Rhabdomyosarcoma of the Petrous Ridge

The CT and MR findings are reported in a case of biopsy proven rhabdomyosarcoma of the skull base. The tumor presumably originated in a pneumatized petrous ridge and had an atypical presentation of multiple cranial nerve palsy. The lesion exhibited a soft tissue density and a nonexpansile bone destruction on unenhanced CT. On MR imaging the lesion showed homogeneous intermediate signal intensity on T1 weighted images and a high signal intensity on proton density and T2 weighted images. The scanty literature on CT and MR features of rhabdomyosarcoma of the head and neck is reviewed.

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Case 13.16

Mayo Clinic Body MRI Case Review ◽

10.1093/med/9780199915705.003.0340 ◽

2014 ◽

pp. 643-644

Author(s):

Christine U. Lee ◽

James F. Glockner

Keyword(s):

Coronary Artery Disease ◽

Coronary Artery ◽

Signal Intensity ◽

Left Atrial ◽

Interatrial Septum ◽

High Signal Intensity ◽

High Signal ◽

Proton Density ◽

Cine Ssfp ◽

Artery Disease

72-year-old woman with known coronary artery disease; echocardiography noted a possible left atrial mass, and MRI was suggested for further assessment Horizontal long-axis images from a cine SSFP acquisition (Figure 13.16.1) demonstrate dumbbell-shaped widening of the interatrial septum with uniform high signal intensity. Axial double inversion recovery FSE proton density-weighted images (...

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Magnetic resonance imaging of the normal dromedary camel tarsus

10.21203/rs.3.rs-35513/v2 ◽

2020 ◽

Author(s):

Usama Hagag ◽

Zakriya Ali Almohamad ◽

Mohamed Gomaa Tawfiek ◽

Ayman El Nahas

Keyword(s):

Magnetic Resonance Imaging ◽

Articular Cartilage ◽

Magnetic Resonance ◽

Signal Intensity ◽

High Signal ◽

Proton Density ◽

Dromedary Camel ◽

Resonance Imaging ◽

Intermediate Signal Intensity ◽

Tarsal Bones

Abstract Background: Magnetic resonance imaging (MRI) is the most versatile and informative imaging modality for the diagnosis of locomotor injuries in many animal species; however, veterinary literature describing the MRI of the dromedary camel tarsus is lacking. Our purpose was to describe and compare the MRI images of twelve cadaveric tarsi, examined in a 1.5 Tesla MRI scanner, with their corresponding anatomical gross sections. Turbo spin-echo (TSE) T1-weighted (T1), T2-weighted (T2), proton density-weighted (PD), and short tau inversion recovery (STIR) sequences were obtained in 3 planes. Tarsi were sectioned in sagittal, dorsal, and transverse planes. MRI images from different sequences and planes were described and compared with the anatomical sections.Results: The soft and osseous tissues of the dromedary camel tarsus corresponded extensively with the gross anatomic sections. T1 and PD images provided high anatomical details and the synovial fluid had high signal intensity on T2, PD, and STIR sequences and intermediate signal intensity on T1 images. The tibial cochlea, tarsal bones, and the proximal metatarsus were evaluated in all planes. The sagittal and dorsal images were useful for the evaluation of articular cartilage and subchondral bone. Articular cartilage had homogenous intermediate signal intensity on the T1 images and low signal intensity on the T2 and PD images. The Subchondral and cortical bone had low signal intensity on all sequences, and the cancellous bone expressed heterogeneous signal intensity on PD, T1, and T2 images. The tarsal tendons and ligaments had low signal intensity in all sequences including: the tendons of fibularis tertius, long digital extensor, cranial tibial, fibularis longus, lateral digital extensor muscles; the common tendon of the caudal tibial and lateral digital flexor muscles; the medial digital flexor tendon; the long and short bundles of the medial and lateral collateral ligaments; the superficial and deep digital flexor tendons; and the long plantar ligament. Conclusions: MRI images provided a thorough evaluation of the normal dromedary camel tarsus. Information provided in the current study is expected to serve as a basis for interpretation in clinical situations.

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The joint involvement in adult onset Still's disease is characterised by a peculiar magnetic resonance imaging and a specific transcriptomic profile

Scientific Reports ◽

10.1038/s41598-021-91613-5 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Piero Ruscitti ◽

Antonio Barile ◽

Onorina Berardicurti ◽

Sonia Iafrate ◽

Paola Di Benedetto ◽

...

Keyword(s):

Signal Intensity ◽

Clinical Characteristics ◽

High Signal Intensity ◽

Adult Onset Still’S Disease ◽

Joint Involvement ◽

High Signal ◽

Bone Erosions ◽

Transcriptomic Profile ◽

Synovial Tissues ◽

Bone Oedema

AbstractAdult onset Still's disease (AOSD) is a rare systemic autoinflammatory disease, characterised by fever, arthritis, and skin rash, and joint involvement is one of its clinical manifestations. The aims of this work were to assess joint involvement, to describe main patterns of involvement, and associated clinical characteristics. In this work, we aimed at assessing the joint involvement in AOSD by using MRI, to describe main patterns and associated clinical characteristics. In addition, we aimed at assessing the global transcriptomic profile of synovial tissues in AOSD to elucidate possible pathogenic pathways involved. We also evaluated the global transcriptomic profile of synovial tissues to elucidate possible pathogenic pathways involved in the disease. Thus, AOSD patients, who underwent to MRI exam on joints, were assessed to describe patterns of joint involvement and associated clinical characteristics. Some synovial tissues were collected for RNA-sequencing purposes. The most common MRI finding was the presence of synovitis on 60.5%, mainly in peripheral affected joints, with low to intermediate signal intensity on T1-weighted images and intermediate to high signal intensity on T2-fat-saturated weighted and STIR images. Bone oedema and MRI-bone erosions were reported on 34.9% and 25.6% MRI exams, respectively. Patients with MRI-bone erosions showed a higher prevalence of splenomegaly, a more frequent chronic disease course, lower levels of erythrocyte sedimentation rate, and ferritin. In AOSD synovial tissues, a hyper-expression of interleukin (IL)-1, IL-6, and TNF pathways was shown together with ferritin genes. In conclusion, in AOSD patients, the most common MRI-finding was the presence of synovitis, characterised by intermediate to high signal intensity on T2-fat-saturated weighted and STIR images. MRI-bone erosions and bone oedema were also observed. In AOSD synovial tissues, IL-1, IL-6, and TNF pathways together with ferritin genes resulted to be hyper-expressed.

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