scholarly journals Optimal dilution of contrast medium for quantitating parenchymal blood volume using a flat-panel detector

2017 ◽  
Vol 46 (1) ◽  
pp. 464-474 ◽  
Author(s):  
Takumi Kuriyama ◽  
Nobuyuki Sakai ◽  
Mikiya Beppu ◽  
Chiaki Sakai ◽  
Hirotoshi Imamura ◽  
...  

Objective Similar to perfusion studies after acute ischemic stroke, measuring cerebral blood volume (CBV) via C-arm computed tomography before and after therapeutic interventions may help gauge subsequent revascularization. We tested serial dilutions of intra-arterial injectable contrast medium (CM) to determine the optimal CM concentration for quantifying parenchymal blood volume by flat-panel detector imaging (FD-PBV). Methods CM was diluted via saline power injector, instituting time delays for FD-PBV studies. A red/green/blue (RGB) color scale was employed to quantify/compare FD-PBV and magnetic resonance-derived CBV (MRCBV). Results Contrast values of right and left common carotid arteries did not differ significantly at CM dilutions of ≥20%. RGB analysis of FD-PBV imaging (relative to MR-CVB), showed CM dilution altered the colors (by 16%), increasing red and decreasing blue ratios. Conclusion Diluting CM to 20% resulted in no laterality differential of FD-PBV imaging, with left/right quantitative ratios approaching 1.1 (optimal for clinical use).

2012 ◽  
Vol 18 (4) ◽  
pp. 463-468 ◽  
Author(s):  
C-J. Lin ◽  
M. Yu ◽  
S-C. Hung ◽  
M.M.H. Teng ◽  
W-Y. Guo ◽  
...  

In acute ischemic stroke, the ability to estimate the penumbra and infarction core ratio helps to triage those who will potentially benefit from thrombolytic therapies. Flat-panel post-contrast DynaCT imaging can provide both vasculature and parenchymal blood volume within the angio room to monitor hemodynamic changes during the endovascular procedures. We report on an 80-year-old woman who suffered from an acute occlusion of the right distal cervical internal carotid artery. She was transferred to the angio room where in-room post-contrast flat-panel DynaCT imaging (syngo Neuro PBV IR) was performed to access the ischemic tissue, followed by successful mechanical thrombolytic therapy.


2005 ◽  
Vol 46 (6) ◽  
pp. 657-661 ◽  
Author(s):  
B. Sjöholm ◽  
H. Geijer ◽  
J. Persliden

Purpose: To compare radiation doses given to patients undergoing IVU (intravenous urography) before and after digitalization of our X-ray department. Material and Methods: IVU examinations were monitored with dose area product meters before and after the X-ray department changed to digital techniques. The first step was a change from film-screen to storage phosphor plates, while the second step involved changing to a flat panel detector. Forty-two patients were included for the film-screen situation, 69 when using the storage phosphor plates, and 70 using the flat panel detector. Results: A dose reduction from 41.8 Gycm2 to 31.5 Gycm2 was achieved with the first step when the film-screen system was replaced with storage phosphor plates. A further reduction to 12.1 Gycm2 was achieved using the flat panel detector. Conclusion: The introduction of the flat panel detectors made a considerable dose reduction possible.


Stroke ◽  
2019 ◽  
Vol 50 (11) ◽  
pp. 3274-3276 ◽  
Author(s):  
Aneka Mueller ◽  
Marlies Wagner ◽  
Elke Hattingen ◽  
Alexander Seiler ◽  
Se-Jong You ◽  
...  

Background and Purpose— Patients with large-vessel stroke frequently need to be transferred to comprehensive stroke centers for endovascular treatment. An update of physiological perfusion parameters and stroke progression on arrival is desirable. We examined the reliability of preinterventional pooled blood volume (PBV)-maps acquired by flat-panel detector computed tomography (CT) in the interventional angiography suite. Methods— The volumes of preinterventional perfusion deficit in flat-panel detector CT-PBV source images were compared with final infarct volume on follow-up multislice-CT after endovascular treatment of 29 consecutive patients with occlusion of the middle cerebral artery (MCA) or the distal internal carotid artery (ICA). Results— Endovascular treatment was successful in 26 patients (Thrombolysis in Cerebral Infarction, 2b-3). Overall, the median preinterventional PBV-deficit was 9×larger than median final infarct volume on multislice-CT (86.4 mL [10.3; 111.6] versus 9.6 mL [3.6; 36.8]). This was especially evident in the subgroup of successful recanalization (PBV-deficit: 87.5 mL [10.6; 115.1], final infarct: 8.7 mL [3.6; 29]). In futile recanalization, the final infarct tended to be underestimated (PBV-deficit: 86.4 mL [5.9; –] and final infarct: 116.4 mL [3.5; –]). Conclusions— Flat panel detector CT-PBV is not reliable in predicting the final infarct volume and should not be used in clinical decision making for endovascular treatment of acute cerebral artery occlusions.


2013 ◽  
Vol 7 (3) ◽  
pp. 145-155 ◽  
Author(s):  
Hiroshi ITOKAWA ◽  
Masao MORIYA ◽  
Michio FUJIMOTO ◽  
Yoshiyuki TOMITA ◽  
Noriyoshi OKAMOTO ◽  
...  

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