scholarly journals A case report of primary cutaneous marginal zone B-cell lymphoma with mastocytosis

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110425
Author(s):  
Hyun Yi Lee ◽  
Joong Sun Lee ◽  
Dae Won Koo

A 53-year-old man presented with asymptomatic, dusky reddish nodules on his trunk, which had persisted for 7 years. Histological findings showed nodular to diffuse dermal infiltration of lymphocytes with irregular nuclei, eosinophils, plasma cells, and mast cells. CD20 revealed patch positivity. Periphery of lymphoid follicles showed BCL-2 positivity and BCL-6 positivity focally at the center. CD30 and toluidine blue staining showed positivity, and several mast cells were confirmed. The immunoglobulin heavy chain gene rearrangement result showed B-cell monoclonality. The patient’s condition was diagnosed as cutaneous marginal zone B-cell lymphoma, plasmacytoid type with mastocytosis. Primary cutaneous marginal zone B-cell lymphoma is an indolent lymphoma with a tendency for local recurrence. In the specimen obtained from our patient, multiple mast cells were observed. Primary cutaneous marginal zone B-cell lymphoma with prominent mastocytosis is rare and there are a few reported cases. Therefore, this case is worth reporting for its rarity and for the purpose of reminding mastocytosis in primary cutaneous marginal zone B-cell lymphoma.

2010 ◽  
Vol 63 (12) ◽  
pp. 1059-1065 ◽  
Author(s):  
T. Kubota ◽  
S. Moritani ◽  
T. Yoshino ◽  
H. Nagai ◽  
H. Terasaki

Cell ◽  
1986 ◽  
Vol 44 (1) ◽  
pp. 97-106 ◽  
Author(s):  
Michael L. Cleary ◽  
Timothy C. Meeker ◽  
Shoshana Levy ◽  
Elizabeth Lee ◽  
Martha Trela ◽  
...  

2021 ◽  
Author(s):  
Blake W. Boudreaux ◽  
Meera H. Patel ◽  
Caitlin M. Brumfiel ◽  
Jake Besch-Stokes ◽  
David J. DiCaudo ◽  
...  

Author(s):  
G. La Rocca ◽  
A. M. Auricchio ◽  
E. Mazzucchi ◽  
T. Ius ◽  
G. M. Della Pepa ◽  
...  

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