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ABSTRACT The parieto-occipital region of the brain is the most frequently and severely affected in subacute sclerosing panencephalitis (SSPE). The basal ganglia, cerebellum and corpus callosum are less commonly involved. We describe a patient with SSPE confirmed by neuropathology based on brain magnetic resonance imaging showing extensive basal ganglia involvement and no significant involvement of other cortical structures. Though rarely described in SSPE, clinicians should be aware of this involvement. SSPE should be kept in mind when changes in basal ganglia signal are seen on brain magnetic resonance imaging with or without involvement of other regions of the human brain to avoid erroneous etiological diagnosis of other pathologies causing rapidly progressive dementia.

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T1-weighted Hyperintensity in Basal Ganglia at Brain Magnetic Resonance Imaging:

NeuroToxicology ◽

10.1016/s0161-813x(02)00016-5 ◽

2002 ◽

Vol 23 (6) ◽

pp. 669-674 ◽

Cited By ~ 31

Author(s):

Elena Herrero Hernandez ◽

Maria Consuelo Valentini ◽

Gianluigi Discalzi

Keyword(s):

Magnetic Resonance Imaging ◽

Basal Ganglia ◽

Magnetic Resonance ◽

Brain Magnetic Resonance Imaging ◽

Resonance Imaging

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Dravet syndrome Presenting with Extrapyramidal Features, Ataxia and Basal Ganglia Hyperintensity on Brain Magnetic Resonance Imaging

Annals of Indian Academy of Neurology ◽

10.4103/aian.aian_1216_20 ◽

2021 ◽

Vol 0 (0) ◽

pp. 0

Author(s):

Mary Iype ◽

Mini Sreedharan ◽

ShahanazM. Ahamed ◽

ElizabethP. Thomas ◽

Merin Eapen ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Basal Ganglia ◽

Magnetic Resonance ◽

Brain Magnetic Resonance Imaging ◽

Dravet Syndrome ◽

Resonance Imaging ◽

Extrapyramidal Features

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Transient Brain Magnetic Resonance Imaging Hyperintensity in Basal Ganglia and Brain Stem of Epileptic Infants Treated With Vigabatrin

Journal of Child Neurology ◽

10.1177/0883073808324219 ◽

2009 ◽

Vol 24 (3) ◽

pp. 305-315 ◽

Cited By ~ 23

Author(s):

Mathieu Milh ◽

Nathalie Villeneuve ◽

Fréderique Chapon ◽

Sandrine Pineau ◽

Sylvie Lamoureux ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Basal Ganglia ◽

Magnetic Resonance ◽

Brain Stem ◽

Brain Magnetic Resonance Imaging ◽

Resonance Imaging

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Eye of the Tiger: Looking Beyond Neurodegeneration with Brain Iron Accumulation Disorders

Journal of Pediatric Genetics ◽

10.1055/s-0041-1723959 ◽

2021 ◽

Author(s):

Prajnya Ranganath ◽

Mallikarjun Patil

Keyword(s):

Magnetic Resonance Imaging ◽

Basal Ganglia ◽

Magnetic Resonance ◽

Neurodegenerative Disorders ◽

Brain Magnetic Resonance Imaging ◽

Iron Accumulation ◽

Resonance Imaging ◽

Brain Iron ◽

Mri Brain ◽

Magnetic Resonance Imaging Mri

AbstractThe “eye-of-the-tiger” sign in brain magnetic resonance imaging (MRI) is typically associated with neurodegeneration with brain iron accumulation disorders, especially pantothenate kinase-associated neurodegeneration. However, very similar neuroimaging findings may be seen in other neurodegenerative disorders involving the basal ganglia. We report here a patient with fucosidosis who had MRI brain findings closely resembling the “eye-of-the-tiger” sign.

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