANO ◽  
Sei-ichi NAKAMURA ◽  
Hiroshi KOSAKA
Keyword(s):  
Salmonella Typhimurium ◽  
Chemical Mutagens ◽  
Alpinia Oxyphylla ◽  
Umu Test ◽  
Yakuchinone A

Weakening of DNA-protein interaction in cultured human fibroblasts induced by chemical mutagens

1987 ◽  
Vol 104 (6) ◽  
pp. 1730-1732
Author(s):  
A. I. Gorin ◽  
N. S. Bogomolova ◽  
A. V. Ermakov ◽  
M. I. Freidin ◽  
V. A. Chernov ◽  
...  
Keyword(s):  
Protein Interaction ◽  
Human Fibroblasts ◽  
Chemical Mutagens ◽  
Cultured Human Fibroblasts ◽  
Dna Protein Interaction

Novel Wx alleles induced by chemical mutagens in rice, Oryza sativa L.

2017 ◽  
Vol 136 (2) ◽  
pp. 206-213 ◽  
Author(s):  
Bing-nan Lin ◽  
Yu-chia Hsu ◽  
Su-chen Kuo ◽  
Yann-rong Lin ◽  
Yong-pei Wu ◽  
...  
Keyword(s):  
Oryza Sativa ◽  
Oryza Sativa L ◽  
Chemical Mutagens

Effects of chemical mutagens on the physio-chemical traits of Tomato (Lycopersicon esculentum)

2021 ◽  
Vol 9 (2) ◽  
pp. 62-67
Author(s):  
L Tripathy ◽  
S Srichandan ◽  
SK Dash ◽  
J Bhuyan ◽  
T R Sahoo
Keyword(s):  
Lycopersicon Esculentum ◽  
Chemical Mutagens ◽  
Chemical Traits
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