scholarly journals Metabolomic signatures in nuclear magnetic resonance spectra of exhaled breath condensate identify asthma

2012 ◽  
Vol 39 (2) ◽  
pp. 500-502 ◽  
Author(s):  
A. Sinha ◽  
V. Krishnan ◽  
T. Sethi ◽  
S. Roy ◽  
B. Ghosh ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Nuclear Magnetic Resonance Spectra ◽  
Breath Condensate ◽  
Magnetic Resonance Spectra ◽  
Nuclear Magnetic

Metabolomics of Exhaled Breath Condensate by Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry: A Methodological Approach

2020 ◽  
Vol 27 (14) ◽  
pp. 2381-2399 ◽  
Author(s):  
Mauro Maniscalco ◽  
Adele Cutignano ◽  
Debora Paris ◽  
Dominique J. Melck ◽  
Antonio Molino ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Respiratory Diseases ◽  
Biomarker Discovery ◽  
Exhaled Breath Condensate ◽  
Resonance Spectroscopy ◽  
Exhaled Breath ◽  
Breath Condensate ◽  
Nuclear Magnetic

: Respiratory diseases present a very high prevalence in the general population, with an increase in morbidity, mortality and health-care expenses worldwide. They are complex and heterogeneous pathologies that may present different pathological facets in different subjects, often with personal evolution. Therefore, there is a need to identify patients with similar characteristics, prognosis or treatment, defining the so-called phenotype, but also to mark specific differences within each phenotype, defining the endotypes. : Biomarkers are very useful to study respiratory phenotypes and endotypes. Metabolomics, one of the recently introduced “omics”, is becoming a leading technique for biomarker discovery. For the airways, metabolomics appears to be well suited as the respiratory tract offers a natural matrix, the Exhaled Breath Condensate (EBC), in which several biomarkers can be measured. In this review, we will discuss the main methodological issues related to the application of Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS) to EBC metabolomics for investigating respiratory diseases.

Biomonitoring of workers using nuclear magnetic resonance-based metabolomics of exhaled breath condensate: A pilot study

2018 ◽  
Vol 298 ◽  
pp. 4-12 ◽  
Author(s):  
Mauro Maniscalco ◽  
Debora Paris ◽  
Dominique Melck ◽  
Nunzio Chiariello ◽  
Fiorentino Di Napoli ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Pilot Study ◽  
Magnetic Resonance ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Breath Condensate ◽  
Nuclear Magnetic

scholarly journals Nuclear magnetic resonance-based metabolomics of exhaled breath condensate: methodological aspects

2012 ◽  
Vol 39 (2) ◽  
pp. 498-500 ◽  
Author(s):  
A. Motta ◽  
D. Paris ◽  
D. Melck ◽  
G. de Laurentiis ◽  
M. Maniscalco ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Exhaled Breath Condensate ◽  
Exhaled Breath ◽  
Methodological Aspects ◽  
Breath Condensate ◽  
Nuclear Magnetic
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