New Findings in the Parry-Romberg Syndrome: A Case Report

2002 ◽  
Vol 12 (6) ◽  
pp. 556-558 ◽  
Author(s):  
F. Bandello ◽  
N. Rosa ◽  
F. Ghisolfi ◽  
A. Sebastiani
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Clinical Observation ◽  
Clinical History ◽  
Extraocular Muscles ◽  
Hemifacial Atrophy ◽  
New Findings ◽  
History Of ◽  
Parry Romberg Syndrome ◽  
Light Staining

Purpose To describe further findings in the Parry-Romberg syndrome that might contribute towards a better understanding of the disease. Design Case report. Methods The clinical history of a patient with the Parry-Romberg syndrome was studied, and fluorangiography and echography were carried out. Results Clinical observation revealed classic hemifacial atrophy; fluorescein angiography showed teleangectases, light staining of the retina, and leakage from the largest teleangectasis and the optic disc vessels; echography showed shrinkage of the eyeball and thinning of the extraocular muscles. Conclusions Enophthalmos in this disease is caused not only by progressive fat atrophy but also by shrinkage of the eyeball and thinning of the extraocular muscles; the shrinkage of the eyeball helps explain the presence of choroidal and retinal folding and hyperopia, confirming the primary involvement of connective tissue in this disease.

scholarly journals Metastatic Pancreatic Cancer with BRAF and P53 Mutations: Case Report of Therapeutic Response to Doublet Targeted Therapy

2020 ◽  
Vol 13 (3) ◽  
pp. 1239-1243
Author(s):  
Shenthol Sasankan ◽  
Lorraine Rebuck ◽  
Gloria Darrah ◽  
Moises Harari Turquie ◽  
Ian Rabinowitz
Keyword(s):  
Pancreatic Cancer ◽  
Case Report ◽  
Targeted Therapy ◽  
Therapeutic Response ◽  
Case Reports ◽  
Clinical History ◽  
P53 Mutation ◽  
Metastatic Pancreatic Cancer ◽  
First Case ◽  
History Of

We report on the clinical history of a 49-year-old female with metastatic pancreatic cancer. She was initially treated with standard chemotherapy as per current guidelines. She was found to have both a BRAF and P53 mutation, and received dabrafenib and trametinib with deep responses, both radiographically and biochemically (CA19-9). Her response has been more clinically relevant than responses in previous case reports of patients with BRAF-positive pancreatic cancer treated with targeted therapy. To the best of our knowledge, this is the first case report showing a dramatic therapeutic response to combination therapy with dabrafenib and trametinib in metastatic pancreatic cancer.

Cycloid Psychosis: A Case Report

2016 ◽  
Vol 33 (S1) ◽  
pp. S532-S532
Author(s):  
G. Martinez-Ales ◽  
I. Louzao ◽  
A. Irimia ◽  
M.F. Bravo ◽  
J. Marin
Keyword(s):  
Case Report ◽  
Psychotic Disorders ◽  
Clinical History ◽  
Diagnostic Systems ◽  
Cycloid Psychosis ◽  
History Of ◽  
Competing Interest ◽  
High Index Of Suspicion ◽  
Clinical Pictures ◽  
Restitutio Ad Integrum

IntroductionEpisodes of time-limited acute psychosis, with full recovery in between, are categorized as acute polymorphic psychotic or brief psychotic disorders. Leonhard described the three forms of cycloid psychosis (CP). Perry considers it a separate entity.Case reportWe report the case of a 54-year-old male, with a 9-year history of brief psychotic disorders. He was admitted to an inpatient unit after a 4-day episode of persecutory delusion, leading to high emotional repercussions and isolation at home. Euthymia was present. Previous admissions, 9 and 5 years before, presented similar clinical pictures. Treatment with low dose paliperidone during 6-month periods had led to the complete resolution of the episodes (restitutio ad integrum: no psychotic manifestations and the ability to run his business). In this episode, 8 days after the reintroduction of 12 mg of paliperidone per day, cessation of the symptoms took place. Careful reconstruction of the clinical history showed no stressors or drug consumption. And immediately previous 5-day phase of insomnia, hyperactivity and expenditure was described by the patient's wife.DiscussionThree inpatient admissions, a careful clinical history and a thorough review of the evidence regarding Perris criteria led to a diagnosis of CP.ConclusionCP, a classical nosological approach, is helpful in a clinical setting, as it might imply different prognosis and treatment. Recognition of CP, not included as an entity by the major diagnostic systems, requires a high index of suspicion.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Polyarticular Septic Arthritis with Bilateral Psoas Abscesses following Acupuncture

2009 ◽  
Vol 27 (2) ◽  
pp. 81-82 ◽  
Author(s):  
Michihiro Ogasawara ◽  
Keisuke Oda ◽  
Ken Yamaji ◽  
Yoshinari Takasaki
Keyword(s):  
Staphylococcus Aureus ◽  
Case Report ◽  
Septic Arthritis ◽  
Acupuncture Treatment ◽  
Psoas Abscess ◽  
Clinical History ◽  
Chronic Lower Back Pain ◽  
Lower Back ◽  
History Of ◽  
Long Course

We report a case of polyarticular septic arthritis with bilateral psoas abscesses. A 50-year-old woman was admitted with fever, multiple joint swelling and pain. She had a clinical history of acupuncture therapy for treatment of her chronic lower back pain two days before the appearance of her symptoms. Methicillin-sensitive Staphylococcus aureus was isolated from blood culture, knee joint fluids and psoas abscess. After a long course of antibiotics for 70 days together with drainage of the abscess, the condition completely resolved. The acupuncture is the probable cause of the infection, and this case report reveals the importance of asking about a clinical history of acupuncture treatment and of making repeated bacterial examinations in undiagnosed polyarthritis patients.

TREATMENT OF PROGRESSIVE HEMIFACIALATROPHY (PARRYROMBERG SYNDROME) WITH POLYMETHYL METHACRYLATE: A CASE REPORT.

2020 ◽  
pp. 1-2
Author(s):  
Roberto Chacur ◽  
Honório Sampaio Menezes ◽  
Nívea Maria Bordin da Silva Chacur ◽  
Danuza Dias Alves ◽  
Rodrigo Cadore Mafaldo ◽  
...  
Keyword(s):  
Case Report ◽  
Polymethyl Methacrylate ◽  
Hemifacial Atrophy ◽  
Aesthetic Result ◽  
Tissue Augmentation ◽  
Progressive Hemifacial Atrophy ◽  
Subcutaneous Layer ◽  
Parry Romberg Syndrome ◽  
Good Aesthetic Result

Progressive hemifacial atrophy, also called Parry-Romberg Syndrome (PRS), is a craniofacial disorder that typically involves the subcutaneous layer of one side of the face.This article We reports a case of a patient treated with polymethylmethacrylate for tissue augmentation and facial volume recovering asymmetry. Polymethylmethacrylate is effective and safe for treating progressive hemifacial atrophy and can leads a good aesthetic result.

Connective Tissue Graft as a Predictable Curtain for Aesthetics: A Case Report

2021 ◽  
Vol 10 (1) ◽  
pp. 63-66
Author(s):  
Simant Lamichhane ◽  
Manoj Humagain ◽  
Asmita Dawadi
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Dental Implants ◽  
Dental Implant ◽  
Clinical Signs ◽  
Coronally Advanced Flap ◽  
Connective Tissue Graft ◽  
Tissue Graft ◽  
Intact Bone ◽  
History Of

  Dental implant practice has now become a major choice for replacement of missing teeth in modern dentistry. Over the years, the success rate of dental implants has increased from 80-90% to 96-98%. However, due to lack of proper availability of soft tissue and hard tissue along with improper alignment of dental implants often pose aesthetic concerns in anterior aesthetic zone though the implant is fully osseointegrated with no signs of clinical mobility. This case report presents a case of a 21 years old male with a history of tooth loss due to trauma 8 months back and rehabilitation with dental implant 6 months back. On examination, mid-labial recession of around 3mm associated with #11 with no clinical signs of overlying inflammation was noted. Intact bone support was revealed by IOPAR. The recessed area around dental implant was managed with connective tissue graft and coronally advanced flap.

scholarly journals A case report of exophytic nasal papilloma with acute dacryocystitis as the first symptom

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ya Mo ◽  
Danning Long ◽  
Luoxiang Li ◽  
Yanlin Zheng
Keyword(s):  
Case Report ◽  
General Anesthesia ◽  
Malignant Transformation ◽  
Benign Tumor ◽  
Clinical Observation ◽  
Purulent Discharge ◽  
Lacrimal Sac ◽  
Case Presentation ◽  
History Of ◽  
The Right

Abstract Background This study aims to explore a case of exophytic nasal papilloma with acute dacryocystitis as the first symptom. Case presentation A 72-year-old male patient complaining of “a 10-year history of tearing and purulent discharge from the right eye, with subsequent redness and pain in the inner canthus for three days” was initially diagnosed with acute dacryocystitis of the right eye. The patient was treated with anti-inflammatory therapy. However, the redness and swelling of the inner canthus continued to increase. An endoscopic dacryocystorhinostomy of the right eye was performed under general anesthesia. A large amount of purulent secretion was drained during the operation. As a result, the swelling of the inner canthus was significantly reduced. A routine intra-operative biopsy of the wall of the lacrimal sac revealed an exophytic nasal papilloma. A second biopsy, 1 week after the surgery, revealed the same result. The patient was advised to undergo a dacryocystectomy once the swelling had subsided. However, the patient was reluctant to undergo this surgery and remains under clinical observation. Conclusion It is rare for an exophytic nasal papilloma, which is a benign tumor in the lacrimal sac, which has the potential for recurrence and malignant transformation, to manifest with acute dacryocystitis as the first symptom. Therefore, this case report could provide a reference for the future clinical diagnosis of this disease.

scholarly journals Severe oropharyngeal dysphagia following COVID-19: a case report

2020 ◽  
Author(s):  
Giulia De Vincentis ◽  
Chiara Ferrari ◽  
Dario Guerini Rocco
Keyword(s):  
Case Report ◽  
Oropharyngeal Dysphagia ◽  
Vocal Folds ◽  
Clinical History ◽  
Rehabilitation Treatment ◽  
Severe Dysphagia ◽  
History Of ◽  
First Time ◽  
Intensive Rehabilitation

This case report describes the clinical history of a COVID-19 patient with a non-immediate diagnosis of severe dysphagia that required a gastrostomy positioning. A vocal folds paresis was observed for the first time in the course of a Sars-CoV-2 infection. Thanks to intensive rehabilitation treatment, the outcome was favourable.

scholarly journals Wound infection caused by Neisseria zoodegmatis, a zoonotic pathogen: a case report

2021 ◽  
Author(s):  
John Merlino ◽  
Timothy Gray ◽  
Rohan Beresford ◽  
Sai Rupa Baskar ◽  
Thomas Gottlieb ◽  
...  
Keyword(s):  
Case Report ◽  
Type Species ◽  
Culture Media ◽  
Clinical History ◽  
Content Type ◽  
Zoonotic Pathogen ◽  
Link Type ◽  
Flight Mass Spectrometry ◽  
Clinical Laboratories ◽  
History Of

The isolation of Neisseria zoodegmatis from a 63-year-old female presenting to the emergency department following a cat bite injury to her right hand is described in this report. N. zoodegmatis , also known as Centers for Disease Control (CDC) group EF-4b, is considered to be a zoonotic pathogen, and is usually associated with dog or cat bites. Despite the potential of this organism to cause serious soft tissue infections, it can be overlooked in routine clinical laboratories due to its slow growth characteristics and when the history of animal bite is not provided to the laboratory. This case highlights the importance of appropriate clinical history provision to the microbiology laboratory to help provide important information about potential pathogens and allow microbiologists to optimize culture and identification methods. The introduction of tools such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) into clinical laboratories allows identification and the interpretation of results to be performed within a few minutes of isolation on proper culture media, as opposed to traditional methods, whose slowness may be problematic, as shown in this case report.

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