scholarly journals Successful integration of HIV pre-exposure prophylaxis into a community-based HIV prevention program for female sex workers in Kolkata, India

2021 ◽  
Vol 32 (7) ◽  
pp. 638-647
Author(s):  
Smarajit Jana ◽  
Protim Ray ◽  
Soma Roy ◽  
Abhijit Kadam ◽  
Raman R Gangakhedkar ◽  
...  

We assessed the impact of pre-exposure prophylaxis (PrEP) in the context of a community-based HIV program among female sex workers (FSWs) in Kolkata, India. This was an open-label, uncontrolled demonstration trial. HIV seronegative FSWs over 18 years were eligible. Participants were administered daily tenofovir/emtricitabine (TDF-FTC) with follow-up visits at months 1, 3, 6, 9, 12, and 15. Drug adherence was monitored by self-report, and a random subset of participants underwent plasma TDF testing. 843 women were screened and 678 enrolled and started on PrEP. Seventy-nine women (11%) did not complete all scheduled visits: four women died of reasons unrelated to PrEP and 75 withdrew, for a 15-month retention rate of 89%. Self-reported daily adherence was over 70%. Among those tested for TDF, the percentage of women whose level reached ≥40 ng/mL was 65% by their final visit. There were no HIV seroconversions, and no evidence of significant changes in sexual behavior. This study demonstrated the feasibility and effectiveness of PrEP for FSWs in Kolkata, with very high levels of adherence to PrEP and no HIV seroconversions. The integration of PrEP into an existing community-based HIV prevention program ensured community support and facilitated adherence.

AIDS Care ◽  
2017 ◽  
Vol 29 (11) ◽  
pp. 1453-1457 ◽  
Author(s):  
Sarah M. Peitzmeier ◽  
Catherine Tomko ◽  
Erin Wingo ◽  
Anne Sawyer ◽  
Susan G. Sherman ◽  
...  

2011 ◽  
Vol 11 (Suppl 6) ◽  
pp. S3 ◽  
Author(s):  
S Thilakavathi ◽  
K Boopathi ◽  
CP Girish Kumar ◽  
A Santhakumar ◽  
R Senthilkumar ◽  
...  

2014 ◽  
Vol 41 (6) ◽  
pp. 380-387 ◽  
Author(s):  
Michel Alary ◽  
Pradeep Banandur ◽  
Subramanian Potty Rajaram ◽  
Usha K. Thamattoor ◽  
Mandar K. Mainkar ◽  
...  

2013 ◽  
Vol 89 (Suppl 1) ◽  
pp. A390.2-A390
Author(s):  
S Rajaram ◽  
M Alary ◽  
P Banandur ◽  
U K Thammattoor ◽  
T Thomas ◽  
...  

2019 ◽  
Author(s):  
Daniel Nyato ◽  
Soori Nnko ◽  
Albert Komba ◽  
Evodius Kuringe ◽  
Marya Plotkin ◽  
...  

AbstractBackgroundHIV-infected female sex workers (FSWs) have poor linkage to HIV care in sub-Sahara Africa.MethodsWe conducted 21 focus group discussions (FGDs) to explore factors influencing linkage to HIV care among FSWs tested for HIV through a comprehensive community-based HIV prevention project in Tanzania.ResultsInfluences on linkage to care were present at the system, societal and individual levels. System-level factors included unfriendly service delivery environment, including lengthy pre-enrolment sessions, concerns about confidentiality, stigmatising attitudes of health providers. Societal-level factors included myths and misconceptions about ART and stigma. On the individual level, most notable was fear of not being able to continue to have a livelihood if one’s status were to be known. Facilitators were noted, including the availability of transport to services, friendly health care providers and peer-support referral and networks.ConclusionFindings of this study underscore the importance of peer-supported linkages to HIV care and the need for respectful, high-quality care.


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