Relationship Between Dysfunctional Cognitions and Depressive Subtypes

1987 ◽  
Vol 32 (3) ◽  
pp. 194-198 ◽  
Author(s):  
William H. Norman ◽  
Ivan W. Miller ◽  
Gabor I. Keitner
Keyword(s):  
Attitude Scale ◽  
Dexamethasone Suppression Test ◽  
Dysfunctional Cognitions ◽  
Dysfunctional Attitude ◽  
Suppression Test ◽  
Severity Of Depression ◽  
Dysfunctional Attitude Scale ◽  
Depressive Subtypes ◽  
The Relationship ◽  
Dexamethasone Suppression

The results of this study suggest that the relationship between cognitions and severity of depression hypothesized by cognitive theorists may be relevant only to a subgroup of depressives. In a sample of 40 inpatients with major depression who received the Dexamethasone Suppression Test (DST), scores on the Dysfunctional Attitude Scale were equivalent in suppressor and nonsuppressor groups, as well as in melancholic and nonmelancholic depressive groups. Neither was there a difference between suppressors and nonsuppressor s on measures of depression. However, in the nonmelancholic group, there was a significant relationship between dysfunctional cognitions and severity of depression. This relationship was not found in the melancholic group. Finally, independent of diagnostic and biological subtype, patients with elevated levels of dysfunctional cognitions when compared with the remaining sample revealed greater severity of depression, more days in hospital and more readmissions to hospital.

Are depression and denutrition good predictors of dexamethasone suppression test (DST) in anorexia nervosa?

1998 ◽  
Vol 13 (8) ◽  
pp. 411-418 ◽  
Author(s):  
C Massoubre ◽  
F Lang ◽  
L Millot ◽  
M Pichon ◽  
B Estour ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Stepwise Regression ◽  
Serum Cortisol ◽  
Dexamethasone Suppression Test ◽  
Stepwise Logistic Regression ◽  
Independent Variables ◽  
Suppression Test ◽  
Depression Scales ◽  
The Relationship ◽  
Dexamethasone Suppression

SummaryThis study was conducted to investigate the corticotropic axis in anorexia nervosa. In 93 female inpatients who met DSM-III-R criteria for anorexia nervosa, subsample (n = 64) with DSM-III criteria was also considered. Using stepwise regression analysis, this study examined the relationship between independent variables ie, age, body mass index, scores on depression scales and postdexamethasone serum cortisol, considered as a dependent variable. In patients who met DSM-III criteria, 16.7% of the variance of serum cortisol can be explained. The main predictors are depressive retardation, emaciation and age. Using stepwise logistic regression the main categorical predictors of the test suppression vs non suppression are of the same nature. The condition of realisation of DST are discussed.

Binding of yohimbine and imipramine to platelets in depressive illness

1986 ◽  
Vol 16 (4) ◽  
pp. 765-773 ◽  
Author(s):  
L. Braddock ◽  
P. J. Cowen ◽  
J. M. Elliott ◽  
S. Fraser ◽  
K. Stump
Keyword(s):  
Radioligand Binding ◽  
Antidepressant Treatment ◽  
Depressive Illness ◽  
Dexamethasone Suppression Test ◽  
Binding Characteristics ◽  
Imipramine Binding ◽  
Suppression Test ◽  
Severity Of Depression ◽  
Dexamethasone Suppression

SynopsisRadioligand binding to intact platelets was carried out in antidepressant-free patients and the 1 mg dexamethasone suppression test (DST) was performed. There were no differences in binding characteristics between patients and controls for either [H]yohimbine or [H]imipramine. There were no differences in binding between patients classified as endogenous using the Newcastle Scale, compared with non-endogenous patients, and no difference between DST suppressors and non-suppressors. The severity of depression did not affect binding values. After 4–6 weeks antidepressant treatment [H]yohimbine binding was significantly reduced but [H]imipramine binding was unaffected.

An American Validation Study of the Newcastle Diagnostic Scale: I. Relationship with the Dexamethasone Suppression Test

1986 ◽  
Vol 149 (5) ◽  
pp. 627-630 ◽  
Author(s):  
M. Zimmerman ◽  
B. Pfohl ◽  
D. Stangl ◽  
W. Coryell
Keyword(s):  
Validation Study ◽  
Endogenous Depression ◽  
Dexamethasone Suppression Test ◽  
Non Linear ◽  
Hospital Patients ◽  
Suppression Test ◽  
The Relationship ◽  
Dexamethasone Suppression ◽  
Diagnostic Index

The Newcastle diagnostic index was completed on 159 depressedin-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after con trolling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.

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