3DFT-Flash MR Imaging of Pancreatic Cancer with Gadopentetate Dimeglumine

1996 ◽  
Vol 37 (1P1) ◽  
pp. 190-194 ◽  
Author(s):  
T. Murakami ◽  
K. Tsuda ◽  
H. Nakamura ◽  
K. Osuga ◽  
K. Tomoda ◽  
...  

Purpose: We evaluated the usefulness of dynamic 3-dimensional Fourier transformation (3DFT) fast low angle shot (FLASH) MR imaging using gadopentetate dimeglumine (Gd-DTPA) to assess the extent of pancreatic cancer. Material and Methods: Breath-hold 3DFT-FLASH MR images (20/4; 25° flip angle; 7 partitions; 3–5-mm slice thickness) were obtained before the administration of 0.1 mmol/kg of Gd-DTPA, just after (early phase), and 1 and 2 min (late phases) after in 14 patients with pancreatic cancer. All patients underwent surgical removal or laparotomy. We compared the findings of T1-, T2-, and postcontrast T1-weighted spin-echo (conventional SE) and 3DFT-FLASH imaging with histologic or surgical findings. Results: Dynamic MR images could delineate the pancreatic tumors more clearly than the conventional SE images, and were useful for diagnosing vessel invasion. The contrast-to-noise ratio between the pancreatic cancer and the surrounding pancreatic parenchyma was significantly higher with the dynamic 3DFT-FLASH image than with the conventional SE images (p<0.01). Conclusion: Dynamic 3DFT-FLASH MR imaging with Gd-DTPA is useful in delineating and evaluating the extent of pancreatic cancer.

2010 ◽  
Vol 95 (9) ◽  
pp. 4192-4196 ◽  
Author(s):  
Russell R. Lonser ◽  
Bogdan A. Kindzelski ◽  
Gautam U. Mehta ◽  
John A. Jane ◽  
Edward H. Oldfield

Context: GH-secreting pituitary adenomas are nearly always visible on conventional magnetic resonance (MR) imaging. However, management and outcome of acromegalic patients lacking imaging evidence of GH-secreting pituitary adenomas are undefined. Objective: The aim was to evaluate surgical exploration for MR-invisible GH-secreting pituitary adenomas. Design and Setting: We conducted a retrospective review at two tertiary care centers. Patients or Other Participants: Consecutive acromegalic patients without imaging evidence of a pituitary adenoma on pre- and postcontrast, spin echo T1-weighted MR imaging and who lacked evidence of an ectopic (nonpituitary) source causing GH excess were included. Interventions: Surgical exploration with identification and resection of a pituitary adenoma was performed. Main Outcome Measures: Laboratory values (GH, IGF-I), surgical findings, and clinical outcome were analyzed. Results: Six patients (three males, three females; 3% of all patients) with suspected GH-secreting adenomas did not demonstrate imaging evidence of pituitary adenoma on conventional MR imaging. Three patients underwent a postcontrast, volumetric interpolated breath-hold examination MR-imaging sequence (1.2-mm slice thickness), which revealed a 4-mm pituitary adenoma not seen on the spin echo T1-weighted MR imaging in one patient. A pituitary adenoma was identified and removed in all patients (mean diameter, 5.6 mm; range, 5 to 6.7 mm). Histological analysis confirmed that the lesions were GH-secreting adenomas. All patients achieved biochemical remission after surgical resection. Conclusion: Acromegaly can be caused by GH-secreting pituitary adenomas that are not evident on conventional MR imaging. Adenomas in some of these patients become evident using volumetric interpolated breath-hold examination MR imaging. Surgical exploration of the pituitary gland in acromegalic patients with endocrine findings consistent with a GH-secreting adenoma but negative MR imaging can lead to identification and removal of an adenoma.


2016 ◽  
Vol 67 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Michail E. Klontzas ◽  
Thomas G. Maris ◽  
Aristeidis H. Zibis ◽  
Apostolos H. Karantanas

Purpose The anatomy of the lateral knee compartment has been recently further explored with description of the anterolateral knee ligament (ALL). The purpose of this study was to confirm the presence of ALL on cadaveric knees and to describe its normal anatomy in young healthy volunteers, utilizing a high-resolution 3-dimensional (3D) pulse sequence. Methods Dissection was performed on 9 cadaveric knees in order to confirm the presence of ALL. Conventional 2-dimensional sequences of 10 knees at 1.5 T and 10 knees at 3 T, with a slice thickness of 2-4 mm, were reviewed for the presence of ALL. A 3D T2/T1-weighted gradient echo sequence (constructive interference in steady state [CISS]), yielding in-plane resolution of 0.4 mm × 0.4 mm × 0.4 mm, was applied in 14 healthy volunteers (26 knees). All 3D images were manipulated using multiplanar reconstruction (MPR) and the presence and width of ALL were recorded. Results Cadaveric dissection disclosed the presence of ALL in 8 of 9 knees. Conventional knee MR imaging depicted ALL only on coronal images (18 of 20) whereas the CISS revealed ALL on 24 of 26 studied knees (92.3%). ALL has a mean thickness of 1.1 ± 0.27 mm measured on coronal MR images. Conclusions ALL can be thoroughly assessed in young healthy individuals with the use of high-resolution 3D MR imaging with MPR at 1.5 T.


1996 ◽  
Vol 37 (2) ◽  
pp. 190-194 ◽  
Author(s):  
T. Murakami ◽  
K. Tsuda ◽  
H. Nakamura ◽  
K. Osuga ◽  
K. Tomoda ◽  
...  

Radiology ◽  
1995 ◽  
Vol 194 (2) ◽  
pp. 431-437 ◽  
Author(s):  
J N Rydberg ◽  
D J Lomas ◽  
K J Coakley ◽  
D M Hough ◽  
R L Ehman ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yasuko Tatewaki ◽  
Tatsushi Mutoh ◽  
Kazuko Omodaka ◽  
Benjamin Thyreau ◽  
Izumi Matsudaira ◽  
...  

Abstract Elongated axial length of the eye increases the morbidity of glaucoma. Myopia also associates with elongated axial length, and such ellipsoid shape of the eyeball strongly contributes its pathogenesis. Morphological features of the eyeballs, which could be important factors for developing glaucoma, have not been well described. The aim of this study was to investigate the three-dimensional (3D) topographic features of glaucomatous eyeballs with/without myopia to evaluate the potential of those features for predicting glaucoma. Using a 3.0-tesla MRI, volume-isotropic turbo-spin-echo acquisition T2-weighted images were obtained from 55 patients with glaucoma and 22 controls to delineate the eyeballs. Eyeball volumes, axial lengths and transverse lengths were semi-automatically calculated and compared between four groups: normal, myopia, glaucoma, and glaucoma with myopia. Both glaucoma and myopia increased the eyeball volume compared to the normal eyes. An increased anisotropy ratio (axial/transversus length) was observed in myopic eyes compared to normal, whereas in the glaucomatous eyes, with or without myopia, no increase in anisotropy ratio was observed. Increasing volume of eyes can be caused by myopia and glaucoma. Myopic eyes were ellipsoid in shape, but there was less anisotropy and a near-spherical shape in glaucomatous eyes, even in glaucomatous myopic eyes.


1998 ◽  
Vol 39 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Y. Kawahara ◽  
M. Uetani ◽  
N. Nakahara ◽  
Y. Doiguchi ◽  
M. Nishiguchi ◽  
...  

Purpose: the objective was to assess the efficacy of fast spin-echo (FSE) imaging in the detection of articular cartilage abnormality in osteoarthrosis of the knee Material and Methods: We studied 356 articular surfaces in 73 knees that had been examined by both MR imaging and arthroscopy. the MR images were obtained with FSE imaging (TR/TE 4200/100) on a 0.5 T unit. the surface abnormalities of the articular cartilage that were detected by MR imaging were compared with the arthroscopic findings Results: the overall sensitivity and specificity of MR in detecting chondral abnormalities were 60.5% (158/261) and 93.7% (89/95) respectively. MR imaging was more sensitive to the higher grade lesions: 31.8% (34/107) in grade 1; 72.4% (71/98) in grade 2; 93.5% (43/46) in grade 3; and 100% (10/10) in grade 4. the MR and arthroscopic grades were the same in 46.9% (167/356), and differed by no more than 1 grade in 90.2% (321/356) and 2 grades in 99.2% (353/356). the correlation between arthroscopic and MR grading scores was highly significant with a correlation coefficient of 0.705 ( p<0.0001) Conclusion: FSE sequence was less sensitive to mild cartilage abnormality but useful in detecting moderate to severe abnormality and in evaluating the degree of articular cartilage abnormality


1998 ◽  
Vol 170 (1) ◽  
pp. 127-128 ◽  
Author(s):  
O Ernst ◽  
T Asselah ◽  
X Cablan ◽  
G Sergent

1993 ◽  
Vol 34 (6) ◽  
pp. 625-630
Author(s):  
Y. Noguchi ◽  
S. Takashima ◽  
J. Ikezoe ◽  
M. Yoshii ◽  
T. Koide ◽  
...  

MR images of the neck were prospectively studied in 19 patients with hyperparathyroidism. Fast low angle shot (FLASH) sequence was performed in addition to T1- and T2-weighted spin echo (SE) sequences. FLASH images were obtained with 320/12/20° (TR/TE/flip angle) using presaturation technique. TE of 12 ms was chosen to eliminate high signal of fat tissue. In the evaluation of detectability, a combination of T1-weighted SE and FLASH images (T1WI + FLASH) was compared with a combination of T1- and T2-weighted SE images (T1WI + T2WI). MR imaging correctly depicted 20 of 30 abnormal glands on both T1WI + FLASH and T1WI + T2WI. FLASH imaging effectively eliminated high signal of fat tissue. Nineteen abnormal glands demonstrated higher signal than surrounding tissues on FLASH images, whereas 12 glands were high-intense on T2-weighted SE images. We conclude that FLASH imaging provides improved tissue contrast and anatomic delineation and, thus, may replace T2-weighted SE imaging in the neck.


2010 ◽  
Vol 113 (1) ◽  
pp. 74-78 ◽  
Author(s):  
Ahmed K. Toma ◽  
Andrew Tarnaris ◽  
Joan P. Grieve ◽  
Laurence D. Watkins ◽  
Neil D. Kitchen

Object In this paper, the authors' goal was to compare the artifact induced by implanted (in vivo) adjustable shunt valves in spin echo, diffusion weighted (DW), and gradient echo MR imaging pulse sequences. Methods The MR images obtained in 8 patients with proGAV and 6 patients with Strata II adjustable shunt valves were assessed for artifact areas in different planes as well as the total volume for different pulse sequences. Results Artifacts induced by the Strata II valve were significantly larger than those induced by proGAV valve in spin echo MR imaging pulse sequence (29,761 vs 2450 mm3 on T2-weighted fast spin echo, p = 0.003) and DW images (100,138 vs 38,955 mm3, p = 0.025). Artifacts were more marked on DW MR images than on spin echo pulse sequencse for both valve types. Conclusions Adjustable valve–induced artifacts can conceal brain pathology on MR images. This should influence the choice of valve implantation site and the type of valve used. The effect of artifacts on DW images should be highlighted pending the development of less MR imaging artifact–inducing adjustable shunt valves.


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