Hemifacial Spasms and Involuntary Facial Movements. Role of Magnetic Resonance in the Diagnostic Work-up

ObjectivesTo investigate how many general practitioner (GP)-referred venous thromboembolic events (VTEs) are diagnosed during 1 year in one geographical region and to investigate the (urgent) referral pathway of VTE diagnoses, including the role of laboratory D-dimer testing.DesignHistorical cohort study.SettingGP patients of 47 general practices in a demarcated geographical region of 161 503 inhabitants in the Netherlands.ParticipantsWe analysed all 895 primary care patients in whom either the GP determined a D-dimer value or who had a diagnostic work-up for suspected VTE in a non-academic hospital during 2015.Primary and secondary outcome measuresThe primary outcomes of this study were the total number of VTEs per year and the diagnostic pathways—including the role of GP determined D-dimer testing—of patients urgently referred to secondary care for suspected VTE. Additionally, we explored the use of an age-adjusted D-dimer cut-off.ResultsThe annual VTE incidence was 0.9 per 1000 inhabitants. GPs annually ordered 5.1 D-dimer tests per 1000 inhabitants. Of 470 urgently GP-referred patients, 31.3% had a VTE. Of those urgently referred based on clinical assessment only (without D-dimer testing), 73.8% (96/130) had a VTE; based on clinical assessment and laboratory D-dimer testing yielded 15.0% (51/340) VTE. Applying age-adjusted D-dimer cut-offs to all patients aged 50 years or older resulted in a reduction of positive D-dimer results from 97.9% to 79.4%, without missing any VTE.ConclusionsAlthough D-dimer testing contributes to the diagnostic work-up of VTE, GPs have a high detection rate for VTE in patients who they urgently refer to secondary care based on clinical assessment only.

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Role and Limitations of Magnetic Resonance Imaging in the Diagnostic Work-Up of Patients with Liver Cancer

Journal of Computer Assisted Tomography ◽

10.1097/00004728-199911001-00006 ◽

1999 ◽

Vol 23 ◽

pp. S39-S44 ◽

Cited By ~ 2

Author(s):

Raju Sharma ◽

Sanjay Saini

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Liver Cancer ◽

Resonance Imaging ◽

Diagnostic Work ◽

Work Up ◽

Diagnostic Work Up

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The Usefulness of Magnetic Resonance Imaging of the Cardiovascular System in the Diagnostic Work-Up of Patients With Turner Syndrome

Frontiers in Endocrinology ◽

10.3389/fendo.2018.00609 ◽

2018 ◽

Vol 9 ◽

Cited By ~ 2

Author(s):

Monika Obara-Moszynska ◽

Justyna Rajewska-Tabor ◽

Szymon Rozmiarek ◽

Katarzyna Karmelita-Katulska ◽

Anna Kociemba ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Cardiovascular System ◽

Turner Syndrome ◽

Resonance Imaging ◽

Diagnostic Work ◽

Work Up ◽

Diagnostic Work Up

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Role of colonoscopy in the diagnostic work-up of bowel endometriosis

World Journal of Gastroenterology ◽

10.3748/wjg.v21.i16.4997 ◽

2015 ◽

Vol 21 (16) ◽

pp. 4997 ◽

Cited By ~ 10

Author(s):

Marco Milone

Keyword(s):

Bowel Endometriosis ◽

Diagnostic Work ◽

Work Up ◽

Diagnostic Work Up

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Acute liver failure

Challenging Concepts in Paediatric Critical Care ◽

10.1093/med/9780198794592.003.0008 ◽

2020 ◽

pp. 89-104

Author(s):

Andrew Jones ◽

Akash Deep

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Organ Support ◽

Fulminant Liver Failure ◽

Management Of Complications ◽

Diagnostic Work ◽

Work Up ◽

Paediatric Critical Care ◽

Diagnostic Work Up

The work-up and management of patients with acute liver failure in paediatric critical care are often challenging. This chapter takes the readers through definitions, grading of severity, and diagnostic work-up of acute liver failure in children. General principles underlying the management of acute liver failure, including immediate resuscitation and retrieval; organ support, including renal replacement therapy; and the management of complications, including bleeding, are discussed. In particular, this chapter focuses on neuromonitoring and neuroprotection strategies in children with hepatic encephalopathy as a complication. The role of liver transplantation in fulminant liver failure and a brief overview of complications are also discussed.

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