Single-session versus two-session placement of chest port and gastrostomy tube in patients with head and neck cancer: Is there any difference in the device-related early infection rates?

Background It is unknown whether placement of a chest port (port) and a gastrostomy tube (G-tube) in a single session increases the risk of the early device infections in patients with head and neck cancer (HNC) undergoing chemoradiation. Purpose To compare the incidence of early (≤30 days) port and G-tube infections placed in a single session compared to two separate sessions in patients with HNC. Material and Methods Between January 2012 and December 2019, 169 patients with HNC undergoing chemoradiation had a port and a G-tube placed in a single session (single-session group), while 25 had both devices placed in two separate sessions (two-session group) within 30 days of each other. The incidence of early device infections was compared between groups. Logistic regression analysis was conducted to determine if the number of sessions was a variable affecting device infections. Results A total of 6 (3%) early port infections and 13 (6.7%) early G-tube infections were identified. The two groups did not significantly differ in the incidence of early port infections (3.0%, 5/169 and 4.0%, 1/25, p = 0.59) nor early G-tube infections (7.1%, 12/169 and 4.0%, 1/25, p = 1.0). The number of sessions for device placement was not a variable affecting overall device infections in logistic regression analyses (odds ratio: 1.24, 95% confidence interval: 0.20–7.82, p = 0.82) after controlling for potential confounding variables. Conclusions The risk of early device infections in single-session placement appeared to be the same as two-session placement in patients with HNC undergoing chemoradiation.

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Single session placement of chest port and gastrostomy tube in patients with head and neck cancer: is there any increased risk for device infection?

Journal of Vascular and Interventional Radiology ◽

10.1016/j.jvir.2015.12.720 ◽

2016 ◽

Vol 27 (3) ◽

pp. S284

Author(s):

P. Skummer ◽

K. Kobayashi ◽

J. Patel ◽

M. Faridnia ◽

M. Jawed ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Gastrostomy Tube ◽

Single Session ◽

Chest Port ◽

Increased Risk ◽

Device Infection

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Effects of in IL-1B/IL-1RN variants on the susceptibility to head and neck cancer in a chinese Han population

Cancer Cell International ◽

10.1186/s12935-021-01750-0 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yanhai Yin ◽

Fen Li ◽

Liangqian Tong ◽

Chunru Chen ◽

Bo Yuan

Keyword(s):

Logistic Regression ◽

Head And Neck Cancer ◽

Head And Neck ◽

Genetic Association ◽

Neck Cancer ◽

Chinese Han Population ◽

Nucleotide Polymorphisms ◽

Chinese Han ◽

Han Population ◽

Logistic Regression Models

Abstract Background The study aimed to evaluate the relationship of IL-1B/IL-1RN polymorphisms to the predisposition of head and neck cancer (HNC) in a Chinese Han population. Methods Nine single-nucleotide polymorphisms (SNPs) in IL-1B/IL-1RN were genotyped based on Agena MassARRAY platform. Logistic regression models were used to analyze the genetic association between these SNPs and HNC risk by calculating odds ratios (ORs) and 95% confidence intervals (CI). Haplotype analysis were performed using Haploview program and logistic regression model. Results The genetic association between rs1143643 in IL-1B and the higher risk of HNC was found (OR = 1.23, 95% CI 1.04–1.46) in the overall. IL-1RN rs17042888 was related to a reduced risk of HNC in the subjects aged > 46 years (OR = 0.70, 95% CI: 0.50–0.98) and in females (OR = 0.71, 95% CI 0.52–0.98), while rs1143643 increased the predisposition of HNC among females (OR = 1.76, 95% CI 1.13–2.74). Furthermore, rs1143643 had an increased susceptibility to thyroid carcinoma (OR = 1.61, 95% CI 1.10–2.34). Moreover, compared with stage I–II, the frequency of IL-1RN rs452204-AG genotype was lower in patients with stage III–IV. Conclusions IL-1B (rs1143643) and IL-1RN (rs17042888 and rs452204) polymorphisms might be related to the individual susceptibility of HNC in the Chinese Han population. These results might help to improve the understanding of IL-1B and IL-1RN genes in the occurrence of HNC.

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