Detectability of Hypervascular Hepatocellular Carcinoma by Arterial Phase Images of MR and Spiral CT

1995 ◽  
Vol 36 (4-6) ◽  
pp. 372-376 ◽  
Author(s):  
Takamichi Murakami ◽  
Tonsok Kim ◽  
Hiromichi Oi ◽  
Hironobu Nakamura ◽  
Hideji Igarashi ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Spiral Ct ◽  
Arterial Phase ◽  
Breath Hold ◽  
Mr Images ◽  
Iodized Oil ◽  
Hepatocellular Carcinomas ◽  
Significant Difference ◽  
Phase Images ◽  
Arterial Chemoembolization

The ability of arterial phase images of breath-hold MR imaging and spiral CT to detect hypervascular hepatocellular carcinomas (HCCs) was evaluated. Prior to transcatheter arterial chemoembolization (TACE) with iodized oil, MR images and spiral CT during i.v. bolus injection of contrast medium (IV-MR imaging and IV-spiral CT) and spiral CT during intraarterial injection of contrast media through catheter (IA-spiral CT) of the entire liver were obtained in 24 consecutive patients with 93 HCCs. In the detection of HCCs less than 1 cm in diameter, IA-spiral CT (87.3%) was superior to IV-MR imaging (63.5%) and IV-spiral CT (54.0%) (p<0.001). There was no significant difference in detectability in any tumor size between IV-MR imaging and IV-spiral CT. IA-spiral CT was the best for detecting hypervascular HCCs, and there was no significant difference between IV-MR imaging and IV-spiral CT.

Improved Detection of Recurrent Hepatocellular Carcinomas in Arterial Phase With CAIPIRINHA-Dixon-TWIST-Volumetric Interpolated Breath-Hold Examination

2016 ◽  
Vol 51 (10) ◽  
pp. 602-608 ◽  
Author(s):  
Jinrong Qu ◽  
Shuai Han ◽  
Hongkai Zhang ◽  
Hui Liu ◽  
Zhaoqi Wang ◽  
...  
Keyword(s):  
Arterial Phase ◽  
Breath Hold ◽  
Hepatocellular Carcinomas

Detection of hepatic tumors: arterial-phase MR imaging versus spiral CT arteriography

1998 ◽  
Vol 23 (4) ◽  
pp. 416-421 ◽  
Author(s):  
M. Kanematsu ◽  
H. Hoshi ◽  
Y. Sone ◽  
R. Mochizuki ◽  
M. Kato ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Spiral Ct ◽  
Arterial Phase ◽  
Hepatic Tumors

Usefulness of composite methionine–positron emission tomography/3.0-tesla magnetic resonance imaging to detect the localization and extent of early-stage Cushing adenoma

2010 ◽  
Vol 112 (4) ◽  
pp. 750-755 ◽  
Author(s):  
Hidetoshi Ikeda ◽  
Takehiko Abe ◽  
Kazuo Watanabe
Keyword(s):  
Mr Imaging ◽  
Diagnostic Accuracy ◽  
Fdg Pet ◽  
Early Stage ◽  
False Negative ◽  
Mr Images ◽  
Cushing Disease ◽  
Significant Difference ◽  
3.0 T ◽  
Met Pet

Object Fifty to eighty percent of Cushing disease is diagnosed by typical endocrine responses. Recently, the number of diagnoses of Cushing disease without typical Cushing syndrome has been increasing; therefore, improving ways to determine the localization of the adenoma and making an early diagnosis is important. This study was undertaken to determine the present diagnostic accuracy for Cushing microadenoma and to compare the differences in diagnostic accuracy between MR imaging and PET/MR imaging. Methods During the past 3 years the authors analyzed the diagnostic accuracy in a series of 35 patients with Cushing adenoma that was verified by surgical pituitary exploration. All 35 cases of Cushing disease, including 20 cases of “overt” and 15 cases of “preclinical” Cushing disease, were studied. Superconductive MR images (1.5 or 3.0 T) and composite images from FDG-PET or methionine (MET)–PET and 3.0-T MR imaging were compared with the localization of adenomas verified by surgery. Results The diagnostic accuracy of superconductive MR imaging for detecting the localization of Cushing microadenoma was only 40%. The causes of unsatisfactory results for superconductive MR imaging were false-negative results (10 cases), false-positive results (6 cases), and instances of double pituitary adenomas (3 cases). In contrast, the accuracy of microadenoma localization using MET-PET/3.0-T MR imaging was 100% and that of FDG-PET/3.0-T MR imaging was 73%. Moreover, the adenoma location was better delineated on MET-PET/MR images than on FDG-PET/MR images. There was no significant difference in maximum standard uptake value of adenomas evaluated by MET-PET between preclinical Cushing disease and overt Cushing disease. Conclusions Composite MET-PET/3.0-T MR imaging is useful for the improvement of the delineation of Cushing microadenoma and offers high-quality detectability for early-stage Cushing adenoma.

scholarly journals Transcatheter Hepatic Subsegmental Arterial Chemoembolization Therapy Using Iodized Oil for Small Hepatocellular Carcinomas

1994 ◽  
Vol 35 (6) ◽  
pp. 576-580 ◽  
Author(s):  
R. Murakami ◽  
S. Yoshimatsu ◽  
Y. Yamashita ◽  
K. Sagara ◽  
A. Arakawa ◽  
...  
Keyword(s):  
Iodized Oil ◽  
Hepatocellular Carcinomas ◽  
Arterial Chemoembolization

Detection of Viable Tumor Cells in Hepatocellular Carcinoma following Transcatheter Arterial Chemoembolization with Iodized Oil

1993 ◽  
Vol 34 (4) ◽  
pp. 399-403 ◽  
Author(s):  
T. Murakami ◽  
H. Nakamura ◽  
S. Hori ◽  
K. Tomoda ◽  
T. Mitani ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Mr Imaging ◽  
Early Phase ◽  
Transcatheter Arterial Chemoembolization ◽  
Late Phase ◽  
Gadopentetate Dimeglumine ◽  
Liver Parenchyma ◽  
Iodized Oil ◽  
Delayed Phase ◽  
Arterial Chemoembolization

To evaluate the effect of transcatheter arterial chemoembolization (TACE) with iodized oil for hepatocellular carcinoma (HCC), dynamic turbo-fast low angle shot (turbo-FLASH) (TR/TE/flip angle/TI, 8.5/4.6/10/200) MR imaging with gadopentetate dimeglumine was performed in 10 patients with HCC after TACE with iodized oil and before partial hepatectomy. Immediately after 0.05 mmol/kg b.w. of gadopentetate dimeglumine was administered intravenously, 10 images were obtained in the first 20 s (early phase). Then, one image every 30 s from 1 to 3 min (late phase), and images at 5 min and 7 min (delayed phase) were obtained serially. In the early phase, HCC showed no enhancement in 5 patients, partial hyperintense enhancement in 4, and total hyperintense enhancement in one. Viable regions of the tumor, evaluated at histopathology, showed hyperintense enhancement relative to the surrounding liver parenchyma in the early phase, while necrotic regions showed no enhancement. Both viable and necrotic regions showed lower signal intensities than the surrounding liver parenchyma in both late and delayed phases. By using dynamic turbo-FLASH MR imaging, we were able to accurately evaluate the effect of TACE with iodized oil for HCC in 8 of the 10 patients. In 2 patients, in whom small viable cells were seen in the HCC, viable regions could not be detected with our technique. It is concluded that turbo-FLASH dynamic MR imaging was useful for evaluating the effect of TACE for HCC.

3DFT-Flash MR Imaging of Pancreatic Cancer with Gadopentetate Dimeglumine

1996 ◽  
Vol 37 (1P1) ◽  
pp. 190-194 ◽  
Author(s):  
T. Murakami ◽  
K. Tsuda ◽  
H. Nakamura ◽  
K. Osuga ◽  
K. Tomoda ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Mr Imaging ◽  
Spin Echo ◽  
Gadopentetate Dimeglumine ◽  
Pancreatic Tumors ◽  
Breath Hold ◽  
Surgical Removal ◽  
Slice Thickness ◽  
Mr Images ◽  
3 Dimensional

Purpose: We evaluated the usefulness of dynamic 3-dimensional Fourier transformation (3DFT) fast low angle shot (FLASH) MR imaging using gadopentetate dimeglumine (Gd-DTPA) to assess the extent of pancreatic cancer. Material and Methods: Breath-hold 3DFT-FLASH MR images (20/4; 25° flip angle; 7 partitions; 3–5-mm slice thickness) were obtained before the administration of 0.1 mmol/kg of Gd-DTPA, just after (early phase), and 1 and 2 min (late phases) after in 14 patients with pancreatic cancer. All patients underwent surgical removal or laparotomy. We compared the findings of T1-, T2-, and postcontrast T1-weighted spin-echo (conventional SE) and 3DFT-FLASH imaging with histologic or surgical findings. Results: Dynamic MR images could delineate the pancreatic tumors more clearly than the conventional SE images, and were useful for diagnosing vessel invasion. The contrast-to-noise ratio between the pancreatic cancer and the surrounding pancreatic parenchyma was significantly higher with the dynamic 3DFT-FLASH image than with the conventional SE images (p<0.01). Conclusion: Dynamic 3DFT-FLASH MR imaging with Gd-DTPA is useful in delineating and evaluating the extent of pancreatic cancer.

scholarly journals Prediction of Pancreatic Neuroendocrine Tumor Grading Risk Based on Quantitative Radiomic Analysis of MR

2021 ◽  
Vol 11 ◽  
Author(s):  
Wei Li ◽  
Chao Xu ◽  
Zhaoxiang Ye
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Multiple Logistic Regression Analysis ◽  
Pancreatic Neuroendocrine Tumor ◽  
Maximum Intensity ◽  
Arterial Phase ◽  
Low Grade ◽  
Mr Images ◽  
Significant Difference

BackgroundPancreatic neuroendocrine tumors (PNETs) grade is very important for treatment strategy of PNETs. The present study aimed to find the quantitative radiomic features for predicting grades of PNETs in MR images.Materials and MethodsTotally 48 patients but 51 lesions with a pathological tumor grade were subdivided into low grade (G1) group and intermediate grade (G2) group. The ROI was manually segmented slice by slice in 3D-T1 weighted sequence with and without enhancement. Statistical differences of radiomic features between G1 and G2 groups were analyzed using the independent sample t-test. Logistic regression analysis was conducted to find better predictors in distinguishing G1 and G2 groups. Finally, receiver operating characteristic (ROC) was constructed to assess diagnostic performance of each model.ResultsNo significant difference between G1 and G2 groups (P &gt; 0.05) in non-enhanced 3D-T1 images was found. Significant differences in the arterial phase analysis between the G1 and the G2 groups appeared as follows: the maximum intensity feature (P = 0.021); the range feature (P = 0.039). Multiple logistic regression analysis based on univariable model showed the maximum intensity feature (P=0.023, OR = 0.621, 95% CI: 0.433–0.858) was an independent predictor of G1 compared with G2 group, and the area under the curve (AUC) was 0.695.ConclusionsThe maximum intensity feature of radiomic features in MR images can help to predict PNETs grade risk.

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