Sleep-wake states ub transgenic mouse models overexpressing the human β-amyloid precursor protein

2005 ◽  
Vol 20 (2) ◽  
pp. 87-90 ◽  
Author(s):  
Salvador Huitrón-Reséndiz ◽  
Manuel Sánchez-Alavez ◽  
José R. Criado
Keyword(s):  
Amyloid Precursor Protein ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Precursor Protein ◽  
Transgenic Mouse Models ◽  
Β Amyloid

Dynamics of Aβ Turnover and Deposition in Different β-Amyloid Precursor Protein Transgenic Mouse Models Following γ-Secretase Inhibition

2008 ◽  
Vol 327 (2) ◽  
pp. 411-424 ◽  
Author(s):  
Dorothee Abramowski ◽  
Karl-Heinz Wiederhold ◽  
Ulrich Furrer ◽  
Anne-Lise Jaton ◽  
Anton Neuenschwander ◽  
...  
Keyword(s):  
Amyloid Precursor Protein ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Precursor Protein ◽  
Transgenic Mouse Models ◽  
Β Amyloid

Transgenic mouse models of Alzheimer's disease: phenotype and mechanisms of pathogenesis

2001 ◽  
Vol 67 ◽  
pp. 195-202 ◽  
Author(s):  
Karen Duff
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Precursor Protein ◽  
Transgenic Mouse Models ◽  
Disease Phenotype

A range of transgenic mice have been created to model Alzheimer's disease. These include mice expressing human forms of the amyloid precursor protein, the presenilins and, more recently, tau. Several of the models develop features of the disease including amyloid pathology, cholinergic deficits, neurodegeneration and cognitive impairment. Progress in the characterization and use of these model animals is discussed.

scholarly journals Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1997 ◽  
Vol 94 (24) ◽  
pp. 13287-13292 ◽  
Author(s):  
C. Sturchler-Pierrat ◽  
D. Abramowski ◽  
M. Duke ◽  
K.-H. Wiederhold ◽  
C. Mistl ◽  
...  
Keyword(s):  
Alzheimer Disease ◽  
Amyloid Precursor Protein ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Precursor Protein ◽  
Transgenic Mouse Models

scholarly journals Effect of Alzheimer’s disease‐related β‐amyloid peptide conformations in transgenic mouse models of β‐amyloidosis

2020 ◽  
Vol 16 (S2) ◽  
Author(s):  
Marina Célestine ◽  
Muriel Jacquier‐Sarlin ◽  
Eve Borel ◽  
Anne‐Sophie Herard ◽  
Alain Buisson ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Transgenic Mouse ◽  
Mouse Models ◽  
Amyloid Peptide ◽  
Transgenic Mouse Models ◽  
Peptide Conformations ◽  
Β Amyloid ◽  
Β Amyloid Peptide
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