Clove Oil Ingestion in an Infant

1991 ◽  
Vol 10 (4) ◽  
pp. 291-294 ◽  
Author(s):  
Brian W. Lane ◽  
Matthew J. Ellenhorn ◽  
Tim V. Hulbert ◽  
Margaret McCarron

A case is presented in which a 7-month-old child developed central nervous system depression, urinary abnormalities and a large anion-gap acidosis after the accidental oral administration of clove oil. Supportive care and gastric lavage were sufficient for total recovery of the patient. Possible mechanisms of the depression and acidosis are discussed, and suggestions for treatment are presented.

2019 ◽  
Author(s):  
Bryan Cook ◽  
Krystina Geiger ◽  
Megan Barra

Opioid agonists are frequently used to provide anesthesia in combination with sedatives and hypnotic agents and manage postoperative acute pain. There are many different opioid agents available that differ in their potency, onset and duration of action, metabolism, drug interactions, and side-effect profile. All opioids have distinct effects upon various organ systems, including central nervous system depression, respiratory depression, and decreased gastrointestinal motility. Fentanyl and fentanyl-derived agents (alfentanil, sufentanil, remifentanil) are most frequently used in the intraoperative period due to their quick onset and duration of action, allowing them to be easily titrated and discontinued at the completion of a procedure. Oral opioids with moderate durations of action, such as oxycodone, hydrocodone, and morphine, are commonly used for acute pain management in the postoperative setting. When oral analgesics cannot be used, intravenous patient-controlled analgesia is another option for pain management. This review contains 5 figures, 11 tables, and 59 references. Key Words: analgesia, anesthesia, central nervous system depression, fentanyl, morphine, opioid agonist, pain management, patient-controlled analgesia, perioperative, respiratory depression


1961 ◽  
Vol 16 (2) ◽  
pp. 361-366 ◽  
Author(s):  
G. W. Granger

Following light adaptation to a luminance of 120 mL for 5 minutes, absolute thresholds for a centrally fixated, 7-degree test field in 'white' light were measured during the course of 30 minutes' dark adaptation. Viewing was monocular and the measuring light was exposed in 0.018-second flashes. The resulting curves, defining the relation between log threshold luminance and time in the dark, displayed the typical features of 'rod' dark adaptation and were found to be highly reproducible in three experienced observers. Neither the shape of the curves nor their position along the log luminance axis was affected by the oral administration of a sedative dose (0.30 gm/70 kg) of amobarbital. It was concluded that the results supported the views of Hecht and other photochemical theorists concerning the stability of human dark adaptation and its resistance to fluctuations in the state of the central nervous system, but were not necessarily incompatible, as was sometimes supposed, with the hypothesis of a neural component in visual adaptation. Submitted on May 23, 1960


2009 ◽  
Vol 71 (11) ◽  
pp. 1465-1471 ◽  
Author(s):  
Kazuto YAMASHITA ◽  
Natsuki AKASHI ◽  
Yumiko KATAYAMA ◽  
Yosuke UCHIDA ◽  
Mohammed A. UMAR ◽  
...  

1984 ◽  
Vol 2 (3) ◽  
pp. 217-218 ◽  
Author(s):  
Wendy Klein-Schwartz ◽  
Richard Gorman ◽  
Gary M. Oderda ◽  
Azam Baig

1992 ◽  
Vol 76 (6) ◽  
pp. 1051-1053 ◽  
Author(s):  
J. M. SAISSY ◽  
M. VITRIS ◽  
J. DEMAZIÈRE ◽  
M. SECK ◽  
L. MARCOUX ◽  
...  

1981 ◽  
Vol 314 (6) ◽  
pp. 503-507 ◽  
Author(s):  
Shambhuling B. Havanur ◽  
Bharati V. Badami ◽  
Gurubasav S. Puranik

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