Effects of cardiopulmonary bypass on systemic vascular resistance

Perfusion ◽  
1996 ◽  
Vol 11 (4) ◽  
pp. 346-350 ◽  
Author(s):  
Pca Kam ◽  
L. Hines ◽  
E. O'Connor
Keyword(s):  
Cardiopulmonary Bypass ◽  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Systemic Vascular Resistance ◽  
Vascular Resistance ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Haemodynamic Changes ◽  
Neuroendocrine Responses

During cardiopulmonary bypass (CPB), complex neuroendocrine responses occur and result in haemodynamic changes. Systemic vascular resistance (SVR) before, during, and after CPB was documented in patients undergoing coronary artery bypass surgery. Whilst the overall effect was an increased SVR, transient profound decreases in SVR at the commencement of CPB, during the rewarming phase, and immediately on weaning off CPB were demonstrated.

Effects of Intravenous Triiodothyronine during Coronary Artery Bypass Surgery

2002 ◽  
Vol 10 (3) ◽  
pp. 219-222 ◽  
Author(s):  
Mustafa Güden ◽  
Belhhan Akpinar ◽  
Ertan Sagğbaş ◽  
İlhan Sanisoğlu ◽  
Emine Cakali ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Systemic Vascular Resistance ◽  
Vascular Resistance ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Double Blind Study ◽  
Group A ◽  
Group B

A prospective randomized and double-blind study was performed to evaluate whether perioperative triiodothyronine administration has any effect on cardiovascular performance after coronary artery bypass surgery. Sixty patients were assigned to 2 groups of 30 each. When crossclamping ended, group A received an intravenous bolus of triiodothyronine, followed by infusion for 6 hours. Group B received a placebo. Serum triiodothyronine levels and hemo-dynamic parameters were serially measured. Mean postoperative cardiac index was slightly, but not significantly, higher in group A, whereas systemic vascular resistance was significantly lower in group A. Compared with preoperative values, serum triiodothyronine levels dropped significantly in group B at the end of cardiopulmonary bypass and remained low 12 hours postoperatively, while levels rose significantly in group A. No significant differences were detected between the groups in the incidence of arrhythmia, the need for inotropic support, intensive care unit stay, mortality, and morbidity. Perioperative administration of triiodothyronine increased cardiac output slightly and decreased systemic vascular resistance, but it had no effect on operative outcome. Routine use after coronary surgery is thus not recommended.

Miniaturized versus conventional cardiopulmonary bypass in high-risk patients undergoing coronary artery bypass surgery

Perfusion ◽  
2010 ◽  
Vol 25 (2) ◽  
pp. 65-70 ◽  
Author(s):  
Simo-Pekka Koivisto ◽  
Jan-Ola Wistbacka ◽  
Riikka Rimpiläinen ◽  
Juha Nissinen ◽  
Pertti Loponen ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Coronary Artery ◽  
High Risk ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
High Risk Patients ◽  
Risk Patients
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