Evidence for orthopaedic surgery in the treatment of metastatic bone disease of the extremities: A review article

2011 ◽  
Vol 26 (6) ◽  
pp. 788-796 ◽  
Author(s):  
Ajay Malviya ◽  
Craig Gerrand
Keyword(s):  
Bone Disease ◽  
Orthopaedic Surgery ◽  
Review Article ◽  
Metastatic Bone Disease

Orthopaedic surgery in the palliation of cancer

2021 ◽  
pp. 839-848
Author(s):  
Mohamed Yakoub ◽  
John Healey
Keyword(s):  
Bone Disease ◽  
Chronic Condition ◽  
Orthopaedic Surgery ◽  
Functional Limitation ◽  
Metastatic Bone Disease ◽  
Site Specific ◽  
Pain Disability ◽  
Targeted Drug ◽  
Surgical Treatments ◽  
Targeted Drug Therapies

Metastatic spread of cancer to bone is frequent and causes pain, disability, and functional limitation. Non-surgical treatments such as chemotherapy and hormone therapy are effective in early disease. Administration of bisphosphonates or osteoprotegerin inhibitors prevent new ‘bone events’, thereby avoiding pain, radiation, and surgery. Radiotherapy arrests disease and relieves pain in many cases. Surgery is needed when the bone is weak or fractured. It effectively relieves pain and preserves function by bypassing the deficient bone with site-specific reconstructive surgery. Surgery should be selected based on projections of patient survival. New tools to make these projections are now available (https://www.pathfx.org/). New targeted drug therapies appear to be changing metastatic bone disease into a more chronic condition. This will alter the management of local disease in many histological subtypes of metastatic cancers.

Metastatic bone disease in patients with neuroendocrine tumors

2014 ◽  
Author(s):  
Krystallenia Alexandraki ◽  
Maria Chrysochoou ◽  
Maria Kaltsatou ◽  
Eleftherios Chatzellis ◽  
Marina Tsoli ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Bone Disease ◽  
Metastatic Bone Disease

scholarly journals Surgical Treatment of Metastatic Bone Disease—When Decisions at End-of-Life Really Makes the Difference

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2581
Author(s):  
Michala Skovlund Sørensen ◽  
Michael Mørk Petersen
Keyword(s):  
Surgical Treatment ◽  
End Of Life ◽  
Bone Disease ◽  
Paradigm Shift ◽  
Metastatic Bone Disease ◽  
The Difference

The current era within the field of surgical treatment of metastatic bone disease (MBD) is best described as the beginning of a paradigm shift [...]

Use of Dichloromethylene Diphosphonate in Metastatic Bone Disease

1983 ◽  
Vol 308 (25) ◽  
pp. 1499-1501 ◽  
Author(s):  
André Jung ◽  
Alex Chantraine ◽  
Alfred Donath ◽  
Christiana van Ouwenaller ◽  
Dora Turnill ◽  
...  
Keyword(s):  
Bone Disease ◽  
Metastatic Bone Disease ◽  
Dichloromethylene Diphosphonate

Metastatic Bone Disease

2003 ◽  
Vol 2 (4) ◽  
pp. 269-281 ◽  
Author(s):  
Janet E Brown ◽  
Robert E Coleman
Keyword(s):  
Bone Disease ◽  
Metastatic Bone Disease
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