Factors Associated With Noninfectious Fever After Endovascular Aortic Aneurysm Repair

2021 ◽  
pp. 152660282110659
Author(s):  
Petroula Nana ◽  
Konstantinos Spanos ◽  
Konstantinos Dakis ◽  
Christos Karathanos ◽  
George Kouvelos ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Aortic Aneurysm ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Graft Material ◽  
Factors Associated ◽  
The Mean ◽  
Aneurysm Repair ◽  
The Impact ◽  
Aortic Aneurysm Repair

Purpose: The post–endovascular abdominal aortic aneurysm repair (EVAR) inflammatory response, which is very often associated with fever, has been ascribed to a wide range of proinflammatory mediators and operative events. The aim of this study was to evaluate the impact of such factors in the development of fever of noninfectious origin after elective EVAR. Materials and Methods: A retrospective analysis of prospectively collected data of patients treated with standard elective EVAR between February 2017 and December 2020 was undertaken. The database included patients’ demographics and comorbidities, as well as laboratory inflammatory markers (white blood cell count, neutrophils, and C-reactive protein [CRP]) and anatomical characteristics (sac diameter, inferior mesenteric artery [IMA] patency and diameter, number of patent lumbar arteries, internal iliac artery [IIA] patency or occlusion). Intraoperative details, such as type of stent graft material and IIA overstenting, were also analyzed. Patients with infectious postoperative complications or previously receiving systemic anti-inflammatory medication were excluded. Statistical analysis was performed by SPSS 22.0 for Windows software (IBM Corp, Armonk, New York). Results: From 332 patients treated with elective EVAR between 2017 and 2020, 268 patients (all men) were included in the analysis. The mean age was 72.1±7.5 years and the mean aneurysm diameter was 59.1±12.1 mm. Seventeen patients were excluded due to a known infection site. From the study cohort, 114 (42.5%) patients presented with fever. Multivariate regression analysis confirmed that the occlusion of IMA ≥5 mm (p<0.008) and higher CRP (p<0.001) were independent factors associated with postoperative fever. A subanalysis was performed only on patients with patent IMA before EVAR. In the multivariate regression analysis of this subgroup, IMA ≥5 mm (p=0.008), presence of dyslipidemia (p=0.037), and higher CRP (p<0.001) were related to fever. Conclusion: Occlusion of an existing wide (≥5 mm) and patent IMA prior to EVAR may contribute to the development of post-EVAR pyrexia. The CRP is a reliable marker for post-EVAR fever. Further prospective studies are needed to corroborate these findings.

scholarly journals Prolonged SARS-CoV-2 Viral Shedding in Patients with COVID-19 was Associated with Delayed Initiation of Arbidol Treatment: a retrospective cohort study

2020 ◽  
Author(s):  
Yaya Zhou ◽  
Xinliang He ◽  
Jianchu Zhang ◽  
Yu’e Xue ◽  
Mengyuan Liang ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Virus Shedding ◽  
Illness Onset ◽  
Factors Associated ◽  
Viral Shedding ◽  
Union Hospital ◽  
Delayed Initiation ◽  
The Impact

AbstractObjectivesEvaluate the risk factors of prolonged SARS-CoV-2 virus shedding and the impact of arbidol treatment on SARS-CoV-2 virus shedding.MethodsData were retrospective collected from adults hospitalized with COVID-19 in Wuhan Union Hospital. We described the clinical features and SARS-CoV-2 RNA shedding of patients with COVID-19 and evaluated factors associated with prolonged virus shedding by multivariate regression analysis.ResultsAmong 238 patients, the median age was 55.5 years, 57.1% were female, 92.9% (221/238) used arbidol, 58.4% (139/238) used arbidol combination with interferon. The median time from illness onset to start arbidol was 8 days (IQR, 5-14 days) and the median duration of SARS-CoV-2 virus shedding was 23 days (IQR, 17.8–30 days). SARS-CoV-2 RNA clearance was significantly delayed in patients who received arbidol >7 days after illness onset, compared with those in whom arbidol treatment was started≤7 days after illness onset (HR, 1.738 [95% CI, 1.339–2.257], P < .001). Multivariate regression analysis revealed that prolonged viral shedding was significantly associated with initiation arbidol more than seven days after symptom onset (OR 2.078, 95% CI [1.114-3.876], P .004), more than 7 days from onset of symptoms to first medical visitation (OR 3.321, 95% CI[1.559-7.073], P .002), illness onset before Jan.31, 2020 (OR 3.223, 95% CI[1.450-7.163], P .021). Arbidol combination with interferon was also significantly associated with shorter virus shedding (OR .402, 95% CI[.206-.787], P .008).ConclusionsEarly initiation of arbidol and arbidol combination with interferon as well as consulting doctor timely after illness onset were helpful for SARS-CoV-2 clearance.

Relation of Fatigue with Alexithymia and Depression in Psychiatric Outpatients

2007 ◽  
Vol 105 (2) ◽  
pp. 539-545
Author(s):  
Thomas N. Wise ◽  
Michael J. Sheridan
Keyword(s):  
Primary Care ◽  
Regression Analysis ◽  
Psychosocial Stress ◽  
Multivariate Regression ◽  
Multivariate Regression Analysis ◽  
Psychiatric Outpatients ◽  
The Mean

The complaint of fatigue is common in community, primary care, and psychiatric settings. Fatigue is often associated with depression and psychosocial stress. This report investigated the role of alexithymia and depression in fatigue as reported in a sample of 151 psychiatric outpatients (75 men and 76 women) who completed all scales. The mean age of the sample was 45.5 yr. ( SD = 12.5), and mean education was 16.2 yr. ( SD = 2.4). Fatigue was inversely correlated with education (–.16) and positively correlated with depression (.44), anxiety (.30), and alexithymia (.35). However, in a multivariate regression analysis, only depression and alexithymia remained significant ( p ≤ .01).

scholarly journals Evaluation of Decayed, Missing and Filled Teeth (DMFT) index in the 12 Years Old Students of Tehran City, Iran

2018 ◽  
Vol 17 ◽  
pp. e18888
Author(s):  
Azam Goodarzi ◽  
Alireza Heidarnia ◽  
Sedigheh Sadat Tavafian ◽  
Mohammad Eslami
Keyword(s):  
Regression Analysis ◽  
Dental Caries ◽  
Multivariate Regression ◽  
Family Income ◽  
Multivariate Regression Analysis ◽  
Analysis Model ◽  
Cross Sectional Survey ◽  
Related Factors ◽  
Dmft Index ◽  
The Mean

Aim: The main aim of this study was to Evaluate of Decayed, Missing and Filled Teeth (DMFT) Index in 12 Year Old Students of Tehran City, and to identify related factors that affect dental caries within this group. Methods: A cross-sectional survey was conducted among students of 12 years old in Tehran, Iran. Dental caries status was assessed in terms of decayed teeth (DT), filled teeth (FT) and decayed, missing and filled teeth (DMFT). “Data were analysed using SPSS version 22; a multivariate regression analysis was used to determine statistically significant associations between DMFT and other variables (p < 0.05). Results: A total of 416 respondents participated in the study. The mean age of the students was10.94 (SD=0.628) years, and the mean DMFT was 1.03 (SD=1.41). So that, in this study DT (0.53 ± 0.95) had the highest and MT (0.14 ± 0.47) had the lowest mean. A multivariate regression analysis model results showed a significant relation between high DMFT scores and such variables as increasing age, lower levels of mother's education, higher family income, lower frequency of tooth brushing and dental flossing, having a history of no visits to the dentist (P<0.05). Conclusion: The current study shows that Iranian female students have a poor oral health behavior, as very few subjects use dental floss on a regular basis. Although there appeared to be a significant relationship between caries scores and demographic factors such as age and socio-behavioral variables include  family income, the level of mothers' education, the frequency of dental brushing and flossing, and both the frequency and type of visit to a dentist.

Patient-Related Risk Factors Associated With Surgical Site Complications After Elective Hand Surgery

Hand ◽  
2020 ◽  
pp. 155894472094426
Author(s):  
Tyler Youngman ◽  
Michael Del Core ◽  
Timothy Benage ◽  
Daniel Koehler ◽  
Douglas Sammer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Regression Analysis ◽  
Surgical Complications ◽  
Multivariate Regression ◽  
Univariate Analysis ◽  
Hand Surgery ◽  
Multivariate Regression Analysis ◽  
Class Iii ◽  
Factors Associated ◽  
Surgical Site Complications

Background: The purpose of this study was to identify independent risk factors associated with an increased rate of surgical site complications after elective hand surgery. Methods: This study is a retrospective review of all patients who underwent elective hand, wrist, forearm, and elbow surgery over a 10-year period at a single institution. Electronic medical records were reviewed, and information regarding patient demographics, past medical and social history, perioperative laboratory values, procedures performed, and surgical complications was collected. Surgical site complications included surgical site infections, seromas or hematomas, and delayed wound healing or wound dehiscence. A univariate analysis was then performed to identify potential risk factors, which were then included in a multivariate regression analysis. Results: A total of 3261 patients who underwent elective hand surgery and met the above inclusion and exclusion criteria were included in this study. The mean age was 57 years, with 65% female and 35% male patients. The overall surgical complication rate was 2.2%. Univariate analysis of patient factors identified male sex; number of procedures >1; history of drug, alcohol, or smoking use; American Society of Anesthesiologists (ASA) class III and IV; and serum albumin <3.5 mg/dL to be significantly associated with complications. However, multivariate regression analysis identified that only ASA class III and IV (odds ratio = 3.27) was significantly associated with surgical complications. Conclusions: Patients classified as ASA class III or IV were identified to be at a significantly increased risk of complications following elective hand surgery. Health factors which triage patients into these 2 groups may represent potentially modifiable factors to mitigate perioperative risk in the elective hand surgery population.

scholarly journals Changes of the Macular Ganglion Cell-Inner Plexiform Layer Thickness after Cataract Surgery in Glaucoma Patients

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Hyun Cheol Roh ◽  
Choul Yong Park ◽  
Martha Kim
Keyword(s):  
Regression Analysis ◽  
Cataract Surgery ◽  
Ganglion Cell ◽  
Multivariate Regression ◽  
Linear Regression Analysis ◽  
Plexiform Layer ◽  
Multivariate Regression Analysis ◽  
Inner Plexiform Layer ◽  
Postoperative Changes ◽  
The Mean

Purpose. To investigate the effect of uneventful cataract surgery on macular ganglion cell-inner plexiform layer (mGC-IPL) thickness in glaucoma patients.Methods. This retrospective study included 65 eyes of 65 subjects who underwent uneventful cataract surgery, including 13 glaucoma eyes and 52 normal eyes. Using spectral domain optical coherence tomography, the mGC-IPL thickness was measured and compared between glaucoma and normal eyes preoperatively as well as 1 month and 3 months postoperatively. Linear regression analysis was used to determine the factors associated with postoperative change in mGC-IPL thickness.Results. The mean mGC-IPL significantly increased in both groups 1 month and 3 months after surgery (allPvalues equal to or less than 0.001). The postoperative changes between groups were not significantly different (P=0.171). In the multivariate regression analysis, preoperative mGC-IPL thickness showed a significant association with the change of average mGC-IPL thickness 1 month and 3 months after surgery (allPvalues < 0.001).Conclusions. The mean mGC-IPL thickness was increased after cataract surgery, and the postoperative mGC-IPL thickness changes were associated with preoperative mGC-IPL thickness in both groups and axial length in normal eye. The effects of cataract surgery on mean mGC-IPL thickness were not different in glaucomatous and normal eyes.

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