Thyroid-Like Follicular Carcinoma of the Kidney With Extensive Sarcomatoid Differentiation: A Case Report and Review of the Literature

2019 ◽  
Vol 27 (6) ◽  
pp. 678-683 ◽  
Author(s):  
Taylor M. Jenkins ◽  
Jason Rosenbaum ◽  
Paul J. Zhang ◽  
Lauren E. Schwartz ◽  
Anupma Nayak ◽  
...  
Keyword(s):  
Case Report ◽  
Follicular Carcinoma ◽  
Good Prognosis ◽  
Molecular Profile ◽  
Review Of The Literature ◽  
Course Of Disease ◽  
Targeted Next Generation Sequencing ◽  
Poorly Differentiated ◽  
Generation Sequencing ◽  
Sarcomatoid Differentiation

Thyroid-like follicular carcinoma of the kidney (TLFCK) is an extremely rare primary renal malignancy that typically has an indolent course and good prognosis. Histologically, this tumor mimics follicular carcinoma of the thyroid; however, typical thyroid markers are negative. There are fewer than 40 cases reported in the literature, and thus, the prognosis and course of disease is not well understood. Sarcomatoid differentiation has never been reported in a case of TLFCK. We present a case of a 48-year-old woman with an aggressive TLFCK with extensive sarcomatoid differentiation and metastatic disease at presentation. We performed targeted next-generation sequencing of both the thyroid-like component and the poorly differentiated sarcomatoid component using our solid tumor panel to evaluate for any disease-associated mutations and to better understand the molecular profile of these tumors.

scholarly journals Angiosarcoma of the Heart: Case Report

2020 ◽  
Vol 3 (11) ◽  
pp. 01-07
Author(s):  
Marc Vanderheyden ◽  
Sofie Dhaeyer ◽  
Chirik Wah Lau ◽  
Vanessa Meert ◽  
Jan Leeman ◽  
...  
Keyword(s):  
Case Report ◽  
Malignant Tumors ◽  
Local Relapse ◽  
Review Of The Literature ◽  
Poor Survival ◽  
Right Heart ◽  
Course Of Disease ◽  
Metastatic Recurrence ◽  
Primary Angiosarcoma ◽  
The Right

Cardiac angiosarcomas are rare malignant tumors, predominantly affecting the right heart with poor survival outcomes. The current mainstay of treatment consists of surgery with or without chemotherapy, but often yields limited results with local relapse or metastatic recurrence. This case report describes 2 patients with primary angiosarcoma located in the right atrium. One patient received neo-adjuvant and adjuvant chemotherapy; both were scheduled for surgical resection. The course of disease is described followed by a comprehensive review of the literature.

scholarly journals Thyroid-Like Follicular Carcinoma of the Kidney: One Case Report and Review of the Literature

2015 ◽  
Vol 144 (5) ◽  
pp. 796-804 ◽  
Author(s):  
Rahul Dawane ◽  
Alan Grindstaff ◽  
Anil V. Parwani ◽  
Timothy Brock ◽  
Wesley M. White ◽  
...  
Keyword(s):  
Case Report ◽  
Follicular Carcinoma ◽  
Review Of The Literature

scholarly journals Cervical Intramedullary Schwannoma: Case Report and Review of the Literature

2018 ◽  
Vol 10 (1) ◽  
pp. 18-24 ◽  
Author(s):  
José Omar Navarro Fernández ◽  
Alejandro Monroy Sosa ◽  
Bernardo Cacho Díaz ◽  
Víctor Andrés Arrieta ◽  
Ramses Uriel Ortíz Leyva ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Male Patient ◽  
Therapeutic Option ◽  
Good Prognosis ◽  
Review Of The Literature ◽  
Total Resection ◽  
Intramedullary Schwannoma

Cervical intramedullary schwannomas are extraordinarily rare. Gross total resection is the best therapeutic option for these types of tumors. Although rare, intramedullary schwannomas should be considered as a differential diagnosis of intramedullary lesions since a good prognosis can be guaranteed to the majority of these patients. We present a case of a cervical intramedullary schwannoma surgically treated in a 19-year-old male patient who initially presented with motor neuron disease.

Sign in / Sign up

Export Citation Format

Share Document