Fallopian tube serous adenocarcinoma with dizziness as the initial symptom: a case report

Paroxysmal vertigo as the presenting symptom of a fallopian tube tumor is rare among patients. We present a patient who was finally diagnosed with fallopian tube serous adenocarcinoma with subacute cerebellar degeneration. We analyzed the patients’ clinical, pathological, and imaging data. We conclude that the possibility of paraneoplastic neurological syndrome should be considered when conventional treatment is ineffective for a fallopian tube tumor and other neurological diseases are excluded.

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Spinal Metastases from a Primary Fallopian Tube Serous Adenocarcinoma: A Case Report

Global Spine Journal ◽

10.1055/s-0035-1546417 ◽

2015 ◽

Vol 5 (5) ◽

pp. 65-68 ◽

Cited By ~ 4

Author(s):

Jonathan P. Eskander ◽

Eren O. Kuris ◽

Andrew J. Younghein ◽

Samuel Landsman ◽

Leonard Japko ◽

...

Keyword(s):

Case Report ◽

Fallopian Tube ◽

Spinal Metastases ◽

Serous Adenocarcinoma

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Paraneoplastic Neurological Syndrome in Fallopian Tube Cancer

Geburtshilfe und Frauenheilkunde ◽

10.1055/s-0034-1383041 ◽

2014 ◽

Vol 74 (10) ◽

pp. 950-953 ◽

Cited By ~ 2

Author(s):

E. Maas ◽

T. Skoberne ◽

A. Werner ◽

S. Braun ◽

C. Jackisch

Keyword(s):

Fallopian Tube ◽

Paraneoplastic Neurological Syndrome ◽

Fallopian Tube Cancer ◽

Neurological Syndrome

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Small-Cell Carcinoma of the Esophagus Associated with a Paraneoplastic Neurological Syndrome: A Case Report Documenting a Complete Response

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyi241 ◽

2006 ◽

Vol 36 (2) ◽

pp. 109-112 ◽

Cited By ~ 9

Author(s):

Takuya Shimoda ◽

Wasaburou Koizumi ◽

Satoshi Tanabe ◽

Katuhiko Higuchi ◽

Tohru Sasaki ◽

...

Keyword(s):

Case Report ◽

Cell Carcinoma ◽

Small Cell Carcinoma ◽

Complete Response ◽

Paraneoplastic Neurological Syndrome ◽

Small Cell ◽

Carcinoma Of The Esophagus ◽

Neurological Syndrome

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Paraneoplastic cerebellar degeneration heralding recurrence of fallopian tube adenocarcinoma: A case report and literature review

Gynecologic Oncology Reports ◽

10.1016/j.gore.2020.100624 ◽

2020 ◽

Vol 33 ◽

pp. 100624

Author(s):

Abigail Cain ◽

Lindsey Buckingham ◽

Allison Staley ◽

Leslie H. Clark

Keyword(s):

Case Report ◽

Literature Review ◽

Fallopian Tube ◽

Cerebellar Degeneration ◽

Paraneoplastic Cerebellar Degeneration

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Anti-Ri-associated paraneoplastic neurological syndrome: Initial symptom of breast cancer with HER2 overexpression and treatment by dual HER2 blockade

Journal of Oncology Pharmacy Practice ◽

10.1177/1078155218792672 ◽

2018 ◽

Vol 25 (6) ◽

pp. 1526-1530 ◽

Cited By ~ 1

Author(s):

Omer Fatih Olmez ◽

Oguzcan Kinikoglu ◽

Nesrin Helvacı Yilmaz ◽

Ahmet Bilici ◽

Erdem Cubukcu ◽

...

Keyword(s):

Breast Cancer ◽

Female Patient ◽

Paraneoplastic Neurological Syndrome ◽

Her2 Overexpression ◽

Initial Symptom ◽

Her2 Positive ◽

Neurological Syndrome ◽

Her2 Positive Breast Cancer ◽

First Case ◽

Positive Breast Cancer

Paraneoplastic neurological syndrome is associated with anti-Ri antibodies, which are typically present with opsoclonus–myoclonus–ataxia. Human epidermal growth factor receptor 2 (HER2) overexpression is present in 15%–25% of breast cancer and is associated with poor prognosis. There are a few reports of paraneoplastic neurological syndrome associated with HER2-positive breast cancer in the literature, of which most are anti-Yo-associated paraneoplastic neurological syndrome. We present herein the case of a female patient with HER2-positive breast cancer who had atypical anti-Ri antibody associated with opsoclonus–myoclonus paraneoplastic neurological syndrome. Following the diagnosis of paraneoplastic syndrome, chemotherapy with dual HER2 blockade and immunomodulating treatment including intravenous immunoglobulin and oral prednisolone were administered. Although the patient was negative for serum anti-Ri antibodies, there was partial clinical improvement and her neurological deficit persisted. To our knowledge, this is the first case report of female patient with HER2-positive breast cancer who had atypical anti-Ri antibody associated with opsoclonus–myoclonus paraneoplastic neurological syndrome and treated with dual HER2 blockade.

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