Mediastinal Immature Teratoma with Yolk Sac Tumor and MyelomonocyticLeukemia Associated with Klinefelter's Syndrome

2002 ◽  
Vol 10 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Dhirendra Govender ◽  
Shunmugam V. Pillay
Keyword(s):  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome

Case Reports: Primary Yolk Sac Tumor of the Prostate in a Patient With Klinefelter's Syndrome

1995 ◽  
Vol 153 (3S) ◽  
pp. 1066-1069 ◽  
Author(s):  
Howard P. Tay ◽  
Mohamed Bidair ◽  
Ahmed Shabaik ◽  
James H. Gilbaugh ◽  
Joseph D. Schmidt
Keyword(s):  
Case Reports ◽  
Yolk Sac ◽  
Yolk Sac Tumor ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome

scholarly journals Mediastinal mixed germ cell tumor: A case report and literature review

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 892-898
Author(s):  
Xianwen Hu ◽  
Dandan Li ◽  
Jinhua Xia ◽  
Pan Wang ◽  
Jiong Cai
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumor ◽  
Embryonal Carcinoma ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Medical Attention ◽  
Ct Guided ◽  
Mixed Germ Cell Tumor

Abstract Mixed germ cell tumor (MGCT) mainly occurs in young women’s ovaries and men’s testicles and rarely occurs outside the gonad. Fewer than 10 cases of mediastinal MGCT are available in PubMed, Embase, and other databases in English, while mediastinal MGCT with three pathological components, such as yolk sac tumor, immature teratoma, and embryonal carcinoma, has not been reported previously. A 12-year-old male sought medical attention for chest discomfort and underwent a computed tomography (CT) scan. A large soft tissue mass occupying most of the left thoracic cavity and mediastinum was detected. A CT-guided biopsy was performed, and an MGCT was diagnosed with pathological components, including yolk sac tumor, immature teratoma, and a small amount of embryonal carcinoma. Due to the large size of the tumor, the patient was treated with an EP regimen (etoposide + cisplatin) and paclitaxel + ifosfamide + cisplatin interstitial chemotherapy. The patient was followed up for 6 months and was alive with the disease. To the best of our knowledge, this is the 10th patient with MGCT in the mediastinum. The incidence of mediastinal MGCT is low, but it should still be considered one of the differential diagnoses of isolated pleural fibroma and neurogenic tumors.

scholarly journals Ovarian Yolk Sac Tumor: A Case Report with Review Of Literature

2016 ◽  
Vol 2 (1) ◽  
pp. 15-17
Author(s):  
A Sreehari ◽  
BM Rupakala
Keyword(s):  
Case Report ◽  
Early Adulthood ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Histological Subtype ◽  
Review Of Literature ◽  
Yolk Sac Tumors ◽  
Ovarian Dysgerminoma

ABSTRACT A total of 3 to 5% of all ovarian malignancies include malignant ovarian germ cell tumors (MOGCTs). They are subdivided into germinomatous and non-germinomatous tumors. Common types of non-germinomatous tumors include yolk sac and immature teratoma. Ovarian yolk sac tumors (YST) are the second most frequent histological subtype of MOGCTs, after ovarian dysgerminoma. They account for 20% of MOGCTs and are frequent especially in childhood and in early adulthood. We report the case of a yolk sac tumor of the ovary in a 13yrs years old female. How to cite this article Sreehari A, Rupakala BM, Sarojamma C. Ovarian Yolk Sac Tumor: A Case Report with Review of Literature. J Med Sci 2016;2(1):15-17.

scholarly journals A CASE OF IMMATURE TERATOMA AND YOLK SAC TUMOR OF THE TESTIS ASSOCIATED WITH PULMONARY METASTASES OF 2 DISTINCT HISTOLOGICAL TYPES

1994 ◽  
Vol 85 (2) ◽  
pp. 346-349
Author(s):  
Munehisa Ueno ◽  
Hitoshi Yanaihara ◽  
Nobuhiro Deguchi ◽  
Hiroshi Tazaki ◽  
Atsushi Uchida ◽  
...  
Keyword(s):  
Pulmonary Metastases ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Histological Types

scholarly journals Immature teratoma with microscopic yolk sac tumor: A case of diagnostic challenge on histology

2016 ◽  
Vol 5 (1) ◽  
pp. 19
Author(s):  
SonaliR Saraf ◽  
Madhu Chaturvedi ◽  
Manisha Khare ◽  
Alka Kalgutkar
Keyword(s):  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Diagnostic Challenge

scholarly journals Are omentectomy and lymphadenectomy necessary in patients with apparently early-stage malignant ovarian germ cell tumors?

2019 ◽  
Vol 29 (2) ◽  
pp. 398-403 ◽  
Author(s):  
Beijiao Qin ◽  
Wenyan Xu ◽  
Yanfang Li
Keyword(s):  
Prognostic Factors ◽  
Germ Cell ◽  
Early Stage ◽  
Survival Rates ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Cancer Center ◽  
Early Stage Disease

ObjectiveTo evaluate the role of omentectomy and lymphadenectomy in the treatment of clinically apparent early-stage malignant ovarian germ cell tumors.MethodsWe retrospectively reviewed 245 patients with malignant ovarian germ cell tumors (yolk sac tumor, dysgerminoma, and immature teratoma) and with clinically early-stage disease, who were treated at Sun Yat-sen University Cancer Center between January 1, 1970 and December 31, 2017. The survival of patients who underwent either omentectomy or lymphadenectomy, or both (omentectomy/lymphadenectomy group) was compared with that of patients who did not undergo omentectomy or lymphadenectomy (non-omentectomy/lymphadenectomy group).ResultsSixty patients were diagnosed with yolk sac tumor, 74 with dysgerminoma, and 111 with immature teratoma. Of these 245 patients, 216 patients had stage I disease, 28 patients had stage II, and 1 patient had stage IIIA. There were 190 patients who underwent omentectomy and/or lymphadenectomy and 55 patients in the non-omentectomy/lymphadenectomy group, respectively. In the omentectomy/lymphadenectomy group, 112 patients underwent both omentectomy and lymphadenectomy, 71 underwent omentectomy only, and 7 underwent lymphadenectomy only. Two hundred and fourteen of 245 patients (87.3%) received post-operative chemotherapy. Median follow-up was 73 months (range 1–388). The 10-year overall survival rates in the omentectomy/lymphadenectomy group and non-omentectomy/lymphadenectomy groups were 96.8% and 100%, respectively (p=0.340). Multivariate analysis evaluating all potential prognostic factors showed that omentectomy and lymphadenectomy are not prognostic factors for survival.ConclusionsOmentectomy and lymphadenectomy do not appear to improve survival and may be omitted in patients with clinically apparent early-stage malignant ovarian germ cell tumors.

scholarly journals A Case of Immature Teratoma with Yolk Sac Tumor Component Treated by Pleuropneumonectomy with Partial Resection of the Superior Vena Cava.

Haigan ◽  
1991 ◽  
Vol 31 (3) ◽  
pp. 415-420
Author(s):  
Hirohito Morita ◽  
Hirokuni Yoshimura ◽  
Saburo Hirai ◽  
Jyun Shinada ◽  
Akira Ishihara ◽  
...  
Keyword(s):  
Superior Vena Cava ◽  
Superior Vena ◽  
Vena Cava ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Partial Resection ◽  
Yolk Sac Tumor

scholarly journals GCT-18. CLINICAL FEATURES OF GERM CELL TUMORS IN CHILDREN

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii331-iii331
Author(s):  
Nayuta Higa
Keyword(s):  
Germ Cell ◽  
Clinical Features ◽  
Poor Prognosis ◽  
Embryonal Carcinoma ◽  
Germ Cell Tumors ◽  
Yolk Sac ◽  
Immature Teratoma ◽  
Yolk Sac Tumor ◽  
Study Patient ◽  
Third Ventriculostomy

Abstract INTRODUCTION Here, we discuss the presentation, histology, therapy, and outcome of germ cell tumors in children. METHODS Treatment outcome and management was assessed for children diagnosed with germ cell tumors from 2007 to 2017 at Kagoshima University. RESULTS Twenty-six patients (20 boys, 6 girls) with a mean age of 11.5 ± 4.9 years were included in this study. Patient tumor types included: germinoma (n = 19); immature teratoma (n = 3); yolk sac tumor (n = 3); choriocarcinoma (n = 1); embryonal carcinoma (n = 1). The most common patient clinical features were headache and vomiting associated with hydrocephalus. The median follow-up period was 96.5 months. Tumor location was pineal (n=9), bifocal (n=6), suprasellar (n = 5), basal ganglia (n=2), frontal lobe (n=2), and cerebellum (n=2). Surgical procedures included stereotactic biopsy (n=13), endoscopic third ventriculostomy and biopsy (n=8), and tumor decompression (n=5). All patients with germ cell tumors underwent adjuvant chemotherapy and radiation therapy; patients with germinoma or immature teratoma were still alive, while patients with embryonal carcinoma, yolk sac tumor, or choriocarcinoma had poor prognosis with a median survival of 16 months. CONCLUSIONS Patients with germinoma had a relatively good prognosis, while patients with embryonal carcinoma, yolk sac tumor, or choriocarcinoma had a poor prognosis. A multidisciplinary approach including surgical strategy based on location, appropriate radiation planning, and chemotherapy is needed for effective treatment and improved outcomes.

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