scholarly journals Utility of photodynamic therapy for the management of oral potentially malignant disorders and oral cancer

2016 ◽  
Vol 1 ◽  
pp. 2057178X1666916 ◽  
Author(s):  
Dimitrios Andreadis ◽  
Achilleia-Maria Pavlou ◽  
Eleni Sotiriou ◽  
Fani Vrani ◽  
Dimitrios Ioannides ◽  
...  
Author(s):  
Paresh Kumar Behera ◽  
Diksha Mohapatra

World Health Organization (WHO) defined the terminology ‘Oral Potentially malignant disorders’ (OPMD) as the presence of risk of malignancy in a lesion or condition either during the time of initial diagnosis or at a future date with the commonly accepted prevalence of 1–5%. All OPMDs may not transform into malignancy, many factors have been explored which effectively assess the risk of malignant transformation in OPMDs including many clinical, pathological and molecular factors. Qualitative & experimental factors of different cells in cytological preparations and/or biopsy specimens are reliable parameters for pathologists. The analysis and assessment of histological units can be enhanced by image analysis assisted by a computer that can be used for statistical comparisons. Fractal geometry is considered to be an ideal method of image analysis in quantitative microscopy & histopathology. Fractal dimension analysis is not only limited to determining cell and tumour types but can also be used for determining cellular behaviours in vitro such as cell migration, apoptosis and cellular differentiation, which can be a useful characterization of oral cancer lines and further help in the treatment planning. Keywords: Oral Cancer, Oral Potentially Malignant Disorders (OPMDs), Conventional morphometry, Fractal Dimension, Photomicrograph


2016 ◽  
Vol 5 (1) ◽  
pp. 52-57
Author(s):  
Neal J Mccormick ◽  
Peter J Thomson ◽  
Marco Carrozzo

Early detection of oral cancer improves survival rates significantly, however, the incidence of oral cancer has continued to rise in the UK – between 2002–2012, it increased by more than 30%.1 There is currently no national screening programme for oral cancer, so undertaking a full examination of the oral mucosa during routine dental appointments is vital. Although strong evidence is still lacking, oral cancer is thought to be preceded by oral potential malignant disorders (OPMDs) or oral precancerous diseases. These mainly present as white/red lesions within the mouth and their clinical appearance can be challenging to diagnose accurately, which can lead to them being misdiagnosed as negligible problems. Dentists must keep up to date with OPMDs detection and ensure they are capable of correctly recognising lesions that carry a potential risk. This paper aims to provide a brief overview on OPMDs, highlighting potentially malignant disorders as they may present to the practitioner, showing their typical clinical appearance, and suggesting differential diagnosis and clinical management in dental practice.


2019 ◽  
Vol 28 ◽  
pp. 146-152 ◽  
Author(s):  
Xin Jin ◽  
Hao Xu ◽  
Jing Deng ◽  
Hongxia Dan ◽  
Ping Ji ◽  
...  

Author(s):  
DANIELA BRITO BASTOS ◽  
VITOR BONETTI VALENTE ◽  
BRUNA AMÉLIA MOREIRA SARAFIM DA SILVA ◽  
SUZY ELAINE NOBRE DE FREITAS ◽  
ANA RITA ALBUQUERQUE ZITO ◽  
...  

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