Endoleak as a Complication of Endoluminal Grafting of Abdominal Aortic Aneurysms: Classification, Incidence, Diagnosis, and Management

1997 ◽  
Vol 4 (2) ◽  
pp. 152-168 ◽  
Author(s):  
Geoffrey H. White ◽  
Weiyun Yu ◽  
James May ◽  
Xavier Chaufour ◽  
Michael S. Stephen
Keyword(s):  
Management Strategies ◽  
Clinical Trial Data ◽  
Diagnostic Techniques ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Collateral Arteries ◽  
Abdominal Aortic ◽  
Contrast Enhanced ◽  
Imaging Surveillance ◽  
Enhanced Computed Tomography

The inability to obtain or maintain a secure seal between a vessel wall and a transluminally implanted intra-aneurysmal graft is a complication unique to the evolving technique of endovascular aneurysm exclusion. Because the term “leak” has long been associated with aneurysm rupture, the term “endoleak” is proposed as a more definitive description of this phenomenon. Embracing both persistent blood flow into the aneurysmal sac from within or around the graft (graft related) and from patent collateral arteries (nongraft related), endoleak can be classified as primary or secondary depending on the time of occurrence (within 30 days of implantation or following apparent initial seal, respectively). Diagnostic techniques to detect endoleak include arteriography, intraprocedural pressure monitoring, contrast-enhanced computed tomography, abdominal X ray, and duplex scanning. Management strategies for endoleak range from observation with periodic imaging surveillance to correction by additional endoluminal or surgical procedures. Standardization of the terminology describing this important sequela to endovascular aneurysm exclusion should facilitate uniform reporting of clinical trial data vital to the evaluation of this emerging technique.

Endoluminal Repair of Abdominal Aortic Aneurysms: Strengths and Weaknesses of Various Prostheses Observed in a 4.5-Year Experience

1997 ◽  
Vol 4 (2) ◽  
pp. 147-151 ◽  
Author(s):  
James May ◽  
Geoffrey H. White ◽  
Weiyun Yu ◽  
Richard Waugh ◽  
Michael S. Stephen ◽  
...  
Keyword(s):  
Vascular Complications ◽  
Aortic Aneurysms ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Endoluminal Repair ◽  
Abdominal Aortic ◽  
Contrast Enhanced ◽  
Fluoroscopic Control ◽  
Enhanced Computed Tomography

Purpose: To summarize the results of endovascular abdominal aortic aneurysm (AAA) treatment using several endograft designs over a 4.5-year experience and offer comparisons on the various devices. Methods: From May 1992 to August 1996, 121 AAA patients meeting the criteria for an endoluminal repair were treated with 1 of 5 endograft designs in three configurations. The endografts were implanted in the operating room under fluoroscopic control. Follow-up included contrast-enhanced computed tomography within 10 days of operation, 6 months postoperatively, and annually thereafter. Results: Endografts were successfully deployed in 106 patients (88%). Fifteen cases were converted to open repair. Six procedure-related deaths occurred within 30 days owing to myocardial infarction (3), combined renal failure and septicemia (2), and multisystem failure (1). There were 36 local/vascular complications (30%) and 18 systemic/remote complications (15%). Of the 121 patients undergoing endoluminal AAA repair, 93 (77%) are currently alive and well with their AAAs excluded from the circulation. Conclusions: Trends in endoluminal AAA repair and prosthetic design point toward simpler devices and earlier treatment of smaller aneurysms once the long-term outcome of aortic endografting has been determined.

Flow-Induced Wall Pressure Under Average Resting Hemodynamic Conditions for Patient-Specific Abdominal Aortic Aneurysms

2002 ◽  
Author(s):  
Ender A. Finol ◽  
Shoreh Hajiloo ◽  
Keyvan Keyhani ◽  
David A. Vorp ◽  
Cristina H. Amon
Keyword(s):  
Imaging Techniques ◽  
Abdominal Aortic Aneurysms ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Mortality And Morbidity ◽  
Abdominal Aortic ◽  
Lethal Event ◽  
Overall Mortality

Abdominal Aortic Aneurysms (AAAs) are characterized by a continuous dilation of the infrarenal segment of the abdominal aorta. Despite significant improvements in surgical procedures and imaging techniques, the mortality and morbidity rates associated with untreated ruptured AAAs are still outrageously high. AAA disease is a health risk of significant importance since this kind of aneurysm is mostly asymptomatic until its rupture, which is frequently a lethal event with an overall mortality rate in the 80% to 90% range. From a purely biomechanical viewpoint, aneurysm rupture is a phenomenon that occurs when the mechanical stress acting on the dilating inner wall exceeds its failure strength. Since the internal mechanical forces are maintained by the dynamic action of blood flowing in the aorta, the quantification of the hemodynamics of AAAs is essential for the characterization of their biomechanical environment.

Successful Embolization of Persistent Endoleak from a Patent Inferior Mesenteric Artery

1997 ◽  
Vol 4 (3) ◽  
pp. 312-315 ◽  
Author(s):  
Greg van Schie ◽  
Kishore Sieunarine ◽  
Mike Holt ◽  
Michael Lawrence-Brown ◽  
David Hartley ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Abdominal Aortic Aneurysm ◽  
Mesenteric Artery ◽  
Inferior Mesenteric Artery ◽  
Abdominal Aortic ◽  
Contrast Enhanced ◽  
Retrograde Filling ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Purpose: To report the successful endovascular occlusion of a persistent endoleak owing to collateral perfusion in a 1-year-old bifurcated aortic endograft. Methods and Results: An 81-year-old man underwent endovascular repair of a 5.5-cm abdominal aortic aneurysm (AAA) with a bifurcated stent-graft in 1995; collateral perfusion of the excluded aneurysm by retrograde filling of the patent inferior mesenteric artery (IMA) was noted postoperatively. At his 1-year follow-up, the mid-sac endoleak persisted on contrast-enhanced computed tomography. Using the superior mesenteric artery for access, the stump of the IMA was successfully embolized with glue. Conclusions: This case, which highlights the importance of documenting a patent IMA prior to AAA endografting, illustrates one option for the management of persistent collateral perfusion of endovascularly excluded aneurysms.

scholarly journals A case of successful surgical treatment of a ruptured giant aneurysm of the infrarenal aorta in an elderly patient

2021 ◽  
pp. 157-163
Author(s):  
A. E. Zotikov ◽  
M. R. Khokonov ◽  
K. Kh. Eminov ◽  
A. M. Solovieva ◽  
A. V. Kozhanova ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Abdominal Aortic Aneurysm ◽  
Surgical Treatment ◽  
Aortic Aneurysm ◽  
Giant Aneurysm ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Infrarenal Aorta ◽  
Giant Aneurysms ◽  
Abdominal Aortic

Today, abdominal aortic aneurysm surgery is a fairly well-studied area of medicine. Nevertheless, some questions remain rather debatable. No clear criteria for giant aneurysms have been developed so far. The available foreign and domestic literature reports about 40 cases of surgical treatment of giant abdominal aortic aneurysms, 16 of which are cases of aneurysm rupture. Open surgery remains the method of choice in the treatment of giant aneurysms due to the pronounced technical difficulties of endovascular intervention. The authors present a case of successful surgical treatment of a giant aneurysm rupture in an elderly patient. The peculiarity of this patient's condition is the occurrence of aneurysm rupture after hospital admission. The patient refused surgical treatment for two years after aneurysm detection. On examination after admission, multispiral computed tomography revealed an aneurysm size of 101 mm. On the eve of surgery, pain syndrome in the left abdomen and tachycardia appeared. Aneurysm rupture was suspected and the patient was urgently admitted to the operating room. The surgery was performed under the conditions of machine reinfusion of autoblood. The patient underwent abdominal aortic aneurysm resection with linear prosthesis and retroperitoneal hematoma removal. The postoperative period had no peculiarities. On the 10th day after the operation the patient was discharged in satisfactory condition to the outpatient treatment. This clinical case demonstrates the possibility of successful surgical treatment of giant aneurysm rupture in elderly patients.

scholarly journals ASSESSMENT OF CLINICAL PRESENTATION OF ABDOMINAL AORTIC ANEURISM

2018 ◽  
Vol 5 (4) ◽  
pp. 161-164
Author(s):  
V. Boiko ◽  
O. Buchneva ◽  
Ya. Shafer ◽  
Yu. Pisklova ◽  
A. Krylova
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Clinical Manifestations ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Vascular Involvement ◽  
Urgent Surgery ◽  
Abdominal Aortic ◽  
Abdominal Aortic Aneurism ◽  
Causes Of Mortality

Boyko V., Buchneva O. Shafer Ya., Pisklova Yu., Krylova O.To date, vascular disease rank first (more than 50%) among the causes of mortality in Ukraine. Atherosclerotic vascular involvement, being the most frequent etiological factor of abdominal aortic aneurysm, in the absence of timely diagnosis and treatment, causes severe complications, early disability and death. Clinical and functional diversity of abdominal aortic aneurysm causes difficulties in diagnosing, defining different therapeutic approaches, methods of operation and protection of visceral organs and spinal cord. The article analyzes various clinical manifestations of abdominal aortic aneurysms in 264 patients who underwent surgical treatment at the State Facility V.T Zaytsev Institute of General and Urgent Surgery from 2010 to 2018.Key words:a bdominal aortic aneurysm, rupture of abdominal aortic aneurysm РезюмеАНАЛІЗ КЛІНІЧНОГО ПЕРЕБІГУ АНЕВРИЗМ ЧЕРЕВНОГО ВІДДІЛУ АОРТИБойко В., Бучнєва О., Шафер Я., Пісклова Ю., Крилова О.На сьогоднішній деньзахворювання судин займають перше місце (більше 50%) серед причин смертності в Україні. Атеросклеротичнеураженнясудин, будучи найбільш частим етіологічним фактороманевризм черевного відділу аорти, за відсутності своєчасної діагностики і лікування викликає важкі ускладнення, ранню інвалідизацію і смерть. Клінічне і функціональне різноманіття аневризм черевної аорти викликає труднощі в діагностиці, визначає різну тактику лікування, способи операції тазахисту внутрішніх органів і спинного мозку. У статті проаналізовані різноманітні клінічні презентації аневризм черевного відділу аорти у 264 пацієнтів, яким було проведено хірургічне лікування на базі ДУ "ІЗНХ ім.В. Т.Зайцева" з 2010 по 2018 рік. Ключові слова: аневризма черевної аорти, розрив аневризми черевної аорти РезюмеАНАЛИЗ КЛИНИЧЕСКОГО ТЕЧЕНИЯ АНЕВРИЗМ БРЮШНОГО ОТДЕЛА АОРТЫБойко В., Бучнева О., Шафер Я., Писклова Ю., Крылова А.На сегодняшний день заболевания сосудов занимают первое место (более 50%) среди причин смертности в Украине. Атеросклеротическом поражении сосудов, являясь наиболее частым этиологическим фактором аневризм брюшного отдела аорты, при отсутствии своевременной диагностики и лечения вызывает тяжелые осложнения, раннюю инвалидизацию и смерть. Клиническое и функциональное многообразие аневризм брюшной аорты вызывает трудности в диагностике, определяет разную тактику лечения, способы операции и защиты внутренних органов и спинного мозга. В статье проанализированы разнообразные клинические презентации аневризм брюшного отдела аорты у 264 пациентов, которым было проведено хирургическое лечение на базе ДУ "ІЗНХ ім.В. Т.Зайцева" с 2010 по 2018 год.Ключевые слова: аневризма брюшной аорты, разрыв аневризмы брюшной аорты

scholarly journals On the Relative Impact of Intraluminal Thrombus Heterogeneity on Abdominal Aortic Aneurysm Mechanics

2019 ◽  
Vol 141 (11) ◽  
Author(s):  
Joseph R. Leach ◽  
Evan Kao ◽  
Chengcheng Zhu ◽  
David Saloner ◽  
Michael D. Hope
Keyword(s):  
Finite Element Analysis ◽  
Finite Element ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Rupture Risk ◽  
Intraluminal Thrombus ◽  
Element Analysis ◽  
Aneurysm Wall ◽  
Abdominal Aortic

Intraluminal thrombus (ILT) is present in the majority of abdominal aortic aneurysms (AAA) of a size warranting consideration for surgical or endovascular intervention. The rupture risk of AAAs is thought to be related to the balance of vessel wall strength and the mechanical stress caused by systemic blood pressure. Previous finite element analyses of AAAs have shown that ILT can reduce and homogenize aneurysm wall stress. These works have largely considered ILT to be homogeneous in mechanical character or have idealized a stiffness distribution through the thrombus thickness. In this work, we use magnetic resonance imaging (MRI) to delineate the heterogeneous composition of ILT in 7 AAAs and perform patient–specific finite element analysis under multiple conditions of ILT layer stiffness disparity. We find that explicit incorporation of ILT heterogeneity in the finite element analysis is unlikely to substantially alter major stress analysis predictions regarding aneurysm rupture risk in comparison to models assuming a homogenous thrombus, provided that the maximal ILT stiffness is the same between models. Our results also show that under a homogeneous ILT assumption, the choice of ILT stiffness from values common in the literature can result in significantly larger variations in stress predictions compared to the effects of thrombus heterogeneity.

A Comparative Study of Biomechanical and Geometrical Attributes of Abdominal Aortic Aneurysms in the Asian and Caucasian Populations

2020 ◽  
Vol 142 (6) ◽  
Author(s):  
Tejas Canchi ◽  
Sourav S. Patnaik ◽  
Hong N. Nguyen ◽  
E. Y. K. Ng ◽  
Sriram Narayanan ◽  
...  
Keyword(s):  
Wall Thickness ◽  
Gaussian Curvature ◽  
Wall Stress ◽  
Aneurysm Rupture ◽  
Aortic Aneurysms ◽  
Patient Specific ◽  
Backward Elimination ◽  
Abdominal Aortic ◽  
Highly Correlated ◽  
Peak Wall Stress

Abstract In this work, we provide a quantitative assessment of the biomechanical and geometric features that characterize abdominal aortic aneurysm (AAA) models generated from 19 Asian and 19 Caucasian diameter-matched AAA patients. 3D patient-specific finite element models were generated and used to compute peak wall stress (PWS), 99th percentile wall stress (99th WS), and spatially averaged wall stress (AWS) for each AAA. In addition, 51 global geometric indices were calculated, which quantify the wall thickness, shape, and curvature of each AAA. The indices were correlated with 99th WS (the only biomechanical metric that exhibited significant association with geometric indices) using Spearman's correlation and subsequently with multivariate linear regression using backward elimination. For the Asian AAA group, 99th WS was highly correlated (R2 = 0.77) with three geometric indices, namely tortuosity, intraluminal thrombus volume, and area-averaged Gaussian curvature. Similarly, 99th WS in the Caucasian AAA group was highly correlated (R2 = 0.87) with six geometric indices, namely maximum AAA diameter, distal neck diameter, diameter–height ratio, minimum wall thickness variance, mode of the wall thickness variance, and area-averaged Gaussian curvature. Significant differences were found between the two groups for ten geometric indices; however, no differences were found for any of their respective biomechanical attributes. Assuming maximum AAA diameter as the most predictive metric for wall stress was found to be imprecise: 24% and 28% accuracy for the Asian and Caucasian groups, respectively. This investigation reveals that geometric indices other than maximum AAA diameter can serve as predictors of wall stress, and potentially for assessment of aneurysm rupture risk, in the Asian and Caucasian AAA populations.

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