Systemic Paraphenylenediamine (PPD) Poisoning: A Case Report and Review

1994 ◽  
Vol 13 (3) ◽  
pp. 167-170 ◽  
Author(s):  
Waseem Ashraf ◽  
Shiela Dawling ◽  
Lew J. Farrow

A case of suicidal poisoning with paraphenylenediamine (PPD) is reported. The patient presented with typical features of severe oropharyngeal oedema and rhabdomyolysis, He suffered sudden cardiac death within 4 hours of admission despite full supportive treatment. The diagnosis was only established after his death. Systemic poisoning with paraphenylenediamine (PPD) is rare in western countries, and therefore a high degree of awareness and circumstantial evidence is required to make an early diagnosis. The classical and other less commonly reported features of this poisoning are discussed. There is no specific antidote available but some guidelines for management of such a case are reviewed.

2018 ◽  
Vol 117 (10) ◽  
pp. 939-943 ◽  
Author(s):  
Jen-Fang Cheng ◽  
Sze-Hwei Lee ◽  
Ron-Bin Hsu ◽  
Shan-Chi Yu ◽  
Chia-Tung Shun ◽  
...  

2020 ◽  
Vol 4 (2) ◽  
pp. 251-254
Author(s):  
Alexander Nguyen ◽  
Mario Flores ◽  
Vilmogil Tano

Introduction: Brugada syndrome is a genetic disorder of the heart’s electrical system that increases a patient’s risk of sudden cardiac death. It is a syndrome most prevalent in Southeast Asians and is found 36 times more commonly in Asians than in Hispanics. Case Report: We report and discuss a case of a 68-year-old Hispanic male who presented with clinical and electrocardiogram abnormalities consistent with Brugada syndrome. Discussion: The patient’s age and ethnicity represents an atypical presentation of this rare syndrome and the lack of reported studies in the literature pertaining to these demographics reflect this. Conclusion: Further studies and characterizations are necessary as manifestations continue to be unearthed. As such, Brugada Syndrome should be considered in the differential diagnosis for a myriad of patient populations.


2020 ◽  
Vol 22 (Supplement_E) ◽  
pp. E20-E24 ◽  
Author(s):  
Cristina Basso ◽  
Stefania Rizzo ◽  
Elisa Carturan ◽  
Kalliopi Pilichou ◽  
Gaetano Thiene

Abstract In the Western Countries, cardiovascular diseases are still the most frequent cause of death, which is often sudden. Sudden death (SD) in the young population occurs at a rate of 1/100 000/year and carries a profound social impact both for the young age of the victims and the unanticipated occurrence. Physical effort is a triggering risk factor, in fact SD occurs three times more frequently in athletes than in non-athletes. The screening for sport activity fitness can identify apparently healthy subjects carrying a silent abnormality able to trigger sudden cardiac death during sport activity, thus the fitness screening could be lifesaving. The spectrum of cardiovascular conditions identified at post-mortem examination is quite extensive, and include: coronary, myocardial, valvular diseases, as well as conduction system abnormalities. In 20% of the cases, the heart is normal, and sudden cardiac death is ascribed to ionic channel disease. The diagnosis of cardiomyopathy is possible with the integration of electrocardiogram and echography, thus decreasing significantly the occurrence of SD of athletes in Italy, but early diagnosis of coronary artery disease still remains challenging. The best strategy to further decrease sudden cardiac death during sport activities consists in combining early diagnosis with widespread availability of defibrillators on site.


2019 ◽  
Vol 4 (3) ◽  
pp. 267-273 ◽  
Author(s):  
Ana Isabel Hernández-Guerra ◽  
Javier Tapia ◽  
Luis Manuel Menéndez-Quintanal ◽  
Joaquín S. Lucena

1997 ◽  
Vol 37 (2) ◽  
pp. 170-175 ◽  
Author(s):  
Anil Kumar

Psychotropic drug use has long been associated with sudden unexplained and unexpected death in psychiatric patients despite controversies surrounding the issue. Physical restraint following violent episodes in psychiatric in-patients is also associated with neurally mediated sudden cardiac death. A case where these two mechanisms have jointly resulted in sudden death is reported. The literature on the subject is reviewed and the measures which may be useful in reducing the incidence of such deaths are discussed. The need for accurate and detailed reporting of such cases is emphasized.


2014 ◽  
Vol 17 (3) ◽  
pp. 231-239 ◽  
Author(s):  
Bin Xu ◽  
Richard S. Fraser ◽  
Claudia Renaud ◽  
Sameh Youssef ◽  
Ronald D. Gottesman ◽  
...  

2019 ◽  
Vol 04 (01) ◽  
Author(s):  
José Edgar Cervantes-Navarro ◽  
Jorge Ayón-Aguilar ◽  
Ernesto López-Luna ◽  
Jander Narváez-Acosta ◽  
Anita Gutiérrez-Romero

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