Ultrasound of Focal Salivary Gland Lesions

Ultrasound ◽  
2009 ◽  
Vol 17 (3) ◽  
pp. 124-130
Author(s):  
Rajat Chowdhury ◽  
Hazel A Pratt ◽  
Keith C Dewbury ◽  
Elizabeth E Rutherford
Keyword(s):  
Salivary Gland ◽  
Imaging Modality ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
Imaging Features ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Diagnostic Uncertainty ◽  
Sensitive Tool ◽  
Initial Imaging

Ultrasound is a sensitive tool for assessing focal salivary gland lesions and is the initial imaging modality of choice for investigating such conditions. Whilst certain lesions have very characteristic ultrasound appearances, many hyperechoic lesions have non-specific imaging features resulting in diagnostic uncertainty based on imaging alone. Here we review the appearances of these lesions on ultrasound and highlight the importance of proceeding to ultrasound-guided fine-needle aspiration for cytology or core biopsy to reach a definitive diagnosis.

Utility and Safety of Ultrasound-Guided Fine-Needle Aspiration of Salivary Gland Masses Including a Cytologist's Review

2004 ◽  
Vol 23 (6) ◽  
pp. 777-783 ◽  
Author(s):  
Bettina Siewert ◽  
Jonathan B. Kruskal ◽  
Denis Kelly ◽  
Jacob Sosna ◽  
Robert A. Kane
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle

Ultrasound-Guided Fine Needle Aspiration of Major Salivary Gland Masses and Adjacent Lymph Nodes

2011 ◽  
Vol 27 (2) ◽  
pp. 105-113 ◽  
Author(s):  
Alexander S. Jung ◽  
Gaurav Sharma ◽  
Dennis Maceri ◽  
Dale Rice ◽  
Sue Ellen Martin ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Lymph Nodes ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Major Salivary Gland ◽  
Ultrasound Guided ◽  
Fine Needle

scholarly journals Adult exogenous lipoid pneumonia: A rare and underrecognized entity in cytology – A case series

CytoJournal ◽  
2018 ◽  
Vol 15 ◽  
pp. 17 ◽  
Author(s):  
Simon Sung ◽  
Henry D. Tazelaar ◽  
John P. Crapanzano ◽  
Aziza Nassar ◽  
Anjali Saqi
Keyword(s):  
Case Reports ◽  
Case Series ◽  
Invasive Procedure ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
Imaging Features ◽  
Lipoid Pneumonia ◽  
Fine Needle ◽  
Cytological Features ◽  
Appropriate Therapy

Background:Exogenous lipoid pneumonia (ELP) is a rare benign entity without specific clinical or imaging presentation. Although cytological studies – either bronchoalveolar lavage (BAL) or fine-needle aspiration (FNA) – may be pursued in patients with ELP, a definitive diagnosis is frequently rendered only on histology. The aim of this study is to highlight the cytological features of ELP.Methods:A search of cytopathology (CP) and surgical pathology (SP) diagnoses of ELP was conducted. The corresponding clinical and imaging features were obtained, and the morphology, particularly the presence and size of the intracytoplasmic vacuoles and background, was assessed.Results:Nine cases of ELP were identified, including eight with corresponding CP and SP. A neoplasm was suspected in three based on imaging, but ELP was not in the differential clinically or radiographically in any. Among the cases, six patients had BALs and three FNAs. All of the samples showed multiple large vacuoles within macrophages with at least some equal to or larger than the size of the cell nucleus. Similar vacuoles were noted extracellularly on smears.Conclusions:ELP is typically described in case reports in the clinical or radiological literature. To the best of our knowledge, this represents the largest series of adult ELP in CP. When large vacuoles are present in macrophages in cytology specimens, at least a suspicion of ELP can be suggested to initiate appropriate therapy, identify/remove the inciting agent, and preclude a more invasive procedure.

Applications of Computational Pathology in Head and Neck Cytopathology

2021 ◽  
pp. 1-5
Author(s):  
Trang K. Lollie ◽  
Jeffrey F. Krane
Keyword(s):  
Squamous Cell Carcinoma ◽  
Salivary Gland ◽  
Head And Neck ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Diagnostic Uncertainty ◽  
Potential Applications ◽  
Computational Methodology ◽  
Computational Pathology ◽  
Computational Technology

Background: The application of computational technology to head and neck cytology material has been explored experimentally in several areas with a variety of potential applications. Summary: This review summarizes the application of these techniques to the diagnosis of thyroid, salivary gland, and other head and neck fine-needle aspiration specimens. Current limitations and potential future applications in diagnosis are discussed along with the possibilities for therapeutic applications of computational methodology. Key Message: Particularly promising applications include resolving diagnostic uncertainty in indeterminate thyroid aspirates and assessing the tumor microenvironment in response to immunotherapy for squamous cell carcinoma.

scholarly journals Role of endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of space occupying lesions of the pancreas

2014 ◽  
Vol 05 (03) ◽  
pp. 110-113 ◽  
Author(s):  
S. Palaniappan ◽  
M. A. Arvind ◽  
Jothimani Dinesh ◽  
Srinivas Melpakam ◽  
Srinivasan Vijaya ◽  
...  
Keyword(s):  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Final Diagnosis ◽  
Needle Aspiration ◽  
Definitive Diagnosis ◽  
Benign Lesions ◽  
Ultrasound Guided ◽  
Predictive Values ◽  
Fine Needle

Abstract Introduction: Space occupying lesions (SOLs) of the pancreas are commonly encountered in day to day practice either as an incidental finding or during evaluation of symptomatic patients. The aim of the present study was to compare the final diagnosis at follow-up with diagnosis made at computed tomography (CT)/magnetic resonance imaging (MRI) and endoscopic ultrasound (EUS). Materials and Methods: Retrospective analysis of EUS data of 131 patients referred for tissue diagnosis of SOL in pancreas was done. The lesions were classified as malignant, benign, and nonneoplastic by both CT/MRI and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in conjunction with clinical presentation, biochemical parameters, and tumor markers. Follow-up cases with a final diagnosis alone were included for the comparative analysis. Statistical Analysis: Chi-square test, sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) for CT/MRI and EUS-FNA were computed against the follow-up data. Results: Of the 131, there were 78 males (59.5%). The median age of presentation was 48 years (range: 11–82 years. Follow-up information on the final diagnosis was available for 54 patients. Confirmed diagnosis at follow-up was malignant lesion in 18, benign in 13 and 23 with a nonneoplastic lesion. When EUS-FNA outcome was compared with the definitive diagnosis of the 54 patients, it had a higher sensitivity for malignant (66.7% vs. 61.1%) and nonneoplastic lesions (78.3% vs. 73.9%) and was similar to CT/MRI for benign lesions (76.9% for both). EUS-FNA had a higher specificity (87.8% vs. 80.5%) with a good PPV for benign lesions (66.7% vs. 55.6%). CT/MRI was less accurate than EUS-FNA in predicting benign (79.6% vs. 85.2%) and nonneoplastic lesions (79.6% vs. 81.5%) compared to malignant lesions wherein it was similar at 81.5%. The high NPV with a lower PPV for both EUS/FNA and CT/MRI suggests that follow-up definitive diagnosis was superior to both –. Conclusions: Endoscopic ultrasound-guided fine-needle aspiration had a higher specificity, but low sensitivity for the both neoplastic and nonneoplastic lesion of the pancreas compared to the world literature. The overall EUS-FNA yield was low when compared to the follow-up definitive diagnosis.

Factors Influencing the Outcome of Ultrasound-Guided Fine-Needle Aspiration for Salivary Gland Lesion Diagnosis

2016 ◽  
Vol 35 (5) ◽  
pp. 877-883 ◽  
Author(s):  
Min Woo Kim ◽  
Dong Wook Kim ◽  
Hyun Seok Jung ◽  
Hye Jung Choo ◽  
Young Mi Park ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Factors Influencing
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