Unexpected Complication of Hydroxocobalamin Administration for Refractory Vasoplegia in Orthotopic Liver Transplant: A Case Report

2019 ◽  
Vol 23 (4) ◽  
pp. 409-412 ◽  
Author(s):  
Cara Crouch ◽  
Adrian Hendrickse ◽  
Samuel Gilliland ◽  
M. Susan Mandell
Keyword(s):  
Intensive Care Unit ◽  
Liver Transplantation ◽  
Kidney Transplantation ◽  
End Stage Renal Disease ◽  
Alcoholic Cirrhosis ◽  
Refractory Hypotension ◽  
Liver And Kidney ◽  
Stage Renal Disease ◽  
End Stage ◽  
Hemodialysis Machine

A 40-year-old male with alcoholic cirrhosis and end-stage renal disease presented for simultaneous liver and kidney transplantation. Hemodialysis was utilized intraoperatively during liver transplantation. During the procedure, the patient developed refractory hypotension and ultimately received hydroxocobalamin for vasoplegia. Shortly after administration, the hemodialysis machine ceased working after a “blood leak” alarm developed. Without the ability to continue intraoperative dialysis, the kidney transplantation portion of his surgery was postponed. The patient was transferred to the intensive care unit, where he underwent continuous renal replacement therapy overnight, and his kidney transplant proceeded the following morning.

scholarly journals Multidisciplinary Cooperation in a Simultaneous Combined Liver and Kidney Transplantation Patient of Primary Hyperoxaluria

2017 ◽  
Vol 56 (205) ◽  
pp. 175-178
Author(s):  
Ren Qingqi ◽  
Ju Weiqiang ◽  
Wang Dongping ◽  
Guo Zhiyong ◽  
Chen Maogen ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Primary Hyperoxaluria ◽  
Multidisciplinary Cooperation ◽  
Liver And Kidney ◽  
Stage Renal Disease ◽  
End Stage ◽  
Hyperoxaluria Type

Primary hyperoxaluria type 1 is an autosomal recessive hereditary glyoxylate metabolism disorder characterized by excessive production of oxalate, caused by the deficiency of liver specific peroxisomal enzyme: alanineglyoxylate aminotransferase. For patients with end-stage renal disease, combined liver and kidney transplantation was needed. This report describes one patient, with a diagnosis of end-stage renal disease and primary hyperoxaluria 1 confirmed by PCR and direct sequencing with genomic DNA, received the simultaneous combined liver and kidney transplantation after seven months’ waiting. However, there were several complications observed post surgery, such as protracted bleeding, common bile duct anastomotic stenosis, biliary calculi and recurrence of urolithiasis. All these were well solved by relevant department, and finally a satisfactory outcome was achieved. Multidisciplinary cooperation plays an important role on the PH1 patient management, especially when multiple complications are encountered. Keywords: primary hyperoxaluria type 1; end-stage renal disease; liver transplantation; kidney transplantation.

scholarly journals Decompensated Cirrhosis after Renal Transplantation: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Vinay Patel ◽  
Luis Marsano ◽  
Mary Eng
Keyword(s):  
Liver Transplantation ◽  
Renal Failure ◽  
Kidney Transplantation ◽  
Case Report ◽  
Renal Transplantation ◽  
End Stage Renal Disease ◽  
Decompensated Cirrhosis ◽  
End Stage Liver Disease ◽  
Stage Renal Disease ◽  
End Stage

Patients with end-stage liver disease with renal failure can be considered for simultaneous liver kidney transplantation. There are, however, no clear guidelines as to the management of the well-compensated cirrhotic patient with end-stage renal disease. We present the case of a patient with cirrhosis who decompensated after renal transplantation. With no indication for liver transplantation, can these patients safely undergo renal transplantation?

scholarly journals Effects of renal transplantation on erectile dysfunction: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Irham Arif Rahman ◽  
Nur Rasyid ◽  
Ponco Birowo ◽  
Widi Atmoko
Keyword(s):  
Systematic Review ◽  
Erectile Dysfunction ◽  
Kidney Transplantation ◽  
Renal Transplantation ◽  
End Stage Renal Disease ◽  
Erectile Function ◽  
Meta Analysis ◽  
Post Transplantation ◽  
Stage Renal Disease ◽  
End Stage

AbstractErectile dysfunction (ED) is a major global health burden commonly observed in patients with end-stage renal disease (ESRD). Although renal transplantation improves the problem in some patients, it persists in ≈20–50% of recipients. Studies regarding the effects of kidney transplantation on ED present contradictory findings. We performed a systematic review to summarise the effects of kidney transplantation on ED. A systematic literature search was performed across PubMed, Cochrane, and Scopus databases in April 2020. We included all prospective studies that investigated the pre and posttransplant international index of erectile function (IIEF-5) scores in recipients with ED. Data search in PubMed and Google Scholar produced 1326 articles; eight were systematically reviewed with a total of 448 subjects. Meta-analysis of IIEF-5 scores showed significant improvements between pre and post transplantation. Our findings confirm that renal transplantation improves erectile function. Furthermore, transplantation also increases testosterone level. However, the evidence is limited because of the small number of studies. Further studies are required to investigate the effects of renal transplantation on erectile function.

scholarly journals Significant Decrease in Plasma N-Acetyl-seryl-aspartyl-lysyl-proline Level in Patients with End Stage Renal Disease after Kidney Transplantation

2014 ◽  
Vol 37 (6) ◽  
pp. 1075-1079 ◽  
Author(s):  
Yosuke Suzuki ◽  
Fumihiko Katagiri ◽  
Fuminori Sato ◽  
Kanako Fujioka ◽  
Yukie Sato ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Proline Level ◽  
Stage Renal Disease ◽  
End Stage
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