scholarly journals Pulchranins B and C, New Acyclic Guanidine Alkaloids from the Far-Eastern Marine Sponge Monanchora Pulchra

2013 ◽  
Vol 8 (9) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Tatyana N. Makarieva ◽  
Ekaterina K. Ogurtsova ◽  
Yuliya V. Korolkova ◽  
Yaroslav A. Andreev ◽  
Irina V. Mosharova ◽  
...  
Keyword(s):  
Natural Products ◽  
Marine Sponge ◽  
Marine Natural Products ◽  
Ms Analysis ◽  
Guanidine Alkaloids ◽  
Far Eastern

New marine natural products, pulchranins B and C (2 and 3), were isolated from the marine sponge Monanchora pulchra and their structures were established using NMR and MS analysis. Compounds 2 and 3 were moderately active as inhibitors of TRPV1 (EC50 value of 95 and 183 μM, respectively) and less potent against TRPV3 and TRPA1 receptors.

scholarly journals Marine Natural Products. XXXVII. Aragusteroketals A and C, Two Novel Cytotoxic Steroids from a Marine Sponge of Xestospongia sp.

1996 ◽  
Vol 44 (10) ◽  
pp. 1840-1842 ◽  
Author(s):  
Motomasa KOBAYASHI ◽  
Yin-Ju CHEN ◽  
Kouichi HIGUCHI ◽  
Shunji AOKI ◽  
Isao KITAGAWA
Keyword(s):  
Natural Products ◽  
Marine Sponge ◽  
Marine Natural Products ◽  
Cytotoxic Steroids

scholarly journals Marine natural products. XI. An antiinflammatory scalarane-type bishomosesterterpene, foliaspongin, from the Okinawan marine sponge Phyllospongia foliascens (Pallas).

1983 ◽  
Vol 31 (2) ◽  
pp. 552-556 ◽  
Author(s):  
HIROYUKI KIKUCHI ◽  
YASUMASA TSUKITANI ◽  
IWAO SHIMIZU ◽  
MOTOMASA KOBAYASHI ◽  
ISAO KITAGAWA
Keyword(s):  
Natural Products ◽  
Marine Sponge ◽  
Marine Natural Products

scholarly journals Normonanchocidins G and H, New Pentacyclic Guanidine Alkaloids from the Far-Eastern Marine Sponge Monanchora pulchra

2017 ◽  
Vol 12 (7) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Kseniya M. Tabakmakher ◽  
Tatyana N. Makarieva ◽  
Vladimir A. Denisenko ◽  
Roman S. Popov ◽  
Aleksandra S. Kuzmich ◽  
...  
Keyword(s):  
Marine Sponge ◽  
Hela Cells ◽  
Data Interpretation ◽  
2D Nmr ◽  
Cytotoxic Activities ◽  
Human Leukemia ◽  
Acid Moiety ◽  
Spectrometric Data ◽  
Guanidine Alkaloids ◽  
Far Eastern

Two new pentacyclic guanidine alkaloids, normonanchocidins G (1) and H (2) containing an unusual ω-2-hydroxy fatty acid moiety were isolated from the Far-Eastern marine sponge Monanchora pulchra. The structures of 1 and 2 were determined by 1D- and 2D-NMR spectroscopic and mass spectrometric data interpretation. Compounds 1 and 2 exhibit potent cytotoxic activities against human leukemia THP-1, HL-60 cells, human cervical epithelioid carcinoma HeLa cells and also have high impact on ability of HeLa cells to migrate.

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