Investigation of Bilirubin Removal by NK-110 Resin Hemoperfusion in Jaundiced Dogs

1986 ◽  
Vol 9 (5) ◽  
pp. 327-330 ◽  
Author(s):  
S. Ji-Chang ◽  
Q. Shao-Cheng ◽  
Z. Chen-Yang ◽  
N. Fu-Hua ◽  
H. Shao-Ming ◽  
...  
Keyword(s):  
Inferior Vena ◽  
Total Bilirubin ◽  
Vena Cava ◽  
Blood Gases ◽  
Adsorption Properties ◽  
Rubber Tube ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance ◽  
Flow Through

A jaundiced dog model was made by common bile duct-inferior vena cava shunt with a silicon rubber tube. Blood bilirubin levels increased from 0.25 ± 0.16 (SD) mg% to 15 ± 1.4 (SD) mg%. These dog models were treated with a column containing 200 gm of macroreticular resin NK-110 which was linked between the femoral artery and vein. The rate of blood flow through the column was 200 ml/min. It was shown that total bilirubin reduced from 15 ± 1.4 (SD) to 7.4 ± 0.61 (SD), conjugated bilirubin decreased from 6.97 ± 0.63 to 3.5 ± 0.33 (SD) and unconjugated bilirubin from 7.8 ± 2.1 to 4.2 ± 0.4 (SD). There were no significant changes in protein, electrolyte, blood gases and acid base balance. Results show that NK-110 resin has good blood-compatible and adsorption properties.

DIGITALIS TOLERANCE IN YOUNG PUPPIES

PEDIATRICS ◽  
1970 ◽  
Vol 46 (5) ◽  
pp. 730-736
Author(s):  
Katherine H. Halloran ◽  
Steven C. Schimpff ◽  
Jean G. Nicolas ◽  
Norman S. Talner
Keyword(s):  
Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Littermate Control ◽  
Premature Ventricular Contractions ◽  
Toxic Dose ◽  
Arterial Blood ◽  
Wide Range ◽  
Base Balance ◽  
The Mean

Tolerance to acetyl strophanthidin, a rapid-acting cardiac aglycone, was determined in 28 anesthetized mongrel puppies, ages 16 to 56 days, and compared to tolerance in 16 littermate puppies in whom acute hypercapnic acidemia was produced. The tolerance was also compared to that of four adult mongrel dogs. The toxic dose was defined as the intravenous amount required to produce four consecutive premature ventricular contractions. A marked variation in the toxic dose was found in the 28 control puppies (range 83 to 353 µg/kg, mean 169 µg/kg) which could not be correlated with age, arterial blood gases or pH, serum potassium or sodium, arterial pressure, or heart rate. The toxic dose was significantly greater in the puppies than in the adult dogs, in whom the mean toxic dose was 64 µg/kg (range 50 to 89 µg/kg). A significant increase in tolerance was also observed in the puppies with hypercapnic acidemia (mean toxic dose 220 µg/kg, range 93 to 375 µg/kg) in comparison to tolerance in the control puppies and despite the wide range of tolerance, each of the puppies with hypercapnic acidemia showed greater tolerance than its littermate control puppy. Assessment of the clinical implications of these findings will require study of the effects of alterations in acid-base balance on the inotropic effect of acetyl strophanthidin in addition to the toxic electrophysiologic effects.

Electrolytes, Blood Gases, and Acid–Base Balance

2017 ◽  
pp. 873-938
Author(s):  
Isabel A. Lea ◽  
Susan J. Borghoff ◽  
Gregory S. Travlos
Keyword(s):  
Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

Arterial Blood Gases, Acid-Base Balance, and Lactate and Gas Exchange Variables During Hypoxic Exercise

1989 ◽  
Vol 10 (04) ◽  
pp. 279-285 ◽  
Author(s):  
T. Yoshida ◽  
M. Udo ◽  
M. Chida ◽  
K. Makiguchi ◽  
M. Ichioka ◽  
...  
Keyword(s):  
Gas Exchange ◽  
Blood Gases ◽  
Arterial Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Arterial Blood ◽  
Base Balance ◽  
Hypoxic Exercise

Effect of a scorpion (Leiurus quinquestriatus H and E) venom on blood gases and acid-base balance in the rat

Toxicon ◽  
1982 ◽  
Vol 20 (4) ◽  
pp. 802-805 ◽  
Author(s):  
F. Tash ◽  
Kh. Ghoneim ◽  
N. Swelam ◽  
M.F. Bassiony ◽  
M.F. El-Asmar
Keyword(s):  
Blood Gases ◽  
Acid Base Balance ◽  
Acid Base ◽  
Base Balance

Blood Gas Analysis and the Fundamentals of Acid-Base Balance

2009 ◽  
Vol 28 (2) ◽  
pp. 125-128 ◽  
Author(s):  
Mary Farmand
Keyword(s):  
Systematic Approach ◽  
Blood Gases ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Acid Base Balance ◽  
Bedside Nurse ◽  
Acid Base ◽  
Neonatal Nursing ◽  
Base Balance

UNDERSTANDING BLOOD GAS values and acid-base balance are fundamental skills of neonatal nursing. This is because, in the NICU, blood gases are probably ordered more than any other laboratory test. The bedside nurse not only obtains the specimen, but is also crucially involved in interpreting the results because blood gases cannot stand alone; they need to be evaluated in the context of the entire clinical picture. This article provides basic information on the components of a blood gas, acid-base balance, as well as a systematic approach to blood gas analysis.

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