Quantitative Trait Loci Influencing Hepatic Copper in Rats

2002 ◽  
Vol 227 (7) ◽  
pp. 529-534 ◽  
Author(s):  
I.D. de Wolf ◽  
A.C.M. Bonné ◽  
X.M. Fielmich-Bouman ◽  
B.A. van Oost ◽  
A.C. Beynen ◽  
...  
Keyword(s):  
Quantitative Trait ◽  
Copper Content ◽  
Major Quantitative Trait Locus ◽  
Genetic Variance ◽  
Inbred Strains ◽  
Chromosome 2 ◽  
Hepatic Copper ◽  
Liver Copper ◽  
Animal Liver ◽  
Trait Locus

Significant differences in liver copper content have been observed between rat inbred strains. To define loci controlling this trait, the offspring (n = 190) from an (LEW/OlaHsd × BC/CpbU) F2-intercross was genetically analyzed. From each F2 animal, liver copper content was determined and genomic DNA was screened with polymorphic DNA markers. We found a major quantitative trait locus (QTL) for liver copper content in females on chromosome 2 and in males on chromosome 10. Both QTLs accounted for approximately 20% of the genetic variance. In addition, suggestive linkage for liver copper content was found on rat chromosomes 1, 8, 10, 12, 14, and 19. The regions on these chromosomes contain genes that are responsible for 9.0–15.5% of the genetic variance of liver copper content.

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1997 ◽  
Vol 15 (3) ◽  
pp. 273-276 ◽  
Author(s):  
Anthony G. Comuzzie ◽  
James E. Hixson ◽  
Laura Almasy ◽  
Braxton D. Mitchell ◽  
Michael C. Mahaney ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Human Chromosome ◽  
Fat Mass ◽  
Quantitative Trait ◽  
Major Quantitative Trait Locus ◽  
Chromosome 2 ◽  
Serum Leptin ◽  
Trait Locus

scholarly journals Identification of A Major Quantitative Trait Locus for Grain Weight In Rice Using Microsatellite Marker

2017 ◽  
Vol 21 (4) ◽  
Author(s):  
Mariana Susilowati ◽  
Hajrial Aswidinnoor ◽  
Wening Enggarini ◽  
Kurniawan Rudi Trijatmiko
Keyword(s):  
Quantitative Trait Locus ◽  
Microsatellite Marker ◽  
Quantitative Trait ◽  
Major Quantitative Trait Locus ◽  
Grain Weight ◽  
Trait Locus

Mapping and validation of a major quantitative trait locus qRN5a associated with increasing root number under low potassium in rice

2020 ◽  
Vol 90 (3) ◽  
pp. 519-528 ◽  
Author(s):  
Anowerul Islam ◽  
Yingxin Zhang ◽  
Galal Anis ◽  
M. H. Rani ◽  
Workie Anley ◽  
...  
Keyword(s):  
Quantitative Trait Locus ◽  
Quantitative Trait ◽  
Major Quantitative Trait Locus ◽  
Root Number ◽  
Low Potassium ◽  
Trait Locus
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