Better analysis using the models and simulations hierarchy

2018 ◽  
Vol 15 (3) ◽  
pp. 279-288
Author(s):  
Mark A Gallagher ◽  
Daniel V Hackman ◽  
Alisha A Lad
Keyword(s):  
Hierarchy Level ◽  
Present Information ◽  
Resolution Model ◽  
Hierarchy Of Models

We review the hierarchy of models and simulations (M&S) that categorize analysis of conflict. We build on this M&S hierarchy to provide a framework to assess the tools, data, people, processes, and partnerships. The framework provides a means to assess the analytic ability of an organization, describes the resolution and scopes of the parts of the system (tools or people, for examples), or can characterize the scope, applicability, and rigor of a particular study. We examine the process of incorporating the results from a model at one level of the hierarchy into a model at another hierarchy level, either more-aggregate or higher-resolution. Firstly, we describe the process of incorporating results from more-aggregate models as inputs in a higher-resolution model, which is often done to set the context. Then, we present information on the process of using the results of higher-resolution models as inputs in more-aggregate models.

The Potentials of Scanning Microscopy

1968 ◽  
Vol 26 ◽  
pp. 352-353
Author(s):  
A. V. Crewe
Keyword(s):  
Salient Feature ◽  
Secondary Emission ◽  
Resolving Power ◽  
X Rays ◽  
Scanning Microscope ◽  
Forming Process ◽  
Additional Tool ◽  
Detection Systems ◽  
Conventional Microscope ◽  
Present Information

If the resolving power of a scanning electron microscope can be improved until it is comparable to that of a conventional microscope, it would serve as a valuable additional tool in many investigations.The salient feature of scanning microscopes is that the image-forming process takes place before the electrons strike the specimen. This means that several different detection systems can be employed in order to present information about the specimen. In our own particular work we have concentrated on the use of energy loss information in the beam which is transmitted through the specimen, but there are also numerous other possibilities (such as secondary emission, generation of X-rays, and cathode luminescence).Another difference between the pictures one would obtain from the scanning microscope and those obtained from a conventional microscope is that the diffraction phenomena are totally different. The only diffraction phenomena which would be seen in the scanning microscope are those which exist in the beam itself, and not those produced by the specimen.

Three-Dimensional reconstruction of isolated centrosomes by automated electron tomography

1994 ◽  
Vol 52 ◽  
pp. 310-311
Author(s):  
M.B. Braunfeld ◽  
M. Moritz ◽  
B.M. Alberts ◽  
J.W. Sedat ◽  
D.A. Agard
Keyword(s):  
Electron Tomography ◽  
Three Dimensional ◽  
Vital Role ◽  
Complex Nature ◽  
Animal Cells ◽  
Microtubule Organizing Center ◽  
Nucleation Sites ◽  
Dimensional Reconstruction ◽  
Organizing Center ◽  
Resolution Model

In animal cells, the centrosome functions as the primary microtubule organizing center (MTOC). As such the centrosome plays a vital role in determining a cell's shape, migration, and perhaps most importantly, its division. Despite the obvious importance of this organelle little is known about centrosomal regulation, duplication, or how it nucleates microtubules. Furthermore, no high resolution model for centrosomal structure exists.We have used automated electron tomography, and reconstruction techniques in an attempt to better understand the complex nature of the centrosome. Additionally we hope to identify nucleation sites for microtubule growth.Centrosomes were isolated from early Drosophila embryos. Briefly, after large organelles and debris from homogenized embryos were pelleted, the resulting supernatant was separated on a sucrose velocity gradient. Fractions were collected and assayed for centrosome-mediated microtubule -nucleating activity by incubating with fluorescently-labeled tubulin subunits. The resulting microtubule asters were then spun onto coverslips and viewed by fluorescence microscopy.

Reforming Arab Reason

2018 ◽  
Vol 11 (1-2) ◽  
pp. 19-42
Author(s):  
Khalid Shibib
Keyword(s):  
Arab World ◽  
Legal Reasoning ◽  
Decisive Role ◽  
Arab Countries ◽  
Religious Knowledge ◽  
Intrinsic Factors ◽  
Knowledge Based ◽  
Present Information ◽  
Cultural Construct ◽  
Political Economic

As a humanitarian worker who was professionally involved for decades in crisis- and war-shaken countries, the author strove to understand the political, socioeconomic, and cultural factors contributing to conflicts. This contextualization, with a focus on Arab countries, confirmed what other thinkers found: the majority of political, economic, social, cultural, religious, and finally humanitarian crises in the Arab world are man-made and can be attributed to both extrinsic and intrinsic factors. Central to the latter appears to be a shared cultural construct that can be termed “Arab reason.” This essay tries to present information on various aspects of the crisis; to understand why reform efforts come so late and why are they are more difficult for Arabs than for other Muslims. It continues by looking at the knowledge systems that govern Arab reason and their evolution, including the decisive role of the religious knowledge system. From there, it proposes some reform ideas including a renewed legal reasoning process with the goal of a future-oriented, knowledge-based, and inclusive Arab Islamic vision. A pragmatic way forward could be an additional unifying eighth legal school (madhhab/madhāhib) to counter sectarian conflicts and violence. This essay is built on a targeted literature search and is not a comprehensive review of the growing literature generated by distinguished thinkers on various aspects of Arab Islamic identity.

Dealing with imperfect elicitation results

2019 ◽  
Author(s):  
Rens van de Schoot ◽  
Elian Griffioen ◽  
Sonja Désirée Winter
Keyword(s):  
Statistical Parameter ◽  
Research Practices ◽  
Popular Method ◽  
Questionable Research Practices ◽  
Present Information

The trial-and-roulette method is a popular method to extract experts’ beliefs about a statistical parameter. However, most studies examining the validity of this method only use ‘perfect’ elicitation results. In practice, it is sometimes hard to obtain such neat elicitation results. In our project about predicting fraud and questionable research practices among PhD candidates, we ran into issues with imperfect elicitation results. The goal of the current chapter is to provide an over-view of the solutions we used for dealing with these imperfect results, so that others can benefit from our experience. We present information about the nature of our project, the reasons for the imperfect results, and how we resolved these sup-ported by annotated R-syntax.

A Review on Ethnobotanical, Phytochemical, Pharmacological and Traditional Aspects of Indigenous Indian Herb Trachyspermum ammi (L)

2020 ◽  
Vol 6 (3) ◽  
pp. 172-187 ◽  
Author(s):  
Nikita Saraswat ◽  
Neetu Sachan ◽  
Phool Chandra
Keyword(s):  
Chemical Constituents ◽  
Collective Data ◽  
Trachyspermum Ammi ◽  
Present Information ◽  
Gastrointestinal Problems ◽  
Vedic Literature ◽  
Key Terms ◽  
Phytochemical Studies ◽  
Near Future

Introduction and Ethnopharmacological relevance: In the Indian Vedic literature, Charakasamhita and Sushritasamhita, the Ajwain is known as Bhootika and in the charaksamhita commentaries, it is termed as Yavanika. The medicinal role of Ajwain fruit is claimed to be very important in the treatment of many ailments in humans. The plant Trachyspermum ammi Linn. is a grassy, aromatic annual plant, which falls in the family Umbelliferae. This plant is grown in India, Iran, Pakistan, Egypt, etc. for its medicinal benefits. Tribals of India use it for the treatment of diarrhea, arthritis, colic and gastrointestinal problems. In the traditional preparations, Indian Vaidya guru’s (Ayurveda Guru’s), the ajwain extract is used as “Admoda Arka”. The Ayurveda doctors, hakims and Vaidya gurus recommend ajwain for treating headaches, cold, flu and even during painful menstrual periods. Aim of the Study: The review paper has compiled the researches conducted on Trachyspermum ammi, which will help in presenting a collective data of the authentic researches conducted on the plant worldwide. It will also present information about the phytoconstituents which can be useful for building up new researches in near future. Materials and Methods: This paper has been prepared by collecting all the information available on the following platforms and the papers were searched from 1975 to 2019. The databases and electronic journals were well searched including Wiley, Springer link, Google Scholar, Science Direct, Pubmed. The key terms used for the search were Ajwain, C. copticum, Trachyspermum ammi and other synonyms of the plant. The search was also done by the names of chemical constituents present in the plant and the pharmacological effect of the plant. Results: The multiple uses of T. ammi are due to the active constituents present in it. As per the phytochemical studies on the fruits of T. ammi, the presence of various phytoconstituents has been found such as saponins, flavonoids, alkaloids, glycosides, fixed oils, thymenes, cumenes, tannins, amino acids, p-cymene, c-terpinene, steroids, etc. Conclusions: This paper is focused on presenting a detailed review on the literature, pharmacological properties, physicochemical studies and the newest researches on the plant. In this paper, we have also compiled the traditional uses of the herb used by Indian peopleon recommendations from their Hakims, Vaidya and use of the herbs by many tribes all across India and Pakistan.

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