Effect of a novel technique of posterior reconstruction of pubourethralis on ‘early’ return of continence after robot assisted radical prostatectomy (RARP): A comparative study

2021 ◽  
pp. 039156032110070
Author(s):  
Malik Abdul Rouf ◽  
Venkatesh Kumar ◽  
Anshuman Agarwal ◽  
Mahender Sharma ◽  
Suresh Kumar Rawat ◽  
...  

Objective: To study the effect of a novel technique of posterior reconstruction of pubourethralis on early return of continence after robot assisted radical prostatectomy (RARP). Materials and methods: The study included 206 patients of organ confined prostate cancer managed at our centre between March 2014 and December 2018.The patients were randomly distributed into two comparable groups with respect to age, height, weight and BMI, with 100 patients in control and 106 patients in study group. After standard excision of the specimen, the posterior reconstruction in the form of Rocco stitch was done in control group while in addition to Rocco stitch pubourethralis was approximated posteriorly in midline at the proposed site of vesicourethral anastomosis in study group. Continence was defined as the need to use 0–1 pad in 24 h. The data was collected on day 0, 3, 7, 15, 30, 90 and 180 after removal of catheter. Results: At day zero, 3,7, 15, 30, 90 and 180 days after catheter removal continence rates (⩽1 pad usage per day) were observed to be 18.8% versus 0%, 22.6% versus 0%, 50.9% versus 5%, 72.6% versus 20%, 84.9 versus 32%, 97.1% versus 83%, and 97.1% versus 91% in the study and control group respectively. Conclusion: Despite small number of patients in this study the results with respect to early return of continence are encouraging in the reconstruction group and there by in favour of this technique .Furthermore the technique is easily reproducible and may be seen as one more additional step to be applied in order to enhance the recovery of continence after RARP. However it is necessary to further validate the efficacy of this procedure through multicenteric controlled trials.

2020 ◽  
Author(s):  
Yan Zhu ◽  
Yan Guo ◽  
Juan Ma ◽  
Mao-shi Li ◽  
Jia-fei Chen ◽  
...  

Abstract Objective: To compare the epidemiological and clinical characteristics of confirmed and suspected corona virus disease 2019 (COVID-19) cases via the process of “triage-screening-isolation-transfer” in the hospitals of non-epidemic areas.Methods: The general data, epidemiological history, clinical symptoms, laboratory examination, and chest computed tomography (CT) imaging characteristics of 38 patients with suspected COVID-19, admitted between January 21 and March 5, 2020, were analyzed.Results: According to the results of the novel severe acute respiratory syndrome coronavirus (SARS-CoV-2) ribonucleic acid (RNA) testing, the patients were divided into study group (RNA positive) and control group (RNA negative). Ultimately, 8 cases were RNA-positive and diagnosed as CDVID-19, and 30 cases were negative. Approximately half of the patients in the study group returned to Chongqing from Wuhan; this number was significantly larger than that of the control group (P<0.05). The number of subjects in close contact with the confirmed cases with SARS-CoV-2 RNA-positive and the incidence of aggregation was significantly larger in the study group than in the control group (both P<0.05). The clinical symptom of the study group was mainly low fever (with or without cough). The patients with decreased white blood cells (WBC) in the study group were significantly more than those in the control group (P<0.05). Both group had reduced lymphocytes (Lym) but the number of patients with increased C-reactive protein (CRP) in the study group was significantly more than that in the control group (P<0.05). There were different degrees of chest CT abnormalities in both study and control group (P > 0.05). Conclusion: The epidemiological investigations in screening for infectious diseases is crucial. The risk of infection was high from the primary epidemic area and/or in close contact with the confirmed case. The most common form of clustering occurrence was family aggregation. CDVID-19 was mainly characterized by fever and respiratory symptoms, although asymptomatic infection may also occur. Decreased WBC, decreased Lym, and increased CRP are common characteristics but can also be combined with other respiratory tract virus infections. COVID 19 screening by chest CT alone had certain limitations in non- epidemic areas.


2013 ◽  
Vol 5 (3) ◽  
pp. 188
Author(s):  
Kevin C. Zorn ◽  
Hugues Widmer ◽  
Jean-Baptiste Lattouf ◽  
Dan Liberman ◽  
Naeem Bhojani ◽  
...  

Purpose: Our purpose was to describe the safety and feasibility ofa running posterior reconstruction (PR) integrated with continuousvesicourethral anastomosis (VUA) using a novel self-cinchingunidirectional barbed suture in robot-assisted radical prostatectomy(RARP).Methods: Between March and October 2010, 30 consecutivepatients with organ-confined prostate cancer underwent RARP byan experienced single surgeon (KCZ). Upon completion of radicalprostatectomy, urinary reconstruction was carried out using2 knotless, interlocked 6-inches 3-0 V-Loc-180 suture. The lefttail of the suture was initially used for PR (starting at 5-o’clockand ran to re-approximate the retrotrigonal layer to the rectourethralis)followed by left-sided VUA (from 6- to 12-o’clock), whilethe right-sided suture completed the right-sided VUA. Assuranceof watertight closure with an intraoperative 300 cc saline visualcystogram was performed in all cases prior to case completion.Perioperative outcomes and 30-day complications were recorded.Results: All anastamoses were performed without assistance andwithout knot tying. Median time for nurse setup and urinary reconstructionwas 40 seconds (interquartile range [IQR] 25-60) and14.6 min (IQR 10-18), respectively. The need to readjust suturetension or place Lapra-Ty clips (Ethicon Endo-Surgery, Cincinnati,OH) to establish watertight closure was observed in 2 cases (7%).No patient had clinical urinary leak and there was no urinary retentionafter catheter removal on mean postoperative day 5 (IQR 4-6).Conclusions: Our clinical experience with a novel technique usingthe interlocked V-Loc suture during RARP for both PR and anastomosisappears to be safe and efficient. Using the barbed sutureprevents slippage and eliminates the need for bedside assistanceto maintain suture tension or knot tying, thus assuring watertighttissue closure.Objectif : Notre but était de décrire l’innocuité et la faisabilitéd’une reconstruction postérieure (RP) intégrée à une anastomosevésico-urétrale continue à l’aide de la nouvelle technique de sutureavec fils barbelés unidirectionnels et ancrage automatique aprèsprostatectomie radicale assistée par robot (PRAR).Méthodologie : Entre mars et octobre 2010, 30 patients consécutifsatteints d’un cancer de la prostate confiné à la glande ont subi unePRAR effectuée par un chirurgien expérimenté (KCZ). Après laprostatectomie radicale, une reconstruction urinaire a été entrepriseà l’aide de 2 sutures 3-0 de 6 pouces sans noeud par le dispositifV-Loc 180. L’extension gauche de la suture a d’abord été utiliséepour la PR (en commençant à 5 heures et en poursuivant pourrapprocher la couche rétrotrigonale du muscle recto-urétral) etsuivie d’une anatostomose vésico-urétrale du côté gauche (de 6 à12 heures), alors que la partie droite de la suture a permis de terminerl’anastomose vésico-urétrale droite. Une fermeture hermétiquepar cystogramme visuel intraopératoire avec 300 mL de solutionsalée dans tous les cas a été réalisée avant la fin de l’intervention.Les résultats peropératoires et les complications émergeant pendantles 30 jours suivants ont été consignés.Résultats : Toutes les anastomoses ont été effectuées sans aide etsans noeud. Le temps médian pour la préparation par l’infirmièreet la reconstruction urinaire était de 40 secondes (écart interquartile[EIQ] 25-60) et de 14,6 minutes (EIQ 10-18), respectivement.Dans 2 cas (7%), on a eu besoin de rajuster la tension des pointsde suture ou de placer des agrafes LapraTy (Ethicon Endo-Surgery,Cincinnati, OH) pour assurer une fermeture hermétique. Aucunpatient n’a présenté de fuite urinaire clinique ni aucune rétentionurinaire après le retrait du cathéter en moyenne 5 jours aprèsl’opération (EIQ 4-6).Conclusions : Selon notre expérience clinique, cette nouvelle techniquede fermeture de plaie par le dispositif V-Loc pour une PRARavec anastomose semble sans danger et efficace. L’usage des fils barbelés empêche le glissement et élimine le besoin d’aide afind’assurer la bonne tension des points de suture ou de noeuds, etassure une fermeture hermétique des tissus.


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